Efficient and Sustainable Platform for Preparation of a High-Quality Immunoglobulin G as an Urgent Treatment Option During Emerging Virus Outbreaks신종 바이러스 발생 시 긴급 치료 옵션으로 고품질 면역글로불린 G를 준비하기 위한 효율적이고 지속 가능한 플랫폼Article Published on 2022-05-172022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Affect affected analyzed anti-SARS-CoV-2 approach average caprylic acid caprylic acid precipitation Concentration convalescent plasma convalescent plasma processing correlated COVID-19 COVID-19 pandemic demonstrated donors downstream Effectiveness Efficacy efficient Epidemic Final fraction IgA IgG IgG subclass IgM immunization Immunoglobulin Immunoglobulin G Infectious disease ion-exchange chromatography mass spectrometry Neutralization assay neutralization potency neutralize Neutralizing antibodies offer option outbreak overcome pandemic status Passive immunotherapy plasma polyclonal polyclonal anti-COVID-19 IgG preparation proportion provided purification Quality control reducing reduction remained significantly therapeutic transfusion reactions Treatment viral outbreak wild-type SARS-CoV-2 wild-type SARS-CoV-2 neutralization assay. [DOI] 10.3389/fimmu.2022.889736 PMC 바로가기 [Article Type] Article
Efficient disinfection of SARS-CoV-2-like coronavirus, pseudotyped SARS-CoV-2 and other coronaviruses using cold plasma induces spike protein damage저온 혈장을 사용한 SARS-CoV-2 유사 코로나바이러스, 유사형 SARS-CoV-2 및 기타 코로나바이러스의 효율적인 소독으로 스파이크 단백질 손상 유도Article Published on 2022-05-152022-09-11 Journal: Journal of hazardous materials [Category] COVID19(2023년), SARS, 변종, [키워드] angiotensin atmospheric binding Cold Cold pressure plasma coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 dominant efficient Epidemic Evidence evidence of hACE2 human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 inactivation induce other coronavirus other coronaviruses PEDV Peroxynitrite anion plasma provide pseudotyped SARS-CoV-2 Pseudotyped variants public health emergency pulse raised RBD reactive Receptor binding domain Recognition responsible SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 spike protein receptor binding domain SARS-CoV-2 variant SARS-CoV-2 variants short-lived Short-lived reactive species. Spike protein strain transmission of SARS-CoV-2 variant Viral transmission [DOI] 10.1016/j.jhazmat.2022.128414 PMC 바로가기 [Article Type] Article
An excitation wavelength-optimized, stable SERS biosensing nanoplatform for analyzing adenoviral and AstraZeneca COVID-19 vaccination efficacy status using tear samples of vaccinated individuals백신 접종자의 눈물 샘플을 사용하여 아데노바이러스 및 AstraZeneca COVID-19 예방 접종 효능 상태를 분석하기 위한 여기 파장 최적화된 안정적인 SERS 바이오 센싱 나노 플랫폼Article Published on 2022-05-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] Adenovirus antibody AstraZeneca AZD1222 ChAdOx1 COVID-19 vaccination Efficacy Epidemic Epidemic keratoconjunctivitis fluids Hypothesis identify Immunoglobulin Immunoglobulin G Keratoconjunctivitis lAbel Label-free SERS biosensing platform limit of detection marker Near- and far-field properties Non-invasive Oxford-AstraZeneca Oxford-AstraZeneca vaccine Patient platform product receive reproducibility robust robustness scattering stability Stability and robustness Standard deviation Tear Tear fluids. tears the vaccine vaccinated individual vaccinated individuals vaccination Vaccination Status Vaccine [DOI] 10.1016/j.bios.2022.114079 PMC 바로가기 [Article Type] Article
Analyzing inherent biases in SARS-CoV-2 PCR and serological epidemiologic metricsSARS-CoV-2 PCR 및 혈청학적 역학적 지표에 내재된 편향 분석Observational Study Published on 2022-05-132022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody detection basic reproduction number bias caution Chain Reaction clearance conducted coronavirus Course cross-sectional survey Cross-sectional surveys detectable develop diagnose Effect Epidemic epidemic peak Epidemics epidemiological estimation incidence Infection Inference inherent biase investigated mathematical mathematical model Measures Metrics MONITOR Observational data outcome PCR PCR positivity PCR testing polymerase chain polymerase chain reaction populations positive predicted Prevalence progression Prospective respiratory SARS-CoV-2 SARS-CoV-2 PCR serological Serological testing Seroprevalence severe acute respiratory syndrome Coronavirus tested [DOI] 10.1186/s12879-022-07425-z PMC 바로가기 [Article Type] Observational Study
From crisis to crisis: impacts of the COVID-19 pandemic on people living with HIV and HIV/AIDS service organizations in Indiana위기에서 위기까지: COVID-19 대유행이 인디애나주의 HIV 및 HIV/AIDS 서비스 기관에 거주하는 사람들에게 미치는 영향Article Published on 2022-05-092022-09-11 Journal: BMC health services research [Category] COVID19(2023년), SARS, 치료기술, [키워드] affected AIDS AIDS service organizations Care conducted COVID-19 COVID-19 crisis COVID-19 pandemic Epidemic examined Health HIV HIV/AIDS Impact IMPROVE organization organizations pandemic PLWH Population provided service Socio-ecological model. with HIV [DOI] 10.1186/s12913-022-07998-0 PMC 바로가기 [Article Type] Article
