Diagnostic Accuracy of SARS-CoV-2 Antigen Detection Test in Children: A Real-Life StudyPediatrics Published on 2021-07-152022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] 95% CI Adults age Antigen children Cohort contact with contagious COVID-19 cycle threshold detect detection diagnosis of COVID-19 enrolled Fever gold standard groups nasopharyngeal swabs no difference Patient pediatric prevalence of COVID-19 primary care rapid antigen test real-life performance recruited RT-PCR SARS-CoV-2 SARS-CoV-2 RT-PCR test Sensitivity and specificity specificity Symptom symptomatic Test university validation study [DOI] 10.3389/fped.2021.647274 PMC 바로가기 [Article Type] Pediatrics
Self-Collected Gargle Lavage Allows Reliable Detection of SARS-CoV-2 in an Outpatient Setting자가 수집 가글 세척으로 외래 환자 환경에서 SARS-CoV-2를 안정적으로 감지Observation Published on 2021-07-142022-09-10 Journal: Microbiology Spectrum [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Care combating Complete coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 testing current detect detection equipment gargle gargle lavage gold gold standard Health Health care Health care system health care systems idea Infectious disease lavage limit Nasopharyngeal swab nasopharyngeal swabs Outpatient outpatients Patient patient cohort provide Qualitative respiratory RNA extraction RT-PCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 pandemic setting severe acute respiratory syndrome Coronavirus specimen strain Support symptomatic was performed while [DOI] 10.1128/Spectrum.00361-21 PMC 바로가기 [Article Type] Observation
Optimal Insertion Depth for Nasal Mid-Turbinate and Nasopharyngeal SwabsArticle Published on 2021-07-142022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] age Antigen antigen test calculated clinical evidence clinical validation COVID-19 COVID-19 test Denmark Depth determine Evidence false-negative flexible inferior turbinate insertion lack mid-turbinate sample nasal nasal swab nasopharyngeal nasopharyngeal sample Nasopharyngeal swab nasopharyngeal swab specimen nasopharyngeal swabs pandemic participant provide risk SARS-CoV-2 specimen Swab tested upper respiratory virus virus virus diagnostics [DOI] 10.3390/diagnostics11071257 PMC 바로가기 [Article Type] Article
ddPCR increases detection of SARS-CoV-2 RNA in patients with low viral loadsDDPCR은 바이러스 부하가 낮은 환자에서 SARS-COV-2 RNA의 검출을 증가시킵니다.Original Article Published on 2021-07-122022-09-10 Journal: Archives of Virology [Category] SARS, 유전자 메커니즘, 진단, 치료기술, 치료법, 치료제, [키워드] airway Cell coding concerning COVID-19 diagnose Diagnosis digital PCR droplet expressed framework French Helicase hospital in vitro increase Infection investigated Molecular diagnosis MONITOR N gene N or E Nasopharyngeal swab nasopharyngeal swabs pandemic Paris Patient PCR positive proportion qPCR RdRP Region replicative RNA RNA sequence RNA sequences RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA scored sensitivity significantly subgenomic RNA supplementary material targets Undetermined upper airway Viral load [DOI] 10.1007/s00705-021-05149-0 PMC 바로가기 [Article Type] Original Article
Pooled sputum to optimise the efficiency and utility of rapid, point-of-care molecular SARS-CoV-2 testing빠른 시점 분자 SARS-COV-2 테스트의 효율성과 유용성을 최적화하기위한 풀링 된 가래Research Article Published on 2021-07-082022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 진단, 치료기술, [키워드] amplified Asymptomatic Cohort coronavirus COVID-19 determine Efficiency first test identify Increases limit of detection maintain MAR molecular molecular diagnostics Nasopharyngeal swab nasopharyngeal swabs no difference offer Patient PCR PCR testing platform point of care point-of-care positive individual positive individuals potential benefit potential benefits Prevalence Probability replicate Result rising SARS-CoV-2 SARS-CoV-2 PCR testing SARS-CoV-2 testing sensitivity signal sputum Sputum sample sputum samples Standard deviation supplementary material tested utility widespread [DOI] 10.1186/s12879-021-06316-z PMC 바로가기 [Article Type] Research Article
Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis장기간 SARS-CoV-2 RNA 바이러스 배출 및 림프구감소증은 예후가 불량한 암 환자에서 COVID-19의 특징입니다Article Published on 2021-07-062022-09-10 Journal: Cell Death and Differentiation [Category] SARS, 유전자 메커니즘, 임상, 치료기술, [키워드] accompanied activated acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 anti-RBD IgG antibodies association Blood Cancer cancer patient Cancer patients Cancer therapy carriers CD8 cells circulation coronavirus Coronavirus-2 correlated COVID-19 COVID-19 severity cycle threshold death Depletion DNA early phase Elevation Enterobacteriaceae Eomes exacerbate exhibited family members favor follicular granzyme granzyme B Gut hallmark higher risk IFN immature immunopathology Infection Infectious disease lymphocyte Lymphocyte count lymphopenia magnitude malignant disease mechanism Medical research metabolite metabolites Monocytes Nasopharyngeal swab nasopharyngeal swabs Neutrophils pandemic paradoxical pathway Patient PD-1 plasmablasts polyamine poor prognosis Prognostic markers Prolonged RBD IgG reduce respiratory RT-qPCR salt SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection serum severe COVID-19 significant changes in T-helper cells Viral Viral RNA Viral RNA shedding virus virus–host interaction virus–host interactions worsened [DOI] 10.1038/s41418-021-00817-9 PMC 바로가기 [Article Type] Article
