Global Transmission, Spatial Segregation, and Recombination Determine the Long-Term Evolution and Epidemiology of Bovine CoronavirusesArticle Published on 2020-05-132022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] Analysis Bovine coronavirus breakpoint cause Characteristics collected conducted coronavirus diarrhea distress European Evidence Evolution France Genetic genetic diversity Genome genomic geographic clustering Infection Lineage Lower respiratory tract molecular clock Neonatal occurred pathway Population Recombination recombination event segregation sequence sequenced spike gene Transmission Variation virus whole genome widespread [DOI] 10.3390/v12050534 PMC 바로가기 [Article Type] Article
Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesisResearch Article Published on 2020-05-132022-10-04 Journal: Journal of medical virology [Category] MERS, SARS, 치료제, [키워드] adaptive Adaptive immune response Adaptive immunity Analysis antiviral drugs applied cause caused complications coronavirus COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 Disease progression early phase epithelial cell Host immune response Immunity implication Infection Influenza Influenza virus innate immune response Innate immunity Interaction lung mathematical Mortality opposite pandemic Pathogenesis patients potential treatment option SARS‐CoV‐2 virus SARS‐CoV‐2 severity Suppressing target cell‐limited model the timing viral clearance Viral load viral pathogenesis virus viruses [DOI] 10.1002/jmv.25866 PMC 바로가기 [Article Type] Research Article
Allo-priming as a universal anti-viral vaccine: protecting elderly from current COVID-19 and any future unknown viral outbreakReview Published on 2020-05-122022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, MERS, SARS, [키워드] activated Activation Anti-viral approach benefit can be used cascade cause Cell Cell therapy cells cellular chronic inflammation circulation Clinical use condition COVID-19 COVID-19 infection COVID-19 pandemic cross-reactive CTL DAMP disease effector cell elicit event Ex vivo healthy healthy donor heat shock protein immune immune system Immunity immunosenescence Immunotherapy inflammaging initiate injection limit lysed memory memory cell Multiple neutralizing antibody non-specific outbreak performed progression PROTECT provide replacing SARS-CoV-2 virus threat vaccination Vaccination strategy Vaccine variant viral disease viral infection viral outbreak viral titer [DOI] 10.1186/s12967-020-02363-3 PMC 바로가기 [Article Type] Review
Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmissionResearch Article Published on 2020-05-112022-10-31 Journal: eLife [Category] COVID-19, MERS, SARS, [키워드] approach Asymptomatic cause coronavirus disease COVID-19 COVID-19 infection COVID-19 patients COVID-19 symptom COVID-19 transmission criteria Critical detect determine develop dominant lineage emerging pathogens Evidence examined excluded FIVE Genome sequencing Government greater HCW healthcare healthcare worker healthy highlight hospital Hospital staff household contact household contacts Human independent infected individual infected with SARS-CoV-2 Infection infections Infectious disease lifted majority Mild symptom NHS no symptoms Nurse occupational health over Patient Personal protective equipment physiotherapists positive probe proportion rates of infection reflect reported required RT-PCR SARS-CoV-2 SARS-CoV-2 testing screened Screening Self-swab Significant Spread staff Symptom symptomatic Symptoms symptoms of COVID-19 tested Transmission utility Viral RNA Virology virus was used [DOI] 10.7554/eLife.58728 PMC 바로가기 [Article Type] Research Article
Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional surveyResearch Published on 2020-05-112022-10-31 Journal: Military Medical Research [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV All participant Arbidol Care cause change changes Community Contact coronavirus disease COVID-19 cross-sectional cross-sectional survey Diagnosis emotional Epidemic equipment Factors Fever first symptom healthcare Healthcare professional healthcare worker hospital infected cases Infection infection control Infection prevention Infection transmission Infection transmission route Isolation knowledge Laboratory lethargy management Mild moderate muscle ache Nurse Participants Perceived Physical examination Protective Psychological Psychological intervention Psychosocial status questionnaire recruited Result SARS-CoV-2 Stress Symptom Symptoms the epidemic thought Transmission Treatment university was obtained was related were infected were measured with COVID-19 Wuhan [DOI] 10.1186/s40779-020-00254-8 PMC 바로가기 [Article Type] Research
