The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implicationsArticle Published on 2022-08-312022-11-15 Journal: Biochemical Journal [Category] 진단, [키워드] activities amyloid microclots antioxidants biochemical burst Capillaries cell activation conditions COVID disease element Evidence explain hyperinflammation hypoxia implication Inflammatory diseases initiated Injury involved ischaemia–reperfusion injury. Long Long COVID malaise marker mechanism mechanisms metabolite Occurrence oxidative stress pathology produced reactive oxygen specy relapsing reperfusion rheumatoid arthritis Safe therapeutic Therapeutic benefit variety [DOI] 10.1042/BCJ20220154 PMC 바로가기
Selective Electrochemical Detection of SARS-CoV-2 Using Deep LearningArticle Published on 2022-08-302022-11-15 Journal: Viruses [Category] SARS, 치료기술, [키워드] Accuracy against SARS-CoV Algorithm applied approach collected Convolution CoV COVID COVID deep learning COVID-19 COVID-19 diagnosis dataset deep deep learning detect detection diagnose Diagnosis diagnostic different algorithms differential diagnosis electrochemical biosensor. electrochemical SARS-CoV-2 detection Human identify Infection investigated learning machine MERS-CoV Rapid antigen tests reduce reducing SARS-CoV-2 sensitivity specificity These data virus sample was used [DOI] 10.3390/v14091930 PMC 바로가기
Sentinel Cards Provide Practical SARS-CoV-2 Monitoring in School SettingsArticle Published on 2022-08-302023-07-09 Journal: mSystems [Category] COVID19(2023년), [키워드] COVID environmental sampling public health qPCR SARS-CoV-2 viral persistence [DOI] 10.1128/msystems.00109-22 PMC 바로가기
Implementation of Practical Surface SARS-CoV-2 Surveillance in School SettingsArticle Published on 2022-08-302023-07-09 Journal: mSystems [Category] COVID19(2023년), [키워드] COVID environmental sampling public health qPCR SARS-CoV-2 [DOI] 10.1128/msystems.00103-22 PMC 바로가기
A Bacteriophage-Based, Highly Efficacious, Needle- and Adjuvant-Free, Mucosal COVID-19 VaccineArticle Published on 2022-08-302022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] addition adenovirus-based Administered administration ambient Antibody titer bacteriophage CRISPR engineering bacteriophage T4 mucosal platform BALB/c broad immunity to SARS-CoV-2 variants bronchoalveolar lavage specimen bronchoalveolar lavage specimens caused CD4 CD8 Cell-mediated immune responses cellular immune responses Complete COVID COVID-19 CRISPR cytokine death delta variant dose drug effective elicited enzyme Epidemic exhibited exterior food generate globe gut microbiota hACE2 humoral Immunity induce Infection injected interior intramuscularly intranasal intranasally lung lesion mice mouse-adapted SARS-CoV-2 mRNA mucosal nasal needle needle-free intranasal vaccine not affect nucleocapsid protein omicron other respiratory infection pandemic Pathogens phage T4 platform predicted Prevent provide provided response responses robust SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants secretory IgA sera spike sterilizing immunity. T cell temperature the United State the vaccine Transgenic mouse Transmission trimer Vaccine variants Viral transmission Virus neutralization virus-neutralizing antibody World Health Organization [DOI] 10.1128/mbio.01822-22 PMC 바로가기
Impact of the COVID-19 pandemic on breastfeeding in Israel: a cross- sectional, observational surveyObservational Study Published on 2022-08-262022-10-05 Journal: International Breastfeeding Journal [Category] 임상, [키워드] 95% CI adjusted affected age asked Breastfeeding changes in collected data COVID COVID-19 COVID-19 pandemic cross cross-sectional demonstrated determine Effect expected extension Facebook Factor Factors Government group help highest hospital Impact lactation lockdown lockdowns Logistic regression analysis MOST mother mothers multivariate national health authority Newborns pandemic Panic participated receiving reported Stress was performed women [DOI] 10.1186/s13006-022-00505-5 PMC 바로가기 [Article Type] Observational Study
