Epidemiological and clinical features of COVID-19 patients in Saudi ArabiaObservational Study Published on 2021-04-012022-10-04 Journal: Journal of infection and public health [Category] 임상, [키워드] age Asymptomatic CFR clinical feature conducted COVID-19 COVID-19 case COVID-19 patient COVID-19 patients cross-sectional dead death deaths demographic characteristics Fatality rate females help KSA majority male Ministry of Health multicenter network occurred Older outcome pandemic Patient patients with COVID-19 positive COVID-19 reported representing retrospective risk factor SARS-CoV-2 Saudi Arabia Sex SIGN significantly more Symptom Symptoms was collected [DOI] 10.1016/j.jiph.2021.01.003 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 antibody seroprevalence in the general population and high-risk occupational groups across 18 cities in Iran: a population-based cross-sectional study이란 18개 도시의 일반 인구 및 고위험 직업군에서 SARS-CoV-2 항체 혈청 유병률: 인구 기반 횡단면 연구Article Published on 2021-04-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI Abstract acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted age agency Analysis antibody asked blood sample Blood samples city confirmed COVID-19 case contact with coronavirus COVID-19 COVID-19-related symptoms cross-sectional cross-sectional study demographic characteristics detect drug Drug administration education Electronic health record ELISA kits ELISA test epidemic wave epidemic waves estimate exposure to food General population group Health Health Policies health record health-care high risk high-risk population highest IgM antibodies IgM antibody increases in independent Indicator individual infection rate information Iran material medical history Ministry of Health much higher pandemic participant Participants Population size Prevalence prevalence of COVID-19 Prevent proportion provided public health Qom question Randomly Rapid Rasht recruited Registered reported respiratory SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 ELISA SARS-CoV-2-infected individual SARS-CoV-2-infected individuals SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody SARS-CoV-2-specific IgG selected Sensitivity and specificity Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus Sex social contact specific antibodies study participant Study participants test results translation uninfected Variation Weighting were excluded were infected were used [DOI] 10.1016/S1473-3099(20)30858-6 PMC 바로가기 [Article Type] Article
Clinical Efficacy of Hydroxychloroquine in Patients with COVID-19: Findings from an Observational Comparative Study in Saudi ArabiaArticle Published on 2021-03-312022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] according to protocol Admission Antiviral Baha Care carried clinical clinical effectiveness Comparative comparative observational study control group coronavirus disease COVID-19 dose duration of hospitalization Evidence finding groups HCQ hospital Hospital stay Hydroxychloroquine ICU IMPROVE intensive care mechanical ventilation Ministry of Health Mortality mortality rates no significant difference not reduce overall survival Patient patients hospitalized patients with COVID-19 Primary outcome provide receive regimen Saudi Arabia standard treatment treated Treatment treatment group with COVID-19 [DOI] 10.3390/antibiotics10040365 PMC 바로가기 [Article Type] Article
Hospital load and increased COVID-19 related mortality in IsraelArticle Published on 2021-03-262022-10-04 Journal: Nature Communications [Category] SARS, 치료법, [키워드] caused changes in Characteristics Computational models coronavirus disease 19 COVID-19 COVID-19 patient COVID-19 related mortality defined Epidemiology error Healthcare system hospital Hospitalized in-hospital mortality in-hospital mortality rate independent Ministry of Health moderate morbidity mortality rate Patient Patient care patients with COVID-19 SARS-CoV-2 significantly increased Spread Standard the patient Treatment viral infection [DOI] 10.1038/s41467-021-22214-z PMC 바로가기 [Article Type] Article
Trends in Healthcare Access in Japan during the First Wave of the COVID-19 Pandemic, up to June 2020Observational Study Published on 2021-03-222022-10-04 Journal: International Journal of Environmental Research an [Category] SARS, 임상, [키워드] access average Care COVID-19 decrease demonstrated disease evaluated First wave health monitoring healthcare healthcare access healthcare facility hospital Hospital stay hospitalized patient hospitalized patients hospitals Japan management Ministry of Health New coronavirus Outpatient pandemic Pandemics Patient per day Population Psychiatric Regression model Support trend Wave Welfare [DOI] 10.3390/ijerph18063271 PMC 바로가기 [Article Type] Observational Study
On the analysis of mortality risk factors for hospitalized COVID-19 patients: A data-driven study using the major Brazilian databaseResearch Article Published on 2021-03-182022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] addition Admission Affect age Analysis analyzed assist both sexes Brazil cardiac cardiac disease Clinical symptoms Comorbidities Comorbidity condition cough COVID-19 epidemic COVID-19 patient data-driven database demographic diabete diabetes died disease distress Dyspnoea evidenced Factors Fever Gender high mortality Hospitalization Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient hospitalized patients ICU implementation IMV information intensive care Invasive mechanical ventilation Kidney disease knowledge lethality rate male measure Ministry of Health mortality risk mortality risk factor mortality risk factors MOST most prevalent comorbidities Neurological disease obesity Older age outcome oxygen saturation Patient patients physician pneumopathy poor prognosis predictor Prevalence prevalent provide Registered required Result risk factor shown significantly Symptom the disease [DOI] 10.1371/journal.pone.0248580 PMC 바로가기 [Article Type] Research Article
Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6-8 months after the infection감염 후 6~8개월 후 회복 중인 COVID-19 환자에서 SARS-CoV-2 특이적 B 및 T 세포 반응의 지속성Article Published on 2021-03-122022-09-11 Journal: Med (New York, N.Y.) [Category] MERS, SARS, 변종, 임상, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 adaptive Adaptive immune response adaptive immune responses addition anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG Anti-spike antibody B cell binding domain center collected convalescent convalescent COVID-19 patient coronavirus disease Coronavirus disease 2019 Coronavirus-2 Council Course COVID-19 COVID-19 patients COVID-19 research Critical disease declined development Diagnosis disease severity Donor elevated European Horizon IgG immune immune response immune responses Immunity Immunoglobulin immunoglobulin M immunological Immunological memory Infection information Italian Level Longevity longevity of immune response Medicine medium memory B Mild Ministry of Health monitoring National natural infection Neutralizing Neutralizing activity neutralizing antibody onset of symptom patients plasma Protective protective immunity provide remained Research respiratory SARS-CoV-2 serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 significantly lower subset supported Swedish symptom onset T cell T cell response T cell responses tested the patient union vaccination Vaccination strategies Vaccination strategy variants virus [DOI] 10.1016/j.medj.2021.02.001 PMC 바로가기 [Article Type] Article
Stay-At-Home Orders Are Associated With Emergence of Novel SARS-CoV-2 VariantsInternal Medicine Published on 2021-03-112022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome association Brazil collected coronavirus coronavirus disease correlated correlation COVID-19 database death decrease demographics determine E484K E484K mutation eight emergence Evidence explain genomic variant GISAID index individual initiative Isolation lack Lineage material Ministry of Health mutants mutations new SARS-CoV-2 novel P.1 pandemic pathogenic positive correlation Prevalence public health reductions in Region regions Result SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 variants significantly SII social distancing social isolation Spearman variant variants was measured was obtained while [DOI] 10.7759/cureus.13819 PMC 바로가기 [Article Type] Internal Medicine
Ethnic disparities in COVID-19 mortality in Mexico: A cross-sectional study based on national dataResearch Article Published on 2021-03-102022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] 95% confidence interval adjusted odds ratio Affect affected calculate Care confirmed COVID-19 case confounders country COVID-19 COVID-19 mortality COVID-19 pandemic cross-sectional death determine diagnosed with COVID-19 died group higher risk hospital Hospitalized hospitalized patients include Indigenous people Indigenous peoples lack large sample Ministry of Health Mortality National Odds ratio Patient patients patients with COVID-19 proportion public health Racial Result was used with COVID-19 [DOI] 10.1371/journal.pone.0239168 PMC 바로가기 [Article Type] Research Article
Evaluation of the effect of melatonin in patients with COVID-19-induced pneumonia admitted to the Intensive Care Unit: A structured summary of a study protocol for a randomized controlled trial중환자실에 입원한 COVID-19 유발 폐렴 환자에서 멜라토닌의 효과 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-03-082022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 ABG allergy allocation sequence anticipated Arm ARMS arterial blood arterial blood gas Bandar Abbas Blinding block randomization Blood blood gas Breastfeeding C-reactive protein C-RP clinical clinical symptom Clinical symptoms clinical trial clinical trials company comparator conducted Control control group COVID-19 criteria Definitive definitive diagnosis diagnosis of COVID-19 disease Diseases disorders dissemination dose Effect element feature ferritin gelatin generate history ICU inclusion criteria Inflammation intensive care unit intervention group Iran Laboratory Lactate lactate dehydrogenase LDH lung involvement mechanical ventilation melatonin Ministry of Health mortality rate number objective Open-label open-label trial outcome parallel-group participant Participants Patient patients pharmaceutical Pharmaceutical Company Placebo Pneumonia Pregnancy Primary outcome Primary outcomes protocol random randomization randomize Randomized Randomized controlled trial regimen Registered registration date registration number registry renal RT-PCR Sample size screened secondary outcome Secondary outcomes Serological testing Seven severe pneumonia severely ill patient severely ill patients single-center standard treatment status Study protocol supplementary material therapeutic Trial trial protocol Trial registration twice a day underlying diseases Version web-based system website [DOI] 10.1186/s13063-021-05162-3 PMC 바로가기 [Article Type] Letter