Performance of the COVID19SEROSpeed IgM/IgG Rapid Test, an Immunochromatographic Assay for the Diagnosis of SARS-CoV-2 Infection: a Multicenter European StudySARS-CoV-2 감염 진단을 위한 면역 크로마토그래피 분석인 COVID19SEROSpeed IgM/IgG Rapid Test의 성능: 다기관 유럽 연구Multicenter Study Published on 2020-11-202022-09-10 Journal: Journal of Clinical Microbiology [Category] 진단, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed antibody antibody assay Antibody Response Autoimmune disorders chemiluminescence immunoassay clinical sensitivity clinical specificity Cohen’s kappa coefficient Concordance coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated diagnosis of SARS-CoV-2 diagnostic disease early stage early stages Efficiency enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay European evaluated exhibited FIVE highest IgM and IgG IgM/IgG immunoassay immunochromatographic assay Infection Kappa coefficient Kinetics multicenter N proteins New coronavirus overall concordance pandemic Paris Pasteur Institute Patient patients performance positive post-symptom onset presence of antibody PSO qRT-PCR Quantitative Rapid Rapid test respiratory reverse transcription-PCR SARS-CoV-2 SARS-COV-2 infection sera serology Seven severe acute respiratory syndrome Coronavirus specificity specimen specimens Symptomatic patients Test tested the antibody response the disease Viral viral infection viral infections [DOI] 10.1128/JCM.02240-20 PMC 바로가기 [Article Type] Multicenter Study
A predictive model for the severity of COVID-19 in elderly patientsResearch Paper Published on 2020-11-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] 95% confidence interval Admission albumin assigned benefit Cohort Concordance coronavirus disease COVID-19 COVID-19 patients Critical decision curve analysis demonstrated develop effective elderly Elderly patient elderly patients facilitate Fatality rate groups Hospitalization medical resource nomogram Odds ratio outcome Patient Pneumonia predict Predictive predictor predictors progressed reduce risk severity severity of COVID-19 significantly supportive care two group validation cohort [DOI] 10.18632/aging.103980 PMC 바로가기 [Article Type] Research Paper
Brief comparative evaluation of six open one-step RT-qPCR mastermixes for the detection of SARS-CoV-2 RNA using a Taqman probeTaqman 프로브를 사용한 SARS-CoV-2 RNA 검출을 위한 6개의 개방형 1단계 RT-qPCR 마스터믹스에 대한 간략한 비교 평가Comparative Study Published on 2020-11-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 치료기술, 치료제, [키워드] (Promega) (RdRp ABI 7500 acute respiratory syndrome coronavirus Applied Biosystems clinical laboratories Concordance coronavirus coronavirus 2 Ct value Ct values emerging virus exhibiting FIVE France Invitrogen Laboratory Laboratory-developed assay master mix New England Biolabs open pandemic percentage percentages Promega qPCR qRT-PCR RdRP reagent reagents reference respiratory respiratory specimen respiratory specimens RNA RNA polymerase RNA virus Roche RT-PCR kit RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shortage of reagent step System Takara TaqMan TaqMan probe thermocycler Universal Viral Viral RNA was tested [DOI] 10.1016/j.jcv.2020.104636 PMC 바로가기 [Article Type] Comparative Study
A comparison of health care worker-collected foam and polyester nasal swabs in convalescent COVID-19 patientsResearch Article Published on 2020-10-272022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] average Care collected Combination Concordance convalescent COVID-19 patient correlated cycle threshold Health in viral media nasal swab polyester sensitivity Swab threshold Transport media Viral load VTM [DOI] 10.1371/journal.pone.0241100 PMC 바로가기 [Article Type] Research Article
Exploiting an early warning Nomogram for predicting the risk of ICU admission in patients with COVID-19: a multi-center study in ChinaOriginal Research Published on 2020-10-272022-10-29 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] COVID-19, MERS, SARS, [키워드] addition age C-index calibration plot China Chronic kidney disease Clinical characteristics clinically Cohort collected Community Concordance coronavirus disease Coronavirus disease 2019 COVID-19 decision curve analysis demonstrated develop early warning evaluated external validation Fever global public health Health Hospital admission ICU ICU admission intensive care laboratory-confirmed Logistic regression nomogram novel operator Patient patients with COVID-19 predict prediction Randomly resources respiratory rate Result risk smoking status Systolic blood pressure validation cohort were used Wuhan [DOI] 10.1186/s13049-020-00795-w PMC 바로가기 [Article Type] Original Research