Depressive risk among Italian socioeconomically disadvantaged children and adolescents during COVID-19 pandemic: a cross-sectional online surveyCOVID-19 전염병 동안 이탈리아 사회경제적으로 불리한 아동 및 청소년의 우울 위험: 횡단면 온라인 설문조사Article Published on 2022-05-072022-09-11 Journal: Italian Journal of Pediatrics [Category] COVID19(2023년), SARS, 치료기술, [키워드] activities activity adolescents association children Clinical data conditions COVID-19 COVID-19 outbreak COVID-19 pandemic cross-sectional cross-sectional study Depression depressive depressive symptom Depressive symptoms detect Diagnosis disorders distress Effect effective emotional Emotional response Epidemic expected Factor Families family First wave form implication individual information inventory Italian lack Logistic regression analysis Low-income Mental mental health Neuropsychiatric outbreak pandemic parent participant performed potential risk problem promotion recruited risk socio-demographic Socioeconomic disadvantage. Stressor stressors subject suffered Support therapeutic strategy Version [DOI] 10.1186/s13052-022-01266-x PMC 바로가기 [Article Type] Article
A Robust Framework for Epidemic Analysis, Prediction and Detection of COVID-19COVID-19의 전염병 분석, 예측 및 탐지를 위한 강력한 프레임워크Article Published on 2022-05-062022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Affect Analysis center central limit theorem Chain Reaction circulation composed Coronavirus - COVID-19 country COVID COVID case COVID cases COVID-19 COVID-19 disease COVID-19 infection dataset detect detection disease disease control distribution doubling dry cough Epidemic epidemic spreading algorithm estimate estimation Evolution extreme False-positive feature Features feeble Fever flu Frame framework gaussian gaussian distribution generate Gradient histogram immune systems India individual Infection infections Infectious disease Italy Johns Hopkin Johns Hopkins limit lung mandatory mathematical mathematical model outcome pandemic parameter parameters polymerase chain polymerase chain reaction predict prediction Prevent real-time polymerase chain reaction regulated robust RT-PCR Saudi Arabia scale Spread statistical Symptom the disease thickness time evolution Time-series (TS) model Viral pneumonia widespread [DOI] 10.3389/fpubh.2022.805086 PMC 바로가기 [Article Type] Article
Design of a Recombinant Multivalent Epitope Vaccine Based on SARS-CoV-2 and Its Variants in Immunoinformatics Approaches면역정보학 접근법에서 SARS-CoV-2 및 그 변이체에 기반한 재조합 다가 에피토프 백신의 설계Article Published on 2022-05-062022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] allergen antigen epitope antigen epitopes approach B-cell epitope caused cellular conformational Coverage COVID-19 cytotoxic T lymphocyte docking effective Epidemic epitope Epitopes global public health Humoral immunity Immune simulation immunoinformatics IMPROVE in vitro in vivo Interaction linear B-cell epitope linear B-cell epitopes linker lymphocyte multivalent multivalent vaccine mutated virus Protein recombinant SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants screened strain strong interaction T lymphocyte the vaccine tlr-3 Vaccine variant variants VoC [DOI] 10.3389/fimmu.2022.884433 PMC 바로가기 [Article Type] Article
Introduction and transmission of SARS-CoV-2 lineage B.1.1.7, Alpha variant, in Denmark덴마크에서 SARS-CoV-2 계통 B.1.1.7, 알파 변종 도입 및 전파Article Published on 2022-05-042022-09-11 Journal: Genome Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Alpha variant analyzed applied B.1.1.7 benefit calculated collected contributed COVID-19 Denmark dominant effort Epidemic estimate Genome highlight Including initial Lineage Lineage B.1.1.7 lineages onward transmission Phylogenetic analysis Phylogeny Poisson regression positive representing SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 lineage Self-isolation Sequencing study period Surveillance the SARS-CoV-2 These data Transmissibility transmission of SARS-CoV-2 Travel variants [DOI] 10.1186/s13073-022-01045-7 PMC 바로가기 [Article Type] Article
Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-Viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus유행성, 전염병, 풍토병: B 세포 레퍼토리 분석을 통해 SARS-CoV-2, 에볼라 및 호흡기 세포융합 바이러스에 대한 독특한 항바이러스 반응이 밝혀졌습니다Article Published on 2022-05-032022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] age Analysis B cell Characteristics class-switch recombination (CSR) cohorts COVID-19 COVID-19 patient disease Ebola Ebolavirus Effects Endemic Epidemic event Evidence example Fever germinal centre heterogeneity humoral humoral immune response Hypothesis IgG1 IGH IGHV4-39 immature Immunity infections lack Lineage morbidity and mortality Mutation pandemic patients Recombination reflect repertoire respiratory response risk RSV RSV (respiratory syncytial virus) SARS-CoV-2 Sequencing significant difference Support survivor switching unique vaccination Vaccine viral challenge viral infection Zaire [DOI] 10.3389/fimmu.2022.807104 PMC 바로가기 [Article Type] Article