Clinical Performance of a Standardized Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Interferon-γ Release Assay for Simple Detection of T-Cell Responses After Infection or Vaccination감염 또는 백신 접종 후 T-세포 반응의 간단한 검출을 위한 표준화된 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 인터페론-γ 방출 분석의 임상 성능Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, 치료기술, [키워드] 19 2 95% confidence interval Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 best Cell cell response Chain Reaction clinical convalescent Convalescent patients coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 CoV COVID COVID-19 dependent on detection disease severity Euroimmun evaluated Follow-up Germany healthy IFN-γ IFN-γ response IFN-γ responses IGRA immune response individual Infection interferon interferon-γ magnitude Mild disease mild infections Neutralizing antibodies neutralizing antibody Patient performance polymerase chain reaction positive Primary infection Prospective Study Quantitative reference standard Release respiratory response reverse transcription Reverse transcription-polymerase chain reaction SARS SARS-CoV-2 SARS-COV-2 infection sensitivity serological serological test Serological tests serology severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 severity severity of illness simple specificity subject subjects T T-cell T-cell Response uninfected vaccination was measured Whole blood with mild disease γ release assay. [DOI] 10.1093/cid/ciab1021 PMC 바로가기 [Article Type] Article
Universal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Testing for Obstetric Inpatient Units Across the United States미국 전역의 산과 입원 환자 병동에 대한 보편적 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 검사Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술, [키워드] Act acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered Asymptomatic asymptomatic infection rate collected Community community infection coronavirus coronavirus 2 correlation Correlation analysis COVID COVID-19 cross-sectional cross-sectional study group Health health center healthcare hospital hospitals Infection infection rates Inpatient New North Obstetric Patient positive positive correlation Pregnancy pregnant Prevalence reported resource respiratory Rhode Island SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test SARS-CoV-2 testing SARS-CoV-2 tests Screening state Testing the United State unit United States Universal Utah Washington while [DOI] 10.1093/cid/ciab955 PMC 바로가기 [Article Type] Article
The Impact of Prior Infection and Age on Antibody Persistence After Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine중증 급성 호흡기 증후군 코로나바이러스 2 메신저 RNA 백신 후 항체 지속성에 대한 이전 감염 및 연령의 영향Article Published on 2022-08-242022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, [키워드] 19 2 acute respiratory syndrome affected age Antibody Response booster coronavirus coronavirus 2 CoV COVID Critical Determining environmental factor Genetic Immunity immunization Impact magnitude messenger Messenger RNA persistence respiratory RNA SARS SARS-CoV-2 SARS-COV-2 infection the antibody response the SARS-CoV-2 the timing vaccination Vaccine [DOI] 10.1093/cid/ciab850 PMC 바로가기 [Article Type] Article
Real-World Effectiveness of Remdesivir in Adults Hospitalized With Coronavirus Disease 2019 (COVID-19): A Retrospective, Multicenter Comparative Effectiveness Study코로나바이러스 질병 2019(COVID-19)로 입원한 성인에서 렘데시비르의 실제 효과: 후향적, 다기관 비교 효과 연구Multicenter Study Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료제, [키워드] 19 2 28-day mortality 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted hazard ratio Clinical improvement Comparative Control controls coronavirus coronavirus disease Coronavirus disease 2019 CoV COVID COVID-19 COVID-19 patients death Diagnosis dose Effectiveness healthcare Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients ICD-10 individual less likelihood low-flow oxygen male median age Mortality oxygen Patient patients Positive test Primary outcome real recipient Remdesivir retrospective routine SARS SARS-CoV-2 secondary outcome severe acute respiratory syndrome Coronavirus severely ill patient significantly significantly more Support symptomatic the United State Therapeutics Treatment United States unlikely world effectiveness. [DOI] 10.1093/cid/ciab1035 PMC 바로가기 [Article Type] Multicenter Study