Messenger RNA – Page 23 – Communicable Diseases Research

From RNA World to SARS-CoV-2: The Edited Story of RNA Viral Evolution

Review

Published on 2021-06-202022-10-31
Journal: Cells [Category] COVID-19, MERS, SARS,

microRNA Heterogeneity, Innate-Immune Defense and the Efficacy of SARS-CoV-2 Infection—A Commentary

Commentary

Published on 2021-06-182022-10-30
Journal: Non-Coding RNA [Category] COVID-19,

[키워드] Homo sapien (hsa) activity acute respiratory distress acute respiratory syndrome biochemical cause cellular Coronavirus-2 COVID-19 COVID-19 pandemic disease Efficiency explain family Coronaviridae Genetic Genome genus Betacoronavirus host cell host miRNAs human miRNA immunological implication indicate individual individuals Infection Inflammatory Invasion Messenger RNA messenger RNA (mRNA) microRNA microRNA (miRNA) miRNA miRNAs modulation mRNA mRNA abundance Neurological complications neutralization non-coding RNA nucleotide pathological pathophysiological progression recent Replication Research SARS-CoV-2 SARS-COV-2 infection Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) single-stranded Support susceptible systemic disease tissue Variability viral genome viral infection Viral pneumonia Viral RNA
[DOI] 10.3390/ncrna7020037 PMC 바로가기 [Article Type] Commentary

Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women

임산부와 수유부에서 코로나19 mRNA 백신의 면역원성

Article

Published on 2021-06-152022-09-11
Journal: JAMA [Category] MERS, SARS, 변종, 진단,

[키워드] antibody Antibody Response Antibody titers assays B.1.1.7 B.1.351 B.1.351 variant B.1.351 variants binding binding and neutralizing antibodies binding domain Blood BNT162b2 breast milk CD4 CD8 T-cell response CD8 T-cell responses Cellular immune response Cord blood COVID-19 COVID-19 vaccine COVID-19 vaccine trials COVID-19 vaccines cross-reactive antibody enrolled enzyme enzyme-linked immunospot evaluate evaluated excluded exploratory Exploratory analysis Fever Follow-up functional Humoral and cellular immune responses IFN-γ immune responses immunogenic immunogenicity ImmunoSpot increased risk lactating lactating women Messenger RNA Moderna morbidity morbidity and mortality mRNA mRNA vaccine mRNA-1273 Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers nonpregnant outcome Pfizer-BioNTech Phase 3 Population pregnant pregnant women preserved prospective cohort study receipt reduced reported response SARS-CoV-2 B.1.1.7 SARS-COV-2 infection SARS-CoV-2 receptor SARS-CoV-2 USA-WA1/2020 SARS-CoV-2 variant SARS-CoV-2 variants Spike-specific T-cell responses T-cell Response T-cell responses the SARS-CoV-2 transported vaccination Vaccine vaccine dose Viral Viral variants were assessed white women
[DOI] 10.1001/jama.2021.7563 PMC 바로가기 [Article Type] Article

COVID-19 vaccines: Frequently asked questions and updated answers

Review article

Published on 2021-06-012022-10-05
Journal: Infectious diseases now [Category] 비임상,

Potential mechanisms of anaphylaxis to COVID-19 mRNA vaccines

COVID-19 mRNA 백신에 대한 아나필락시스의 잠재적 메커니즘

Review

Published on 2021-06-012022-09-11
Journal: The Journal of Allergy and Clinical Immunology [Category] SARS, 유전자 메커니즘,

[키워드] Activation allergic Allergic reactions allergy anaphylactic anaphylaxis antibody Antigen applicability atopic cell activation clinically complement component Contact coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mRNA vaccine COVID-19 vaccine effector cells Genetic glycol Health crisis hydrophilic hypersensitivity in vitro individual individuals less Lipid nanoparticle Lipid nanoparticles marker mast cell Mast cells mechanism messenger Messenger RNA mRNA mRNA vaccine nucleic acid packaged pandemic Pathogenesis Patient PEGylated liposome Polyethylene glycol polyethylene glycol. Polymer Potential predict Predictive Predictive value predisposition Prospective clinical trial public health crisis reaction reactivity risk severe allergic reactions suffered Vaccine vaccine administration vaccine production
[DOI] 10.1016/j.jaci.2021.04.002 PMC 바로가기 [Article Type] Review

