diagnostic test – Page 23 – Communicable Diseases Research

A SARS-CoV-2 Nucleocapsid Variant that Affects Antigen Test Performance

항원 테스트 성능에 영향을 미치는 SARS-CoV-2 뉴클레오캡시드 변이체

Article

Published on 2021-08-012022-09-11
Journal: Journal of Clinical Virology [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법,

Serum antibody response to BNT162b2 after natural SARS‐CoV‐2 infection

천연 SARS-CoV-2 감염 후 BNT162b2에 대한 혈청 항체 반응

Observational Study

Published on 2021-08-012022-09-11
Journal: European Journal of Clinical Investigation [Category] MERS, SARS, 임상, 진단, 치료법,

[키워드] antibody antibody levels Antibody Response assumption benefit BNT162b2 BNT162b2 vaccine diagnostic test diagnostic tests DiaSorin dose Evidence first dose groups immunoassay in vitro individual Infection inhibition activity naïve individual naïve individuals neutralization test of BNT162b2 overlap Pfizer/BioNTech preliminary evidence receiving remained Research response Result Roche S1/S2 SARS‐CoV‐2 infection SARS‐CoV‐2 second dose serology seronegative seropositive significantly higher single dose Spike protein statistically significant stimulate supported surrogate virus neutralization test sVNT tested vaccination vaccination schedule Viral viral spike protein virus neutralization test
[DOI] 10.1111/eci.13632 PMC 바로가기 [Article Type] Observational Study

SARS-CoV-2 antibody response dynamics and heterogeneous diagnostic performance of four serological tests and a neutralization test in symptomatic healthcare workers with non-severe COVID-19

중증이 아닌 COVID-19를 가진 증상이 있는 의료 종사자를 대상으로 한 4가지 혈청 검사 및 중화 검사의 SARS-CoV-2 항체 반응 역학 및 이종 진단 성능

Observational Study

Published on 2021-08-012022-09-11
Journal: Journal of Clinical Virology [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] aims antibody Antibody Response Bio-rad Chain Reaction COVID-19 COVID-19 patient detectable detection rate diagnostic diagnostic test ELISA ELISAs enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays Euroimmun evaluated Genscript HCW HCWs healthcare worker Healthcare workers heterogeneous heterogenous highest hospital infected individuals Infection initial moment MOST neutralization neutralization test Neutralizing observational study PCR PCR-confirmed polymerase chain polymerase chain reaction positive presence of antibody prospective observational study Re-infection Re-infections remained SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 infected individuals SARS-COV-2 infection serological test serology seropositive serum serum sample serum samples study inclusion surrogate virus neutralization test sVNT symptomatic symptomatic individual the antibody response Variability virus neutralization test was performed
[DOI] 10.1016/j.jcv.2021.104904 PMC 바로가기 [Article Type] Observational Study

High-Throughput Multiplex SARS-CoV-2 IgG Microsphere Immunoassay for Dried Blood Spots: A Public Health Strategy for Enhanced Serosurvey Capacity

건혈 반점에 대한 고처리량 멀티플렉스 SARS-CoV-2 IgG 미소구체 면역분석: 혈청 조사 능력 향상을 위한 공중 보건 전략

Research Article

Published on 2021-07-282022-09-10
Journal: Microbiology Spectrum [Category] SARS, 변종, 진단, 치료기술, 치료법,

[키워드] 384-well plate acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed antibody Antibody test antibody tests Antigen antigens Asymptomatic individuals automated Blood Capacity categories collected conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Decision making demonstrated detect diagnostic diagnostic test diagnostic testing dried blood spot Dried blood spots early phase enhanced estimate fluorescence intensity Health care Health care worker IgG IgG antibodies IgG antibody immunoassay immunoassays invasive laboratory-confirmed SARS-CoV-2 infection MFI MIA microsphere modify multiplex New York nucleocapsid pandemic populations positive correlation Positive test Prevalence prevalence of COVID-19 Public public health R 2 ranged respiratory resulting robust SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody response SARS-CoV-2 antibody responses SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 protein SARS-CoV-2 proteins sensitivity sera serology Seroprevalence Serosurvey Serosurveys serum severe acute respiratory syndrome Coronavirus significantly higher specificity spring state Strategy stratified subunit Symptom symptom data symptomatic Testing the SARS-CoV-2 Vaccines validation study variant variety
[DOI] 10.1128/Spectrum.00134-21 PMC 바로가기 [Article Type] Research Article

