Evaluation on the use of Nanopore sequencing for direct characterization of coronaviruses from respiratory specimens, and a study on emerging missense mutations in partial RdRP gene of SARS-CoV-2호흡기 표본에서 코로나바이러스의 직접적 특성 규명을 위한 나노포어 염기서열 분석의 사용에 대한 평가 및 SARS-CoV-2의 부분 RdRP 유전자에서 출현하는 미스센스 돌연변이에 대한 연구Short Report Published on 2020-11-232022-09-10 Journal: Virology Journal [Category] SARS, 변종, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affecting Amplicon amplicons amplified antiviral drug antiviral drugs catastrophic collected component Consensus conserved coronavirus coronavirus disease Coronavirus disease 2019 Coronaviruses COVID-19 COVID-19 outbreak database Decision making diagnostic domains Efficacy etiologic agent Europe evaluated feasibility Flongle Frequency genetic marker Genome GISAID global healthcare high mutation rate highest highlight Hong Kong human coronaviruses identify knowledge MinION Missense mutation Missense mutations mutation rate mutations Nanopore nanopore sequencing nucleotide pandemic Partial platform positive provided public health RdRP RdRp gene RdRp sequences respiratory respiratory specimens RNA polymerase RNA viruses SARS-CoV-2 sequence sequenced Sequencing severe acute respiratory syndrome Coronavirus Single nucleotide variant SNV SNVs specimen specimens Spread Surveillance Vaccines variant virus [DOI] 10.1186/s12985-020-01454-3 PMC 바로가기 [Article Type] Short Report
Convenience and comfort: reasons reported for using drugs alone among clients of harm reduction sites in British Columbia, CanadaResearch Published on 2020-11-232022-10-31 Journal: Harm Reduction Journal [Category] COVID-19, [키워드] 95% CI adjusted odds ratio age alcohol Analysis Canada changes Community convenience coronavirus disease death rate Descriptive statistics distribution drug eliminating exacerbate Factor Gender highest impacted individual Intervention measure mitigate MOST multivariable logistic regression North not differ occurred opioid overdose overdose crisis Prevalence recruited reduction reported response Result risk Using alone Using drugs alone were used [DOI] 10.1186/s12954-020-00436-6 PMC 바로가기 [Article Type] Research
Diagnostic performance of chest computed tomography during the epidemic wave of COVID-19 varied as a function of time since the beginning of the confinement in France프랑스에서 격리가 시작된 이후로 시간의 함수에 따라 COVID-19의 유행병 동안 흉부 컴퓨터 단층 촬영의 진단 성능이 달라졌습니다.Research Article Published on 2020-11-232022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] be positive Chest computed tomography Chest CT COVID-19 COVID-19 pneumonia diagnose Diagnosis diagnostic dropped epidemic wave evaluate France French highest Inconclusive initial material NPV objective Patient Pneumonia positive positive PCR positive RT-PCR PPV respiratory respiratory symptom respiratory symptoms Result RT-PCR SARS-CoV2 sensitivity significantly specificity the epidemic [DOI] 10.1371/journal.pone.0242840 PMC 바로가기 [Article Type] Research Article
Informed Consent for Surgery at Resumption of Elective Activity After the First Wave of COVID-19General Surgery Published on 2020-11-232022-10-31 Journal: Cureus [Category] COVID-19, [키워드] activity Alexandra changed college Compliance conducted Consent coronavirus disease COVID COVID-19 Elective Elective surgery England Evidence First wave form forms Guidance healthcare highest Informed International litigation Local Most patient NHS pandemic Primary outcome Princess Result risk Society surgery surgical Trust Wave [DOI] 10.7759/cureus.11642 PMC 바로가기 [Article Type] General Surgery
Performance of the COVID19SEROSpeed IgM/IgG Rapid Test, an Immunochromatographic Assay for the Diagnosis of SARS-CoV-2 Infection: a Multicenter European StudySARS-CoV-2 감염 진단을 위한 면역 크로마토그래피 분석인 COVID19SEROSpeed IgM/IgG Rapid Test의 성능: 다기관 유럽 연구Multicenter Study Published on 2020-11-202022-09-10 Journal: Journal of Clinical Microbiology [Category] 진단, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed antibody antibody assay Antibody Response Autoimmune disorders chemiluminescence immunoassay clinical sensitivity clinical specificity Cohen’s kappa coefficient Concordance coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated diagnosis of SARS-CoV-2 diagnostic disease early stage early stages Efficiency enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay European evaluated exhibited FIVE highest IgM and IgG IgM/IgG immunoassay immunochromatographic assay Infection Kappa coefficient Kinetics multicenter N proteins New coronavirus overall concordance pandemic Paris Pasteur Institute Patient patients performance positive post-symptom onset presence of antibody PSO qRT-PCR Quantitative Rapid Rapid test respiratory reverse transcription-PCR SARS-CoV-2 SARS-COV-2 infection sera serology Seven severe acute respiratory syndrome Coronavirus specificity specimen specimens Symptomatic patients Test tested the antibody response the disease Viral viral infection viral infections [DOI] 10.1128/JCM.02240-20 PMC 바로가기 [Article Type] Multicenter Study
