What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocolObservational Study Published on 2021-03-102022-10-04 Journal: BMJ Open [Category] 임상, [키워드] acute COVID-19 acute phase affected Analysis approval can be used Care clinical Clinical management Cohort condition consequence COVID-19 Diagnosis dissemination Ethical approval Ethics facilitate Follow-up group hospital discharge hospitalisation hospitalisation with COVID-19 identify IMPROVE include indication Infectious diseases intensive care International ISARIC Italy Local Longitudinal data management multisite New Norway outcome Patient patients patients with COVID-19 physical Prevent protocol psychological support public health reduce rehabilitation reported respiratory responsible risk risk factor Russia Site South Africa Study protocol subset Symptom website WHO’ [DOI] 10.1136/bmjopen-2020-043887 PMC 바로가기 [Article Type] Observational Study
Adverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK BiobankOriginal Article Published on 2021-03-082022-10-28 Journal: Aging Clinical and Experimental Research [Category] COVID-19, MERS, SARS, [키워드] acute COVID-19 adjusted Admission Adverse Affect age alterations Arterial stiffness association baseline body mass index Cardiovascular Magnetic Resonance cardiovascular risk factors Care cholesterol classical coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 test COVID-19 testing Critical care death Deprivation diabetes died Fractions greater hospital hypertension independent indolent likelihood male multivariable logistic regression Myocardial infarction observational study Older participant phenotype Phenotypes positive Public Health England required Result severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Sex significantly higher smoking stroke supplementary material tested UK biobank ventricular Volume with COVID-19 [DOI] 10.1007/s40520-021-01808-z PMC 바로가기 [Article Type] Original Article
Longitudinal antibody repertoire in “mild” versus “severe” COVID-19 patients reveals immune markers associated with disease severity and resolutionComparative Study Published on 2021-03-052022-10-04 Journal: Science Advances [Category] SARS, 바이오마커, 진단, [키워드] acute COVID-19 Affinity maturation antibody affinity Antibody binding antibody marker antibody repertoire antigenic clinical disease coronavirus disease COVID-19 COVID-19 patient COVID-19 patients demonstrated disease severity effective epitope Evolution of SARS-CoV-2 faster fusion peptide IgA IgG immune marker immunodominant Immunoglobulin increase in knowledge Limited longitudinal maturation Mild Patient patients with COVID-19 prefusion RBD Receptor binding domain reveal SARS-COV-2 infection SARS-CoV-2 spike sequence severe COVID-19 [DOI] 10.1126/sciadv.abf2467 PMC 바로가기 [Article Type] Comparative Study
A case report of greater saphenous vein thrombosis in a patient with coronavirus (COVID-19) infectionCase Report Published on 2021-03-032022-10-28 Journal: Tropical Diseases, Travel Medicine and Vaccines [Category] COVID-19, [키워드] acute COVID-19 acute respiratory syndrome Blood blood vessel blood vessels Case report caused chills CLIA coronavirus Coronavirus infection cough COVID-19 CRP disease Doppler ultrasound Effect endothelial damage ESR Fever greater high risk hospital Hospitalized hypercoagulability Infection Iran Laboratory test LDH muscle aches Patient patient with COVID-19 pneumonia case SARS-CoV-2 Superficial vein thrombosis Symptom Tachycardia the patient thrombosis Ultrasonography virus WHO World Health Organization Wuhan, China [DOI] 10.1186/s40794-021-00131-9 PMC 바로가기 [Article Type] Case Report
Metabolic programs define dysfunctional immune responses in severe COVID-19 patients대사 프로그램은 중증 COVID-19 환자의 역기능 면역 반응을 정의합니다Article Published on 2021-02-262022-09-12 Journal: Cell Reports [Category] MERS, SARS, 진단, [키워드] Abstract accompanied acute COVID-19 anion Apoptosis caspase Cell channel Characteristics coronavirus disease COVID-19 COVID-19 patient develop disease disease severity Elderly patient Express functional highlight identify Immune cell immune response immunological immunology immunometabolism increase in increases in Infection inhibited lymphopenia MDSCs metabolic metabolic pathway metabolism Mild Mitochondria mitochondrial mitochondrial dysfunction myeloid cell observé oligomerization Patient phenotype Population predict provide regimens SARS-CoV-2 SARS-CoV-2 patient severe COVID-19 patient severe disease T cell T cells therapeutic therapeutic target these cell Thompson unique VDAC1 viral infections [DOI] 10.1016/j.celrep.2021.108863 PMC 바로가기 [Article Type] Article