Frequency and Duration of SARS-CoV-2 Shedding in Oral Fluid Samples Assessed by a Modified Commercial Rapid Molecular AssayArticle Published on 2020-10-202022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] 95 % CI analysed analytical sensitivity BAL Bronchoalveolar lavage collected Concordance condition correlation COVID-19 COVID-19 diagnosis detect diagnosis and monitoring diagnosis of SARS-CoV-2 Direct direct assay Duration elevated gold standard high correlation Hospitalized Infection nasopharyngeal NPs oral oral fluid Prolonged Rapid real time RT-PCR RT-PCR Sample SARS-CoV-2 SARS-CoV-2 RNA Sensitivity and specificity severe COVID-19 shedding specimen Swab symptoms onset transmitted Viral load Viral RNA shedding virus was used [DOI] 10.3390/v12101184 PMC 바로가기 [Article Type] Article
Comparison of a rapid immunochromatographic test with a chemiluminescence immunoassay for detection of anti-SARS-CoV-2 IgM and IgGShort Communication Published on 2020-10-152022-10-27 Journal: Biochemia Medica [Category] COVID-19, [키워드] 2019-nCoV addition anti-SARS-CoV-2 IgM antibodies automated BSS calculated characterized chemiluminescence chemiluminescence immunoassay China CLIA Cohen Kappa index Cohen’s kappa coefficient Concordance COVID-19 disease Engineering Epidemiologic surveillance epidemiological purposes evaluate France global public health IgG IgG SARS-CoV-2 antibody IgM IgM and IgG IgM SARS-CoV-2 antibodies IgM/IgG immunoassay immunochromatographic immunochromatographic assay immunochromatographic test immunochromatography infected patients lateral flow likelihood ratio material New pandemic Patient PCR-confirmed diagnosis positive rapid assay rapid assays representing Result SARS-CoV-2 antibody serological test serum sample Shenzhen SNIBE Surveillance were measured [DOI] 10.11613/BM.2020.030901 PMC 바로가기 [Article Type] Short Communication
Comparison of a rapid immunochromatographic test with a chemiluminescence immunoassay for detection of anti-SARS-CoV-2 IgM and IgGShort Communication Published on 2020-10-152022-10-27 Journal: Biochemia Medica [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] 2019-nCoV addition anti-SARS-CoV-2 IgM antibodies automated BSS calculated characterized chemiluminescence chemiluminescence immunoassay China CLIA Cohen Kappa index Cohen’s kappa coefficient Concordance COVID-19 disease Engineering Epidemiologic surveillance epidemiological purposes evaluate France global public health IgG IgG SARS-CoV-2 antibody IgM IgM and IgG IgM SARS-CoV-2 antibodies IgM/IgG immunoassay immunochromatographic immunochromatographic assay immunochromatographic test immunochromatography infected patients lateral flow likelihood ratio material New pandemic Patient PCR-confirmed diagnosis positive rapid assay rapid assays representing Result SARS-CoV-2 antibody serological test serum sample Shenzhen SNIBE Surveillance were measured [DOI] 10.11613/BM.2020.030901 PMC 바로가기 [Article Type] Short Communication
Analytical and Clinical Validation for RT-qPCR Detection of SARS-CoV-2 Without RNA ExtractionMedicine Published on 2020-10-152022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] amplification automated buffer clinical clinical decision clinical impact Concordance condition Contagion COVID-19 COVID-19 pandemic Cq value detection Diagnosis diagnostic direct RT-qPCR evaluated extraction include Laboratory limit limit of detection Nasopharyngeal swab pandemic (COVID-19) Prospective protocol RNA RNA extraction RT-qPCR Safe SARS-CoV-2 SARS-CoV-2 RNA selected Shock shortage of reagent validation was selected widespread [DOI] 10.3389/fmed.2020.567572 PMC 바로가기 [Article Type] Medicine
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19Article Published on 2020-10-152022-10-04 Journal: Nature Communications [Category] MERS, SARS, 신약개발, 임상, 진단, 치료법, 치료제, [키워드] A549 cell anti-infective drug anti-infective drugs Antiviral antivirals approved can be used Cell culture clinically Concentration Concordance coronavirus coronavirus disease COVID-19 evaluate expressing facilitate High-throughput screening human ACE2 receptor identify inactive Infection inhibitor neutralization neutralizing antibody patient sera plaque reduction neutralization platform PRNT replicate SARS-CoV-2 selective Serological testing severe respiratory syndrome Vaccine wild-type virus [DOI] 10.1038/s41467-020-19055-7 PMC 바로가기 [Article Type] Article