Registered Interventional Clinical Trials for Old Populations With Infectious Diseases on ClinicalTrials.gov: A Cross-Sectional StudyOriginal Research Published on 2020-06-262024-09-02 Journal: Frontiers in Pharmacology [Category] 대상포진, [키워드] clinical trial ClinicalTrials.gov Infectious disease Intervention old population [DOI] 10.3389/fphar.2020.00942 PMC 바로가기 [Article Type] Original Research
Social, ethical and behavioural aspects of COVID-19Study Protocol Published on 2020-06-252022-10-28 Journal: Wellcome Open Research [Category] COVID-19, [키워드] behavioural can be used clinical trial collecting data conducted country COVID-19 COVID-19 pandemic Data collection decision drug Ethics Evidence groups information initiated Intervention Italy lack limitation Malaysia Mathematical modelling mental health pandemic participant prevention of COVID-19 provided public health measure Qualitative Quantitative quarantine real time risk robust Self-isolation Slovenia social social distancing Thailand Travel Treatment United Kingdom [DOI] 10.12688/wellcomeopenres.15813.2 PMC 바로가기 [Article Type] Study Protocol
Pharmacotherapics Advice in Guidelines for COVID-19Pharmacology Published on 2020-06-242022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] China Chloroquine clinical trial coronavirus disease country COVID-19 drugs effective Efficacy and safety Germany guideline highlight indicated Italy Medicines National organization outbreak pharmacotherapy Pneumonia SARS-CoV-2 Tocilizumab treatment for COVID-19 [DOI] 10.3389/fphar.2020.00950 PMC 바로가기 [Article Type] Pharmacology
Class A G Protein-Coupled Receptor Antagonist Famotidine as a Therapeutic Alternative against SARS-CoV2: An In Silico AnalysisArticle Published on 2020-06-242022-10-28 Journal: Biomolecules [Category] COVID-19, [키워드] administration Analysis antagonist Antiviral antiviral drugs Antiviral effect antiviral therapy approach binding affinity catalytic site class clinical trial Combination computational analysis contribute COVID-19 described disease drug effective Effectiveness Famotidine G protein-coupled receptor Gastroesophageal reflux HIV HIV protease inhibitor Human immunodeficiency virus Hydroxychloroquine in silico indicated inhibitors intravenous involved knowledge outcome pandemic parameter Patient pharmacokinetic pharmacological protease Proteases provided reached Replication repurposing respiratory retrospective SARS-CoV2 SARS-CoV2 infection Scientific community the United State therapeutic therapy Treatment virus replication [DOI] 10.3390/biom10060954 PMC 바로가기 [Article Type] Article
Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019 The GRECCO-19 Randomized Clinical Trial코로나바이러스 질병 2019로 입원한 환자의 심장 및 염증성 바이오마커와 임상 결과에 대한 콜히친 대 표준 치료의 효과 GRECCO-19 무작위 임상 시험Research Published on 2020-06-242022-08-13 Journal: JAMA Network Open [Category] SARS, 임상, [키워드] 1:1 105 patient 105 patients 95% CI activity acute respiratory syndrome administration Adverse adverse events age all-cause mortality anti-inflammatory action biochemical C-reactive protein cardiac cardiac troponin caution clinical clinical benefit Clinical deterioration clinical end point Clinical outcome clinical outcomes clinical status clinical trial Colchicine colchicine group Complication Concentration control group coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death Deterioration diarrhea dimerized Effect effect of treatment efficacy analysis end point evaluate evaluate the effect evaluated event except for finding followed by global pandemic Greece groups hospital Hospitalized Identifier Importance increase in Infection Inflammatory biomarker intention-to-treat basis interquartile range Loading dose log rank maintenance dose measure mechanical ventilation median no difference no significant difference no significant differences normal activities objective Odds ratio Open-label participant Patient patients patients hospitalized plasma fragment D Point prevention primary end point Randomized randomized clinical trial receipt Registration Relevance respiratory Result safety profile secondary seriousness setting severity significant differences significantly Standard statistically survival survival time symptomatic took place treat Treatment treatment with colchicine Trial registration troponin was performed with COVID-19 [DOI] 10.1001/jamanetworkopen.2020.13136 PMC 바로가기 [Article Type] Research
Characteristics of the Coronavirus Disease 2019 and related Therapeutic OptionsArticle Published on 2020-06-242022-10-30 Journal: Molecular Therapy [Category] COVID-19, [키워드] acute respiratory syndrome affecting cause caused Characteristics Clinical symptoms clinical trial coronavirus disease Coronavirus-2 COVID-19 COVID-19 patients death rate Diagnosis effective feature Genome global pandemic Incubation period Infection molecular target option patients Pneumonia potential molecular provide Replication resulting SARS-CoV-2 SARS-COV-2 infection severe health problem suppress target therapeutic drug Treatment Vaccine development [DOI] 10.1016/j.omtm.2020.06.013 PMC 바로가기 [Article Type] Article
Therapeutic potential of mesenchymal stem cells and their exosomes in severe novel coronavirus disease 2019 (COVID-19) casesReview Published on 2020-06-222022-10-30 Journal: Inflammation and Regeneration [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome Affect anti-inflammatory macrophages ARDS B cells clinical study clinical trial coronavirus coronavirus disease country COVID-19 Cytokine storm dendritic cells Effect Exosome Exosomes health condition healthcare Immune cell induce initiated mechanism mesenchymal stem cell Mesenchymal stem cells MSC MSCs multiple organ failure Novel coronavirus novel coronavirus disease Registered Regulatory resolved SARS-CoV-2 SARS-COV-2 infection Severe case Spread stem cell syndrome T cells therapy Treatment Trial trials virus worldwide pandemic [DOI] 10.1186/s41232-020-00121-y PMC 바로가기 [Article Type] Review
Survey Says: “COVID-19 Lockdown Hits Young Faculty and Clinical Trials”Commentary Published on 2020-06-222022-10-04 Journal: Stem Cell Reports [Category] 임상, [키워드] “COVID-19 Cell clinical clinical trial Community COVID-19 faculty impacted investigators Laboratory Research researcher Society STEM Support survey [DOI] 10.1016/j.stemcr.2020.06.010 PMC 바로가기 [Article Type] Commentary
COVID 19 pandemic, status of clinical trials in Africa on May 2020: need to reinforce코로나19 대유행, 2020년 5월 아프리카 임상시험 현황: 강화 필요Letter to the Editors Published on 2020-06-222022-09-10 Journal: The Pan African Medical Journal [Category] MERS, 신약개발, 임상, [키워드] Africa clinical trial clinical trials COVID 19 COVID-19 pandemic [DOI] 10.11604/pamj.supp.2020.35.2.24349 PMC 바로가기 [Article Type] Letter to the Editors
Treatment and preliminary outcomes of 150 acute care patients with COVID-19 in a rural health system in the DakotasShort Paper Published on 2020-06-222022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, [키워드] Administered administration adverse effect arrhythmia Care clinical trial Cohort Community convalescent plasma coronavirus Corticosteroids COVID-19 disease severity Efficacy expired Healthcare system hospital hospital discharge hospitalised Hydroxychloroquine hydroxychloroquine plus azithromycin majority outcome outcomes Patient patients with COVID-19 pharmacological treatment Population QT interval regimen resource risk Rural health SARS-CoV-2 Spread subsequent survived therapeutic anticoagulation therapeutic option Tocilizumab treat treated Treatment [DOI] 10.1017/S0950268820001351 PMC 바로가기 [Article Type] Short Paper