Susceptibility of the Elderly to SARS-CoV-2 Infection: ACE-2 Overexpression, Shedding, and Antibody-dependent Enhancement (ADE)Review Article Published on 2020-05-112022-10-31 Journal: Clinics [Category] COVID-19, MERS, SARS, [키워드] ACE-2 addressed ADE age Antibody-dependent enhancement assisted ventilation AT1R cause cellular mechanism children circulating Cohort Comorbidities coronavirus Coronaviruses country COVID-19 death death rate diabetes disease elderly enhancement Epidemics expression flu-like symptom Government Health heart tissue Hospitalization hypertension immunopathology individual Infection less MERS molecular occurred Older pandemic Pathogenesis physician raise receptor Research respiratory virus risk SARS-CoV-2 SARS-COV-2 infection severe COVID-19 shedding spreading capacity subject surpassed susceptibility susceptible the patient virus [DOI] 10.6061/clinics/2020/e1912 PMC 바로가기 [Article Type] Review Article
Porcine Epidemic Diarrhea Virus and the Host Innate Immune ResponseReview Published on 2020-05-112022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Antiviral cause coronavirus country CoV CoVs cytokine Defense diarrhea disrupt effective vaccine effector elicit epidemic diarrhea evade expression help highlight Host IFN antagonist IFN response IFNs immune immune evasion induce Infection Innate innate immune innate immune response Innate immunity Interaction involved mechanism pathway PEDV Porcine epidemic diarrhea virus provide response robust Type I IFN viral infections Viral RNA virus watery [DOI] 10.3390/pathogens9050367 PMC 바로가기 [Article Type] Review
Safety Recommendations and Medical Liability in Ocular Surgery during the COVID-19 Pandemic: An Unsolved DilemmaEditorial Published on 2020-05-092022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] activity blind Care cause coronavirus coronavirus disease country COVID-19 Critical dilemma eye eye surgery guidelines Health Health care worker imperative India Injections Intervention lack mandatory medical liability ocular ocular surgery Operating room ophthalmic pandemic pandemic era Patient patients performed problem problems recommendation recommendations reduction reduction in Safety SARS-CoV-2 significant increase surgeon surgery surgical visual impairment Volume while [DOI] 10.3390/jcm9051403 PMC 바로가기 [Article Type] Editorial
25-Hydroxyvitamin D Concentrations Are Lower in Patients with Positive PCR for SARS-CoV-2Brief Report Published on 2020-05-092022-10-31 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] 25-hydroxyvitamin D acute respiratory syndrome age cause Clinical outcome Cohort cohort of patient Concentration concentrations conducted Controlled trial coronavirus coronavirus disease COVID-19 death deficiency develop evaluate investigated Lower median value Mild observation Patient PCR PCR-positive plasma recommendation reduce reducing risk risk of infection SARS-CoV-2 severe symptoms significantly lower suggested Switzerland Vitamin D Vitamin D supplementation [DOI] 10.3390/nu12051359 PMC 바로가기 [Article Type] Brief Report
A pilot study of the antiviral activity of anionic and cationic polyamidoamine dendrimers against the Middle East respiratory syndrome coronavirusShort Communication Published on 2020-05-082022-11-01 Journal: Journal of medical virology [Category] Coronavirus, Fulltext, MERS, [키워드] added anionic Antiviral antiviral activity Antiviral agents antivirals cationic cause cell cultures Consequences coronavirus CoV decrease dendrimer effective group IMPROVE Infection intrinsic investigated MERS Middle East outcome pilot study research and analysis methods respiratory syndrome coronavirus sodium Vero cells viral disease virus virus classification were used [DOI] 10.1002/jmv.25928 PMC 바로가기 [Article Type] Short Communication