A Double Triage and Telemedicine Protocol to Optimize Infection Control in an Emergency Department in Taiwan During the COVID-19 Pandemic: Retrospective Feasibility StudyOriginal Paper Published on 2020-06-232022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] 5-point Likert scale 95% CI benefit confounders Control coronavirus disease COVID-19 COVID-19 case COVID-19 pandemic Department disease Emergency emergency department evaluate evaluated feasibility Final Health health care workers high risk implementation IMPROVE in both group infection control mean score objective Patient patients physician Physicians Primary outcomes protocol question questionnaire recruited Result Retrospective study Secondary outcomes significantly significantly shorter Stress suggested Taiwan Telemedicine the mean the patient treated Triage university was used [DOI] 10.2196/20586 PMC 바로가기 [Article Type] Original Paper
Research methodology and characteristics of journal articles with original data, preprint articles and registered clinical trial protocols about COVID-19Research Article Published on 2020-06-222022-10-28 Journal: BMC Medical Research Methodology [Category] COVID-19, Fulltext, SARS, [키워드] analyzed article articles Case report Characteristics China Chinese Chloroquine clinical clinical trial Community coronavirus COVID-19 COVID-19 collection COVID-19 research disease Factor help heterogeneous Hydroxychloroquine Impact indicate Intervention journal limit majority mapping median methodology Original research outcome participant Participants Preprint Primary outcome protocol public health emergency Registered registry reported Research respond Result retrospective Retrospective study SARS-CoV-2 Sponsor Study design tested the WHO Trial trial protocol trials WHO WHO ICTRP World Health Organization [DOI] 10.1186/s12874-020-01047-2 PMC 바로가기 [Article Type] Research Article
Closing the Psychological Treatment Gap During the COVID-19 Pandemic With a Supportive Text Messaging Program: Protocol for Implementation and EvaluationProtocol Published on 2020-06-222022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] Analysis Anxiety baseline Canadians collected COVID-19 COVID-19 crisis Depression depressive depressive symptom Depressive symptoms disease distress E-mental health Endpoint evaluated Gap Generalized Health Identifier Impact include information Intervention maintain mental health Metrics mobile phones objective online questionnaire outcome pandemic Perceived Stress Scale physical distancing Practitioner Prevalence prevalence rate Primary outcome protocol Providing Psychological Psychological intervention reduce report Research Result Satisfaction SMS Spread Stress Support text Text4Hope threat virus [DOI] 10.2196/19292 PMC 바로가기 [Article Type] Protocol
Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II): protocol for an observational study using linked Scottish national dataInfectious Diseases Published on 2020-06-212022-10-28 Journal: BMJ Open [Category] COVID-19, Fulltext, SARS, [키워드] acute respiratory syndrome adverse events Analysis antimicrobial antimicrobial drug approval association attack rate Characteristics Committee coronavirus COVID-19 COVID-19 epidemic COVID-19 pandemic Cox model dataset death determine dissemination Effectiveness enhanced Epidemiology Ethics evaluate expand healthcare highest hospitalisation individual International Intervention Laboratory laboratory data MONITOR morbidity and mortality Mortality multivariate logistic regression National pandemic peer-reviewed platform Poisson regression models preventive intervention primary care Primary outcome prospective observational cohort protective effect protocol public health Registered required respiratory medicine (see thoracic medicine) risk SARS-CoV-2 SARS-COV-2 infection Scottish secondary outcome service Study design Surveillance therapeutic therapeutic intervention Therapies Vaccine [DOI] 10.1136/bmjopen-2020-039097 PMC 바로가기 [Article Type] Infectious Diseases