T-Helper Cell Subset Response Is a Determining Factor in COVID-19 ProgressionObservational Study Published on 2021-02-262022-10-04 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, 임상, [키워드] accompanied activated acute COVID-19 acute phase analyzed association AUC Cell controls COVID-19 COVID-19 patient Cytokines death Department Determining Diagnosis died Disease progression elevated evaluated Factor flow cytometer Follow-up group groups hospital IL-10 IL-13 IL-15 IL-2 IL-6 immune response Immunity independent risk factor infections IP-10 lymphocyte Medicine organized outcome Patient percentage Phenotypes pro-inflammatory Prognosis Prospective Study recruited reduction response SARS-CoV2 senescent serum cytokine shown significant difference significantly higher T-helper Th2 Th2 cell Th2 response the disease the patient those who survived viral infection was obtained [DOI] 10.3389/fcimb.2021.624483 PMC 바로가기 [Article Type] Observational Study
Challenges in Managing Pericardial Disease Related to Post Viral Syndrome After COVID-19 InfectionCardiology Published on 2021-02-202022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute COVID-19 acute infection arrhythmia Cardiac tamponade challenge Clinical course Colchicine complication of COVID-19 coronavirus disease Course COVID-19 COVID-19 infection disease etiology Infection initial managing MOST Myocardial ischemia myocarditis non-steroidal anti-inflammatory drug NSAIDS Patient patients pericardial disease post viral syndrome reported Respiratory illness Steroids therapeutic therapy viral pericarditis [DOI] 10.7759/cureus.13461 PMC 바로가기 [Article Type] Cardiology
Prevalence and Determinants of Fatigue after COVID-19 in Non-Hospitalized Subjects: A Population-Based StudyArticle Published on 2021-02-192022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] 95% CI acute COVID-19 acute phase analyzed CFQ-11 Confusion COVID-19 defined determinant fatigue General population Linear regression analysis Logistic median Mental multivariable Patient physical population-based cohort positive PCR post-infectious fatigue Post-viral fatigue Prevalence prevalent questionnaire reported SARS-CoV-2 Sex subject Symptom women [DOI] 10.3390/ijerph18042030 PMC 바로가기 [Article Type] Article
Vaccine Hesitancy among Italian Patients Recovered from COVID-19 Infection towards Influenza and Sars-Cov-2 VaccinationArticle Published on 2021-02-182022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute COVID-19 acute respiratory syndrome age being carried Cohort coronavirus coronavirus disease COVID-19 cross-sectional Factor female First wave flu Hesitancy Hospitalized Influenza Italian Italy majority median age mild illness multifactorial pandemic participated performed positive attitude recovered recovered patients SARS-CoV-2 SARS-CoV-2 vaccine vaccination Vaccine hesitancy Vaccines [DOI] 10.3390/vaccines9020172 PMC 바로가기 [Article Type] Article
Impact of COVID-19 on the Speech and Language Therapy Profession and Their PatientsNeurology Published on 2021-02-182022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] acute COVID-19 affected affecting Analysis analyzed approach benefit Care change college COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients database disruption theory Dysphagia flexible healthcare service Impact information Intervention language Language Therapy less outcome outcome measurement outcomes pandemic Patient patients patients with COVID-19 positive profession provided question receiving reduction in Referral response routine clinical data service provision speech speech and language therapy supported therapist therapy triggered usual care was used [DOI] 10.3389/fneur.2021.629190 PMC 바로가기 [Article Type] Neurology