Whole Blood Interferon γ Release Is a More Sensitive Marker of Prior Exposure to Coxiella burnetii Than Are Antibody Responses

Original Research

Published on 2021-07-282023-05-31
Journal: Frontiers in Immunology [Category] Fulltext, 조류인플루엔자,

[키워드] Biomarker Coxiella burnetii diagnostic test exposure Human interferon gamma Q fever T-cell
[DOI] 10.3389/fimmu.2021.701811 PMC 바로가기 [Article Type] Original Research

Minute-scale detection of SARS-CoV-2 using a low-cost biosensor composed of pencil graphite electrodes

연필 흑연 전극으로 구성된 저비용 바이오 센서를 사용한 SARS-CoV-2의 미세 검출

410

Published on 2021-07-272022-09-10
Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 변종, 진단, 치료기술,

[키워드] Accuracy ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin B.1.1.7 comparable composed condition contagious coronavirus COVID-19 COVID-19 testing cross-reactivity death detect Device diagnosed diagnostic diagnostic test diagnostic tests facilitate graphite help High human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 Influenza lead limit of detection opens Outbreaks phosphate phosphate-buffered saline point of care Prevent reproducibility Saliva SARS-CoV-2 SARS-CoV-2 B.1.1.7 SARS-CoV-2 spike protein sensitivity sensor severe acute respiratory syndrome Coronavirus Significance specificity Spike protein spread of COVID-19 Strains tested unit variant viral spike protein virus viruses
[DOI] 10.1073/pnas.2106724118 PMC 바로가기 [Article Type] 410

Screening Antibodies Raised against the Spike Glycoprotein of SARS-CoV-2 to Support the Development of Rapid Antigen Assays

Article

Published on 2021-07-272022-10-27
Journal: ACS Omega [Category] COVID-19,

[키워드] antibody Antigen antigens Asymptomatic case Biomarker coronavirus Coronavirus-2 country cross-reactivity detection development diagnose Diagnosis diagnostic diagnostic test diagnostic tests diagnostic value disease early stage envelope protein group identify immunoassay immunoassays include infected case Infection lateral flow leading management membrane protein molecular monoclonal antibody nucleocapsid protein promote provided Rapid Rapid diagnostic test Research resources SARS-CoV-2 SARS-CoV-2 spike protein Screening sensitivity serologic serologic tests spike glycoprotein Spike protein Support Surveillance the Spike therapeutic Transmission viral pathogen
[DOI] 10.1021/acsomega.1c01321 PMC 바로가기 [Article Type] Article

Patients with suspected allergic reactions to COVID‐19 vaccines can be safely revaccinated after diagnostic work‐up

Research

Published on 2021-07-272022-10-31
Journal: Clinical and Translational Allergy [Category] COVID-19,

The C-Terminal Half of SARS-CoV-2 Nucleocapsid Protein, Industrially Produced in Plants, Is Valid as Antigen in COVID-19 Serological Tests

Plant Science

Published on 2021-07-272022-10-31
Journal: Frontiers in Plant Science [Category] COVID-19,

[키워드] Affect antibody Antigen biofactories calculated city coronavirus disease Council COVID-19 COVID-19 diagnosis develop Diagnosis diagnostic diagnostic test diagnostic tests ELISA ELISA coronavirus enzyme-linked immunosorbent expressed expression human sera individual Laboratory molecular farming N antigen N protein Nicotiana benthamiana pandemic plant plant expression plants platform positive result producing protein antigen purification reagent Recombinant protein Research Result RT-PCR SARS CoV-2 nucleocapsid protein SARS-CoV-2 SARS-CoV-2 antibody sensitivity Sensitivity and specificity sera serological shown specificity subset Support Test tested the N protein turnaround times was used were used
[DOI] 10.3389/fpls.2021.699665 PMC 바로가기 [Article Type] Plant Science

Structural Basis for SARS-CoV-2 Nucleocapsid Protein Recognition by Single-Domain Antibodies

Immunology

Published on 2021-07-262022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,