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-06-192022-10-29 Journal: Trials [Category] COVID-19, SARS, [키워드] 1:1 24 hour acute respiratory distress Administered administration Aerogen Aerogen Solo® Aerosols age airway alveolar alveolar injury anticipated ARDS backbone Berlin criteria blinded blocker Breastfeeding carrier cell-free DNA citrullinated histones clearance cleave Clinical practice clinical trial comparator Compound computer-generated consecutive patient control arm coronavirus 2 coronavirus disease COVID-19 COVID-19 patients criteria damage-associated molecular pattern DAMP DAMPs diagnosed with COVID-19 dissemination distal Dornase alfa dose double-stranded DSMB Efficacy element eliminated enteral nutrition Extracellular extracellular DNA fibrosis glycemic control hospital Hospitalized hospitals hyperinflammation hypersensitivity ICU Inclusion inclusion criteria induce Inflammation intensive care interim analysis Intervention Ireland less looser lung lung damage Lungs management mechanical ventilation mechanically ventilated patient monitoring board myeloperoxidase NET NETs neutrophil Neutrophil extracellular trap Neutrophil extracellular traps number objective Occurrence Open-label outcome PaO Paris participant Patient patients PEEP performed Pneumocytes Primary outcome progression Prone position Protective protocol randomisation randomised randomised controlled trial Randomized receive recruit recruitment reduce reducing Registered respiratory Roche Rothschild Sample size SARS-CoV-2 secretion Sedation Severe COVID-19 pneumonia severe pneumonia severity statistical analysis status study group Study protocol Switzerland syndrome to define Toxicity tracheal Treatment Trial usual care Ventilation vibrating mesh nebulizer Volume website [DOI] 10.1186/s13063-020-04488-8 PMC 바로가기 [Article Type] Letter
AGILE-ACCORD: A Randomized, Multicentre, Seamless, Adaptive Phase I/II Platform Study to Determine the Optimal Dose, Safety and Efficacy of Multiple Candidate Agents for the Treatment of COVID-19: A structured summary of a study protocol for a randomised platform trialAGILE-ACCORD: COVID-19 치료를 위한 여러 후보 약제의 최적 용량, 안전성 및 효능을 결정하기 위한 무작위, 다기관, 원활한, 적응 I/II상 플랫폼 연구: 무작위 플랫폼에 대한 연구 프로토콜의 구조화된 요약 재판Letter Published on 2020-06-192022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 9-point ordinal scale acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive added Adult patients Adverse adverse events agent Anti-viral treatment approval Bayesian Blinding candidate Candidates clinical Clinical improvement cloud Cohort cohorts Combination Common Terminology Criteria Community community setting comparator contributing to coronavirus COVID-19 COVID-19 infection CST cytokine cytokine release death defined determine disease dissemination dose EDC Efficacy Efficacy and safety element eligibility criteria eligible England EudraCT evaluated expected for inclusion futility GRADE group hospitalised hospitalised patient Hospitalization in some include Infection intubation Ireland laboratory-confirmed later phase limit Mask Master protocol mechanical ventilation mechanism mechanism of action multi-arm multicentre Multiple nasal prongs non-invasive ventilation North number objective open Open-label opens optimal dose Ordinal Scale organ Other outcome oxygen oxygen saturation oxygen) participant Patient patient population patients peripheral capillary Peripheral capillary oxygen saturation phase Phase I/II Placebo platform Platform study Platform trial Population Prevent progression of disease promise protocol randomisation randomised Rave recruited recruitment Regulatory required respiratory Safety Sample size SARS-CoV-2 SARS-COV-2 infection seamless setup severe acute respiratory syndrome Coronavirus severe disease shown SOC Specific Stage Standard Standard of care status Study protocol the WHO toxicities Toxicity Treatment treatment of COVID-19 Trial Trial registration Ventilation Viral Viral load viral replication website WHO working [DOI] 10.1186/s13063-020-04473-1 PMC 바로가기 [Article Type] Letter