Comparison of saliva with healthcare workers- and patient-collected swabs in the diagnosis of COVID-19 in a large cohort대규모 코호트에서 Covid-19의 진단에서 의료 근로자 및 환자 수집 면봉과의 타액 비교Comparative Study Published on 2021-07-052022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 진단, 치료기술, [키워드] addition Asymptomatic asymptomatic patients calculated collected Community comparator conducted detect determine diagnosis of COVID-19 early stage enrolled Evidence HCW HCWs healthcare healthcare worker Healthcare workers highest hospital hospitalized patient hospitalized patients IMPROVE Inpatients large cohort MedCalc Nasopharyngeal swab nasopharyngeal swabs Negative predictive value NPs NPV offered onset of symptom onset of symptoms optimization Outpatient outpatients Patient positive PPV Predictive Predictive value predictive values qRT-PCR recruited Result Saliva sampling SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2-positive patient Self-swab sensitivity specificity Swab swabs Symptom symptomatic symptomatic patient Symptomatic patients tested was performed [DOI] 10.1186/s12879-021-06343-w PMC 바로가기 [Article Type] Comparative Study
Evaluation of a Rapid Antigen Test To Detect SARS-CoV-2 Infection and Identify Potentially Infectious IndividualsSARS-CoV-2 감염을 감지하고 감염 가능성이 있는 개인을 식별하기 위한 신속한 항원 검사 평가Virology Published on 2021-07-022022-09-10 Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 치료기술, [키워드] addition adjusted antigen detection antigen test collected COVID-19 Culture detected patient diagnostic evaluate feasibility individual individuals infected individuals infectiousness inoculated Isolation lack Nasopharyngeal swab nasopharyngeal swabs positive rate positive result public health Rapid reached representing resulting RNA load RNA loads RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected individual Screening sensitivities sensitivity Sensitivity and specificity Standard Q Test tested Vero E6 VERO E6 cells Viral virus virus culture virus cultures were used [DOI] 10.1128/JCM.00896-21 PMC 바로가기 [Article Type] Virology
Mass Spectrometric Analysis of Urine from COVID-19 Patients for Detection of SARS-CoV-2 Viral Antigen and to Study Host ResponseSARS-CoV-2 바이러스 항원 검출 및 숙주 반응 연구를 위한 COVID-19 환자의 소변 질량 분광 분석Article Published on 2021-07-022022-09-11 Journal: Journal of Proteome Research [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute phase response Affect alteration Amino acid amino acid transporter Analysis approach body fluid body fluids Brain capture Chain Reaction complement complement system coronavirus COVID-19 COVID-19 negative COVID-19 patient COVID-19 patients Culture detect detection diagnosed Glucose immune response in urine Infection involved Kidney function kidneys liver Lungs mass mass spectrometry microbial Nasopharyngeal swab nasopharyngeal swabs NPHS2 nucleocapsid protein organ Pathogenesis pathogenesis of COVID-19 peptide peptides polymerase chain polymerase chain reaction positive Protein proteome proteomic proteomics public health Quantitative quantitative proteomic analysis Regulation renal response reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV-2 positive individual SARS-CoV-2 positive individuals SLC36A2 SLC5A10 sodium subset transcriptase Urine Viral Viral antigen viral antigens Viral RNA virus were used [DOI] 10.1021/acs.jproteome.1c00391 PMC 바로가기 [Article Type] Article
Salivary glands are a target for SARS-CoV-2: a source for saliva contamination침샘은 SARS-CoV-2의 표적입니다: 타액 오염의 원인Article Published on 2021-07-012022-09-11 Journal: The Journal of pathology [Category] SARS, 치료기술, 치료법, 치료제, [키워드] ACE2 acinar cell age alteration Analysis analyzed anti-SARS-CoV-2 antibody Autopsy biopsy Cell cells change characterized Cluster conducted Contamination Coronaviridae family COVID-19 COVID-19 pandemic cytoplasm cytoplasmic degeneration degenerative determinant determinants Diagnostic method duct electron microscopy enlarged nuclei epithelial cell epithelial cells expression female Granule Great Britain highlight histopathological identify immunohistochemistry infected cell infected cells Infection infection control Ireland lining epithelium male Microscopy nasopharyngeal swabs New coronavirus new coronavirus SARS-CoV-2 nuclear nuclear pleomorphism nucleocapsids organelle pathological pathophysiological Patient patients positive profile Qualitative Quantitative receptors reservoir RT-PCR RT-PCR, SARS-CoV-2 RT-qPCR Saliva salivary salivary gland salivary gland. salivary glands Sample SARS-CoV-2 sensitivity shape Society Sons Spread tested the Coronaviridae the disease TMPRSS Ultrasound vacuolization Viral particles viral replication [DOI] 10.1002/path.5679 PMC 바로가기 [Article Type] Article