The Current Evidence Regarding COVID-19 and Pregnancy: Where Are We Now and Where Should We Head to Next?Review Published on 2021-10-052022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] adverse effect available data Breastfeeding Care Characteristics clinical manifestation Complication complications Course COVID-19 Critical current database delivery developmental head Health involved Neonatal neonatal health outbreak pandemic plethora poor quality Pregnancy pregnant patient reported Research risk SARS-CoV-2 Transmission vaccination Vaccination strategy Viral transmission Volume was performed [DOI] 10.3390/v13102000 PMC 바로가기 [Article Type] Review
Internal Bleeding Extending to the Retroperitoneum and Right Psoas With Severe Acute Respiratory Syndrome Coronavirus 2 InfectionInternal Medicine Published on 2021-10-042022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome added adverse effect Anticoagulants anticoagulation bleeding Blood Case report Coagulopathy complications of anticoagulation coronavirus coronavirus 2 Coronavirus disease 2019 COVID-19 COVID-19 associated coagulopathy COVID-19 patients Critically ill dose healthy hemoglobin ICU IMPROVE Infection internal Intervention Jehovah jehovah's witness knowledge management mechanical ventilation outcomes Patient potential risk protocol respiratory retroperitoneal bleed Retroperitoneum right risk SARS-CoV-2 severe COVID-19 therapy Thromboembolic event thrombosis weighed witness [DOI] 10.7759/cureus.18477 PMC 바로가기 [Article Type] Internal Medicine
Adverse Effects of Metformin From Diabetes to COVID-19, Cancer, Neurodegenerative Diseases, and Aging: Is VDAC1 a Common Target?Physiology Published on 2021-10-042022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] addition Adverse adverse effect Apoptosis Apoptotic cell death Cancer cancers cardiovascular diseases Cell cell death Characteristics common Control COVID-19 death Diabetes Mellitus Diabetic diabetic patients disease Diseases drug candidate Effect energy metabolism gut microbiota Hexokinase include Inflammation inhibiting Kidney disease metabolism metformin Mitochondria mitochondrial dysfunction neurodegenerative obesity opposite other disease question renal shown VDAC VDAC1 [DOI] 10.3389/fphys.2021.730048 PMC 바로가기 [Article Type] Physiology
Effectiveness of expiratory technique and induced sputum in obtaining good quality sputum from patients acutely hospitalized with suspected lower respiratory tract infection: a statistical analysis plan for a randomized controlled trialRandomized Controlled Trial Published on 2021-10-022022-10-04 Journal: Trials [Category] MERS, 임상, [키워드] adverse effect Analysis Antibiotics Clinical practice collected Culture Data analysis data-driven database dependent on Diagnosis expiratory Forced expiratory technique good quality Gram stain Hospitalized Hypothesis Induced sputum intention-to-treat intervention group knowledge Lower respiratory tract non-inferiority Patient Pneumonia Pragmatic protocol Randomized Randomized controlled trial recruitment reproducibility respiratory infection respiratory tract infection sputum Sputum sample statistical analyses statistical analysis Statistical analysis plan Study design submitted suction supplementary material tracheal Tracheal suction Treatment Trial usual care group [DOI] 10.1186/s13063-021-05639-1 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Impact of COVID-19 on Access to HIV Prevention Services Among Opioid-Dependent Individuals오피오이드 의존 개인의 HIV 예방 서비스 이용에 대한 COVID-19의 영향Article Published on 2021-10-012022-09-11 Journal: Journal of community health [Category] SARS, 치료제, [키워드] access adverse effect adverse effects Appointment appointments Blood change changed COVID-19 COVID-19 pandemic difficulty disorder doctor drug enrolled equipment HIV HIV prevention HIV testing identify Impact individual Infection injection lab majority medication Methadone opioid Opioid use disorder participant People who inject drugs pre-exposure prophylaxis PrEP prevention Prophylaxis reduce reduced reported service sexually transmitted infection transmitted Treatment utilization with HIV [DOI] 10.1007/s10900-021-00979-0 PMC 바로가기 [Article Type] Article