Letter to the editor: efficacy of different methods of combination regimen administrations including dexamethasone, intravenous immunoglobulin, and interferon-beta to treat critically ill COVID-19 patients: a structured summary of a study protocol for a randomized controlled trialLetter Published on 2020-06-192022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 24 hours acute respiratory distress administration Admission age age and sex allergy ARDS Arm blinded Blood oxygen saturation can be used checked clinical coded Combination combination regimen Computed tomography conducted Contact Control control arm Corticosteroid Corticosteroids COVID-19 COVID-19 patients Critically ill Critically ill patient critically ill patients Cytokine storm develop Dexamethasone dissemination dosage dose drug early administration education Efficacy element eligible excessive inflammatory response experimental group Frequency generate group help hepatitis B HIV positive hospital Hospitalization hospitalized patient Hypothesis Immunoglobulin IMPROVE increase in Inflammation information Interferon-beta Intervention intervention group Intravenous immunoglobulin intubation investigator Iran laboratory technician less lung lung damage management mortality rate MOST number Nurses objective outcome Parallel Arm participant Patient patients Patients management percentage positive RT-PCR Pregnancy protocol random random number generator randomised randomised controlled trial randomization Randomized controlled trial Randomly RCT receive reduce Registration reported researcher respiratory rate Sample size severe COVID-19 Side effects Standard standard treatment statistical statistician study drug study group Study protocol subject supportive care syndrome the cytokine storm the WHO treat Treatment Trial website WHO guideline [DOI] 10.1186/s13063-020-04499-5 PMC 바로가기 [Article Type] Letter
Chinese medicine for COVID-19 A protocol for systematic review and meta-analysis3800 Published on 2020-06-192022-10-30 Journal: Medicine [Category] COVID-19, SARS, [키워드] 95% CIs 95% confidence interval adverse effect Analysis appear article Asia asymptomatic infection cause CBM Chest CT China Chinese Chinese medicine CIs CNKI Cochrane Library Consensus continuous variable Controlled trial Coronavirus disease 2019 COVID-19 database death disagreement disease East Efficacy Efficacy and safety Evidence Handbook hospitalised include Infrastructure journal literature mean difference Meta-analysis Mild Novel coronavirus Nucleic acid detection Odds ratio outbreak outcome participant Patient performed Placebo Pneumonia protocol recruited reported resolved Respiratory disease Respiratory failure Respiratory illness Respiratory samples Result review risk risk of bia Risk of bias SARS-COV-2 infection Science searched severe viral pneumonia Spread systematic review technique therapeutic agents treat Treatment upper respiratory tract variable VIP virus with COVID-19 Wuhan, China [DOI] 10.1097/MD.0000000000020660 PMC 바로가기 [Article Type] 3800
Efficacy and safety of Chinese patent medicine injection for COVID-19 A protocol for systematic review and meta-analysis6700 Published on 2020-06-192022-10-30 Journal: Medicine [Category] COVID-19, SARS, [키워드] abstracts attacked bias risk caused China Chinese Chinese patent medicine injection clinical symptom clinical trial Clinicians Cochrane Library Corona country COVID-19 database Deterioration Efficacy and safety Epidemic evaluate Evidence infection rate Infrastructure injection journal literature Meta-analysis outbreak Patient protocol provided Randomized controlled trial reducing researcher shown significant effect systematic review the disease Treatment virus infection Web of Science WHO World Health Organization [DOI] 10.1097/MD.0000000000020706 PMC 바로가기 [Article Type] 6700
Rapid Direct Nucleic Acid Amplification Test without RNA Extraction for SARS-CoV-2 Using a Portable PCR ThermocyclerArticle Published on 2020-06-182022-10-31 Journal: Genes [Category] COVID-19, SARS, [키워드] acid acute respiratory syndrome amplification caused coronavirus coronavirus disease country COVID-19 Diagnosis diagnostics Direct direct-PCR extraction homogeneous Laboratory molecular nasal Nucleic acid purification nucleocapsid pandemic PCR point-of-care polymerase chain portable PCR protocol Rapid reagents reduce Region Research respiratory sample reverse transcription RNA RNA copy RNA purification RT-PCR SARS-CoV-2 sputum Test thermocycler [DOI] 10.3390/genes11060664 PMC 바로가기 [Article Type] Article