ICU admissions and in-hospital deaths linked to COVID-19 in the Paris region are correlated with previously observed ambient temperatureResearch Article Published on 2020-11-202022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Admission ambient association average Characteristics coronavirus disease correlated correlation COVID-19 Daily death deaths discrepancy ecological explain highest ICU ICU admission In-hospital death intensive care lockdown negative correlation Occurrence Paris Partial Pearson correlation coefficient severity statistically significant study period temperature time lag [DOI] 10.1371/journal.pone.0242268 PMC 바로가기 [Article Type] Research Article
A SARS-CoV-2 Surveillance System in Sub-Saharan Africa: Modeling Study for Persistence and Transmission to Inform PolicyOriginal Paper Published on 2020-11-192022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] addition African African COVID-19 surveillance system African COVID-19 transmission acceleration African COVID-19 transmission speed African econometrics African public health surveillance African SARS-CoV-2 African surveillance metrics Angola approach asymptomatic infections Benin Botswana Burkina Faso Burundi Cameroon Cape Central African Republic ChAd changes in Community Comoros Congo Contamination Cote d'Ivoire country COVID-19 COVID-19 7-day persistence COVID-19 case COVID-19 transmission COVID-19 transmission deceleration COVID-19 transmission jerk creating cumulative death decrease Democratic Republic of Congo dynamic panel data Equatorial Guinea Eritrea Ethiopia Evolution explain food insecurity Frame Gabon Gambia generalized method of the moments Ghana global COVID-19 surveillance Guinea Guinea-Bissau Health health system highest Identifier IMPROVE indicate Infection Infectious disease inherent Kenya lack Lesotho Liberia limit limitation lockdown madagascar Malawi Mali many case Mauritania Mauritius measure Metrics mitigate modeling morbidity Mortality Mozambique Namibia Niger Nigeria Novel coronavirus objective outbreak overcome pandemic persistence Policy Predictive Prevalence Prevent Public public health report Result Rwanda Sao Tome and Principe SARS-CoV-2 Senegal Seychelles Sierra Leone Somalia South Africa South Sudan SSA Standard statistical sub-Saharan Africa sub-Saharan African COVID-19 Sudan Suriname Surveillance Swaziland System Tanzania the disease the United State Togo Transmission Transmission model transmission rate treat Uganda variable Variation Zambia Zimbabwe [DOI] 10.2196/24248 PMC 바로가기 [Article Type] Original Paper
Covid-19 Mortality: A Matter of Vulnerability Among Nations Facing Limited Margins of AdaptationPublic Health Published on 2020-11-192022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] adaptation association component correlation country COVID-19 criteria death rate demography domain Environment Epidemic Evolution Factor fatality FIVE growth highest homogeneous Immunity IMPROVE Infectious disease Limited lockdown matter measure Mortality nation National niche adaptation Non-communicable disease Pandemia pandemic parameter Pearson correlation physical Prevalence principal public health Resilience retrieved Support temperature tested vulnerability [DOI] 10.3389/fpubh.2020.604339 PMC 바로가기 [Article Type] Public Health
Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers, and convalescent plasma donorsCOVID-19 환자, 의료 종사자 및 회복기 혈장 기증자의 SARS-CoV-2 급증에 대한 중화 항체Technical Advance Published on 2020-11-192022-09-12 Journal: JCI Insight [Category] SARS, 진단, [키워드] antibody Antibody testing Cellular immune response cohorts convalescent plasma COVID-19 COVID-19 pathogenesis COVID-19 patients COVID-19 symptoms Donor donors Efficacy evaluate followed by glycoprotein HCWs Health care Health care worker health care workers highest highlight HIV-1 hospitalized patients human antibody response ICU ICU Patients individual individuals intensive care intensive care unit intron lentiviral lentivirus Neutralization assay neutralizing antibody Neutralizing antibody titer neutralizing antibody titers Patient phenotypic phenotypic variation pseudotype pseudotyped Rapid reporter SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 spike SARS-CoV-2 strain secreted serological survey Serological surveys serum the SARS-CoV-2 Treatment Variation Virus neutralization was used [DOI] 10.1172/jci.insight.143213 PMC 바로가기 [Article Type] Technical Advance
International Survey to Establish Prioritized Outcomes for Trials in People With Coronavirus Disease 2019Clinical Investigations Published on 2020-11-182022-11-01 Journal: Critical Care Medicine [Category] COVID-19, SARS, [키워드] analyzed Anxiety Blood cardiovascular disease chest pain Chinese clinical trial Clinicians conducted content coronavirus coronavirus disease country Critical Critical care Digital English fatigue gastrointestinal problems generate groups Health highest Infection Italian knowledge life-threatening Likert scale lung median Mortality organ Organ failure outcome outcomes oxygen Pain participant patients Pneumonia professional professionals researchers Respiratory failure scale scarring Sepsis Shortness of breath Spanish survey their family members three group tolerable Trial trials Variability [DOI] 10.1097/CCM.0000000000004584 PMC 바로가기 [Article Type] Clinical Investigations