Genomic surveillance

[키워드] (coronavirus disease 2019 Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amplicon amplicon method Amplicon sequencing analyses Analysis applied approach approaches best capture capture method caused Characteristics clinical sample clinical samples Complete coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cultured isolate demonstrated diagnostics Dilution Efficiency eight Emerging infectious diseases Epidemic Epidemiology Evolution examined Factor full-length SARS-CoV-2 genetic information Genome Genome sequencing genomes Genomic surveillance Guidance Hybrid capture inter- and intra-individual variations inter-individual inter-individual and intra-individual variations intra-host dynamics intra-individual variation iSNV knowledge Metatranscriptomic sequencing Multiple Multiplex PCR novel multiplex PCR amplicon offer PCR amplicon Quasispecies reported respiratory Result SARS-CoV-2 SARS-CoV-2 genome scarcity sensitivity Sequencing severe acute respiratory syndrome Coronavirus Therapeutics ultra-high-throughput metatranscriptomic variations Viral Viral load viral loads viral read Viral transmission virus Virus evolution Virus-host interaction Virus-host interactions viruses whole-genome sequencing
[DOI] 10.1186/s13073-020-00751-4 PMC 바로가기 [Article Type] Research