Social deprivation as a risk factor for COVID-19 mortality among women and men in the UK Biobank: nature of risk and context suggests that social interventions are essential to mitigate the effects of future pandemicsOriginal Research Published on 2021-11-272022-10-29 Journal: Journal of epidemiology and community health [Category] Coronavirus, MERS, SARS, [키워드] 95% CI Adjustment age alleviate association associations baseline cardiovascular disease cause continuous scale COVD-19 COVID-19 COVID-19 mortality death Deprivation died Effect Effects Evidence Factor fatal influenza greater incidence Infection Intervention lack magnitude men mitigate Mortality National objective other diseases outcome measure Pandemics participant person years Pneumonia Prospective quantified Result resulting risk risk factor score setting Sex difference social class social deprivation UK biobank women [DOI] 10.1136/jech-2020-215810 PMC 바로가기 [Article Type] Original Research
Heart Failure Probability and Early Outcomes of Critically Ill Patients With COVID-19: A Prospective, Multicenter StudyCardiovascular Medicine Published on 2021-11-262022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] 95% CI age albumin all-cause mortality analyzed applied assist bootstrap C-index cardiac function clinical suspicion coronavirus disease COVID-19 Critically ill patient enrolled failure Follow-up heart heart failure highlighting Ill IMPROVE In-hospital death laboratory-confirmed lymphocyte Mortality mortality rate multicenter multicenter study multivariate logistic regression nomogram NT-proBNP operator outcome Patient patients died predict Predictive predominant Primary outcome Probability Prognosis Prospective Prospective Study risk factor risk stratification screened significantly higher the patient total bilirubin unlikely with COVID-19 zone [DOI] 10.3389/fcvm.2021.738814 PMC 바로가기 [Article Type] Cardiovascular Medicine
Waning of Anti-spike Antibodies in AZD1222 (ChAdOx1) Vaccinated Healthcare Providers: A Prospective Longitudinal StudyPreventive Medicine Published on 2021-11-252022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Administered affecting age Analysis antibody antibody kinetics Antibody titer AstraZeneca vaccine average AZD1222 binding antibody unit blood sample BMI booster dose Breakthrough infection breakthrough infections ChAdOx1 chadox1 ncov19 vaccine ChAdOx1 vaccine chemiluminescence collected conducted coronavirus Coronavirus disease 2019 COVID vaccine COVID-19 COVID-19 vaccine Covishield dose doses Factor Factors first dose geometric globe healthcare facility Healthcare professional history IgG IgG titer immunoassay Immunoglobulin intramuscularly Kinetics linear mixed model longitudinal material Medical Science men Microparticle mixed model Nurses obese occurred Older overweight pandemic participant Person potential benefit Prospective Research Result SARS-CoV-2 SARS-COV-2 infection second dose seroreversion Seven shown tested the receptor-binding domain the spike protein the vaccine titer vaccination Vaccine vaccine dose viral particle women [DOI] 10.7759/cureus.19879 PMC 바로가기 [Article Type] Preventive Medicine
Nationwide Deployment of a Serious Game Designed to Improve COVID-19 Infection Prevention Practices in Switzerland: Prospective Web-Based StudyOriginal Paper Published on 2021-11-252022-10-30 Journal: JMIR Serious Games [Category] COVID-19, [키워드] 95% CI affected age asked automated Behavior boredom checklist Complete conducted counterproductive Course COVID-19 COVID-19 infection COVID-19 pandemic creating Deployment dissemination effective element ENhance escape Evolution facilitate Factor game gaming health information heterogeneous identify inefficient Infection prevention Intention Internet lack less measure National objective Odds ratio Older Other outcome participant Personal protective equipment platform populations potential participant Practice prevention Primary outcome proportion Prospective public health questionnaire Region reported Reporting Result SARS-CoV-2 secondary secondary outcome serious game survey Switzerland Web-based web-based study [DOI] 10.2196/33003 PMC 바로가기 [Article Type] Original Paper
Low Incidence of COVID-19 Infection in Patients with Acute Myeloid Leukemia Undergoing Reduced Intensity/Venetoclax Based Treatment: Initial Results of the PACE Prospective Clinical Study from the UK Trials Acceleration ProgramConference abstract Published on 2021-11-232022-10-05 Journal: Blood [Category] 유전자 메커니즘, 임상, 치료법, [키워드] acceleration AML Analysis Asymptomatic BMS board Celgene Chemotherapy clinical clinical study clinical trial Cohort cohort of patient concerning conducted Coronavirus disease 2019 cough COVID-19 COVID-19 infection cure death defined determine Diagnosis disease download education employment estimate exacerbated Exploratory analysis Fever figure Follow-up funding Hematological malignancy higher risk hospital immune response Immunosuppression incidence incidence of COVID-19 increasingly indicate Infection information intensity Intensive Jazz MDs median age myelodysplasia myeloid Non-COVID-19 Occurrence outcome pandemic Patient patient hospitalization patients patients treated Patients with cancer PCR test positive presenting symptom Program proportion Prospective provide receiving recruited reduce regimen regimens required Result resulting risk of COVID-19 risk of death SARS-CoV2 secondary severity speaker suffered Support table Takeda tested treated patients Treatment treatment arm treatment history vaccination venetoclax were infected [DOI] 10.1182/blood-2021-146061 [Article Type] Conference abstract