The impact of COVID-19 pandemic on AMI and stroke mortality in Lombardy: Evidence from the epicenter of the pandemicResearch Article Published on 2021-10-012022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 30-Day mortality adverse effect approaches Brescia candidate Care Clinical management COVID-19 COVID-19 pandemic Emergency Epidemic Evidence expected mortality Factor finding First wave healthcare hospital hospital management Hospitalization impacted implementation in-hospital mortality in-hospital mortality rate Italy Mortality mortality rate onset of symptom outbreak pandemic Patient patients preliminary evidence primary end-point provide provided robust significantly increased state statistically Stress stroke [DOI] 10.1371/journal.pone.0257910 PMC 바로가기 [Article Type] Research Article
Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunityResearch Article Published on 2021-10-012022-10-30 Journal: The Journal of Biological Chemistry [Category] COVID-19, SARS, [키워드] ACE2, angiotensin-converting enzyme II adverse effect antibody approach BCA, bicinchoninic acid BLI, bioluminescent imaging can be used Cationic lipid CDM, chemically defined media Cell cellular characterized COVID19 CTCS, clarified tissue culture supernatant CVS, concentrated vesicle suspension DOPE, dioleoyl phosphatidylethanolamine dose DOTAP, dioleoyl-3-trimethylammonium propane DTZ, diphenylterazine elicited encapsulation ER, endoplasmic reticulum EV, extracellular vesicle Evidence Exosome Exosomes Extracellular vesicles form functional had no human cell Humoral response HUVEC, human umbilical vein endothelial cell immunogenic induce injection Lipid nanoparticle lipofection LNP LNP, Lipid Nanoparticle long-lasting luciferase expression mice mRNA NTA, nanoparticle tracking analysis nucleocapsid ORF, open reading frame pfPBS, particle-free PBS previous study Protein repeated responses Safe SARS-CoV-2 immunity SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SEC, size-exclusion chromatography Skeletal muscle spike sustained T-cell tested the SARS-CoV-2 tissue Toxicity vitreous fluid [DOI] 10.1016/j.jbc.2021.101266 PMC 바로가기 [Article Type] Research Article
Possible Male Reproduction Complications after Coronavirus PandemicReview Article Published on 2021-09-292022-10-31 Journal: Cell Journal (Yakhteh) [Category] COVID-19, [키워드] ACE2 adverse effect Affect alteration Analysis angiotensin-converting enzyme 2 article Complication Coronavirus disease 2019 COVID-19 Evidence expressed Fertility Google Scholar Health hormone Impact Infection Luteinizing Hormone male male gonad male gonads male reproduction men organs parameters patients performed raised reported reproduction reproductive SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor Semen semen sample severe respiratory disease Sex hormones suggested the SARS-CoV-2 tissue various tissue Viral RNA virus [DOI] 10.22074/cellj.2021.7982 PMC 바로가기 [Article Type] Review Article
Safety, Immunogenicity, and Efficacy of COVID-19 Vaccines in Children and Adolescents: A Systematic ReviewSystematic Review Published on 2021-09-292022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adolescents adverse effect BNT162b2 Case series chest pain children China clinical Clinical studies clinical study CNKI common adverse events conducted CoronaVac COVID-19 COVID-19 vaccination COVID-19 vaccine database Efficacy eight fatigue follow-up time greater headache highest ICTRP identify immune response immunogenicity Infrastructure injection injection site investigated MONITOR myocarditis of BNT162b2 ongoing trials Pain Protective protective effect RCT RCTs registry reported review Safety safety profile Sample size searched systematic review Vaccine variety Web of Science WHO [DOI] 10.3390/vaccines9101102 PMC 바로가기 [Article Type] Systematic Review
Toxoplasmosis is a risk factor for acquiring SARS-CoV-2 infection and a severe course of COVID-19 in the Czech and Slovak population: a preregistered exploratory internet cross-sectional studyResearch Published on 2021-09-282022-10-28 Journal: Parasites & Vectors [Category] COVID-19, [키워드] Abstract adverse effect Affect age Autoimmunity cat chronic obstructive correlation Course COVID COVID-19 cross-sectional Diseases Effect exhibiting exploratory Factor Health higher risk immunodeficiency incidence individual infected individual Infection Latent likelihood Male sex Mental participant pets physical problem proximal public health pulmonary disease Result risk risk factor Risk factors risk of infection SARS-CoV-2 SARS-COV-2 infection severity Sex shown significantly higher subset Symptoms Toxoplasma Toxoplasma gondii toxoplasmosis transmission of SARS-CoV-2 vaccination was performed zoonosis [DOI] 10.1186/s13071-021-05021-9 PMC 바로가기 [Article Type] Research