Safety and immunogenicity of a first dose of SARS‐CoV‐2 mRNA vaccine in allogeneic hematopoietic stem‐cells recipients

Short Report

Published on 2021-06-012022-10-31
Journal: Ejhaem [Category] COVID-19,

The current landscape of nucleic acid therapeutics

Reviews

Published on 2021-05-312022-10-05
Journal: Nature nanotechnology [Category] 변종, 유전자 메커니즘,

Evaluation of Seropositivity Following BNT162b2 Messenger RNA Vaccination for SARS-CoV-2 in Patients Undergoing Treatment for Cancer

암 치료를 받는 환자에서 SARS-CoV-2에 대한 BNT162b2 메신저 RNA 백신 접종 후 혈청 양성 평가

Research

Published on 2021-05-282022-09-12
Journal: JAMA Oncology [Category] MERS, SARS, 진단,

[키워드] 95% CI accompanied active treatment age analyses Analysis analyzed anti-S Antibody Response Antibody titer anticancer Beilinson Hospital blood sample Blood samples BNT162b2 BNT162b2 vaccine Cancer center Chemotherapy cohort study comparison Comparisons conducted Control control group COVID-19 COVID-19 disease Davidoff defined develop domain Enrollment evaluate exhibited Factor finding greater healthy control healthy controls high risk higher risk IgG IgG antibodies IgG antibody IgG titer IgG titers immunoassay Immunotherapy Importance intravenous measure median men messenger Messenger RNA multivariable analyses multivariable analysis objective outcome participant Participants Patient Patients with cancer Point Primary outcome prospective cohort study receiving Relevance required Research respond Result RNA SARS-CoV 2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose second messenger secondary Secondary outcomes seropositive Seropositivity serum sample serum samples setting severe COVID-19 disease significantly significantly lower solid tumor solid tumors Study participants Support systemic therapy systemic treatment the patient therapy titers Treatment Tumor tumors vaccination vaccine dose
[DOI] 10.1001/jamaoncol.2021.2155 PMC 바로가기 [Article Type] Research

Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients

고형 장기 이식 수혜자에서 단일 용량의 SARS-CoV-2 메신저 RNA 백신의 면역원성

Article

Published on 2021-05-042022-09-12
Journal: JAMA [Category] 진단,

[키워드] Antibody Response COVID-19 vaccine immunocompromised individuals immunogenicity messenger Messenger RNA mRNA Protein recipient RNA SARS-CoV-2 Solid solid organ transplant the vaccine Transplant
[DOI] 10.1001/jama.2021.4385 PMC 바로가기 [Article Type] Article

A Case of Postural Orthostatic Tachycardia Syndrome Secondary to the Messenger RNA COVID-19 Vaccine

Internal Medicine

Published on 2021-05-042022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] activate acute respiratory syndrome antibody autoimmune basis autoimmune pots Autoimmune reaction autonomic Case report clinically conducted connection coronavirus coronavirus disease COVID 19 COVID-19 COVID-19 vaccine diagnosed Diagnosis diagnostic test disease Dizziness Dysautonomia dysfunction fatigue first dose Headaches help immune system implication include male mechanism messenger Messenger RNA Modification mRNA mRNA vaccine mRNA-based vaccine nervous system Numerous onset of symptom orthostatic pathophysiology Patient Prevalence Research RNA secondary to Side effect Symptom syndrome Tachycardia Trigger triggered unique Vaccine Vaccines viruses
[DOI] 10.7759/cureus.14837 PMC 바로가기 [Article Type] Internal Medicine