Protecting Frontline Health Care Workers from COVID-19 with Hydroxychloroquine Pre-exposure Prophylaxis: A structured summary of a study protocol for a randomised placebo-controlled multisite trial in Toronto, Canada
Letter
[키워드] 1:1
Activation
age
All participants
anticipated
baseline
blinded
block sizes
blocked
blood sample
Canada
Chloroquine
circulating
cirrhosis
clinical
clinician
composite endpoint
computer-generated
Concomitant medication
correlation
Course
COVID-19
COVID-19 negative
criteria
deficiency
determine
diabete
diagnostic
disease severity
dissemination
ECG
element
Encephalopathy
endothelial
Enrollment
extension
FIVE
fixed
Follow-up
G6PD
HCQ
HCW
Health care worker
Hepatitis
high risk
hospital
Hospitalization
Hospitalized
Host
Hydroxychloroquine
immune
include
individually randomized
insulin
intensive care units
Intervention
intervention arm
intubation
investigator
Laboratory
Liver disease
Long
marker
microbiologically
Mortality
multisite
neutralize
non-invasive ventilation
non-specific
number
objective
offered
Older
open label
Oropharyngeal
outcome
outcome measure
parallel-group
participant
patients
per day
Placebo
placebo-controlled
plasma
porphyria
positive
positive result
pregnant
Prevent
Primary outcome
Prophylaxis
Protecting
protocol
Psychological distress
psychological Impact
QTc
QTc interval
randomised
randomised placebo controlled trial
reactive
reduce
Registered
renal
reported
Research
Respiratory failure
risk of COVID-19
Sample size
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 virus
secondary
Seroconversion
serology
Standard
status
study period
Study protocol
Support
symptom duration
symptomatic
syndrome
Tablet
tablets
term
Toronto
Trial
two group
Two-arm
undergo
use of hydroxychloroquine
ventilator
viral PCR
Viral RNA
website
worker
[DOI] 10.1186/s13063-020-04577-8 PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04577-8 PMC 바로가기 [Article Type] Letter