Efficacy and Safety of Lianhuaqingwen Capsules for the Prevention of Coronavirus Disease 2019: A Prospective Open-Label Controlled TrialResearch Article Published on 2021-11-232022-10-31 Journal: Evidence-based Complementary and Alternative Medicine : eCAM [Category] COVID-19, [키워드] Capsule Chinese close contact conducted control group Controlled Controlled trial Coronavirus disease 2019 COVID-19 COVID-19 pandemic determine effective Effectiveness Efficacy global pandemic infected with COVID-19 Influenza LianhuaQingwen nasal no significant difference nucleic acid test observation observation period Open-label patients Pharyngeal swab positive Prevent prevention prevention of COVID-19 primary endpoint profiles progression Prospective quarantine Registered reported Safety Serious Adverse Event significantly lower subject Treatment treatment group Trial [DOI] 10.1155/2021/7962630 PMC 바로가기 [Article Type] Research Article
Inherited Thrombophilias Are Associated with an Increased Risk of COVID-19 Associated Venous Thromboembolism: A Prospective Population-Based Cohort StudyConference abstract Published on 2021-11-232022-10-05 Journal: Blood [Category] 변종, [키워드] 95% CI addition age Analysis antithrombotic therapy assist association characterising chromosome classification Clinical characteristics COVID-19 COVID-19 diagnosis COVID-19 mortality COVID-19 patient death defined demographic determine diagnosed with COVID-19 died download European evaluate evaluated factor V female figure Future genome-wide analysis Genome-wide association study higher risk ICD-10 Increased individual Leiden modify Mutation occurrence of COVID-19 participant patient cohort population-based cohort positive individual Prospective Prospective Study prothrombin recruitment required revision risk risk of COVID-19 risk score shown Single nucleotide polymorphism SNP SNPs synonymous table the median Thrombophilia thrombotic event UK biobank variant Venous Thromboembolism VTE was performed with COVID-19 [DOI] 10.1182/blood-2021-149841 [Article Type] Conference abstract
Prospective Assessment of Biomarkers of Hypercoagulability in Oncological Patients and Healthcare Workers Following Vaccination Against Sars-Cov-2 with the mRNA Vaccine. the Roadmap-COVID-19-Vaccin StudyConference abstract Published on 2021-11-232022-10-05 Journal: Blood [Category] 바이오마커, [키워드] Activation active cancer administration Against antibody assessment Biomarker Blood blood sample BNT162b2 BNT162b2 vaccine calculated centrifugation collected conducted Control control group controls COVID-19 COVID-19 vaccine E-selectin Effect endothelial Endothelial cell Endothelium Evidence expected Factor first dose France funding FVIII groups Health Health care worker Hospital admission Host hypercoagulability immune response individual inflammatory reaction inhibitor Injury less limit Mild MRI mRNA mRNA vaccines no difference not significantly different of BNT162b2 pathway Patient Patients with cancer peak PF4 Pfizer/BioNTech plasma Platelet platelet activation Prevent Probably procoagulant Prospective prospective observational study provoke raised reported resulting risk Sample severe disease shown significantly higher significantly increased stratified subject Support symptomatic infection temperature TFPI the spike protein thrombin thrombosis thrombotic complication thrombotic event tissue triggered UNL vaccinated individual vaccinated individuals vaccination Vaccine Vaccines Venous thrombosis virus von Willebrand factor were assessed worker [DOI] 10.1182/blood-2021-146803 [Article Type] Conference abstract
12-month SARS-CoV-2 antibody persistency in a Tyrolean COVID-19 cohortTyrolean COVID-19 코호트에서 12개월 SARS-CoV-2 항체 지속성Original Article Published on 2021-11-232022-09-10 Journal: Wiener Klinische Wochenschrift [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus age Anti-viral antibody antibody concentration Antibody Response antibody response against Arthritis B.1.1.7 B.1.351 B.1.351 variant binding antibody Concentration concentrations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 cohort cut-off cut-off point declining disease disease onset ELISA except for Follow-up healthy Immunity less Neutralizing Neutralizing antibodies neutralizing antibody nucleocapsid protein Prospective RBD Receptor binding domain respiratory Result rheumatoid arthritis SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV‑2 severe acute respiratory syndrome Coronavirus shown Spike protein supplementary material the RBD the spike protein titre vaccinated against COVID-19 vaccination variants virus were used wild type [DOI] 10.1007/s00508-021-01985-x PMC 바로가기 [Article Type] Original Article
Effects of SARS-CoV-2 Infection During Late Pregnancy on Early Childhood Development: A Prospective Cohort StudyPediatrics Published on 2021-11-232022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] acute respiratory syndrome affected approved association Breastfeeding childhood children China Chinese Cohort conducted coronavirus coronavirus disease COVID-19 demographic characteristics developmental delay early childhood development Effect enrolled ethics committee Evidence indirect effect Infants Infection infection cohort Linear regression model mediation model medical record Mother-infant separation multivariable Observational cohort study offspring participant Poisson regression model Pregnancy Preterm birth Prospective risk SARS-CoV-2 SARS-COV-2 infection SASRS-COV-2 Science Stage university were used [DOI] 10.3389/fped.2021.750012 PMC 바로가기 [Article Type] Pediatrics