SARS-CoV-2 RNA in Swabbed Samples from Latrines and Flushing Toilets: A Case-Control Study in a Rural Latin American Setting변소 및 수세식 화장실의 면봉 샘플에서 SARS-CoV-2 RNA: 농촌 라틴 아메리카 환경에서의 사례 대조 연구Article Published on 2021-01-132022-09-11 Journal: The American Journal of Tropical Medicine and Hygi [Category] 치료기술, [키워드] 95% CI addition adjusted association can not case-control study Contamination contribute covariate Factor fecal Fecal contamination FIVE Flushing Latin latrine likelihood logistic regression model pandemic Randomly Real-time PCR reduce reservoir reservoirs Sample SARS-CoV-2 SARS-CoV-2 RNA selected seropositive subjects setting Spread Struck by subject Swab swabs toilets Viral Viral transmission [DOI] 10.4269/ajtmh.20-1380 PMC 바로가기 [Article Type] Article
Increased sensitivity using real-time dPCR for detection of SARS-CoV-2Comparative Study Published on 2021-01-012023-07-11 Journal: BioTechniques [Category] SARS, [키워드] dPCR Gene Expression infectious disease diagnostics qPCR real-time digital PCR. Real-time PCR SARS-CoV-2 [DOI] 10.2144/btn-2020-0133 PMC 바로가기 [Article Type] Comparative Study
Fatal outcome of anti-MDA5 juvenile dermatomyositis in a paediatric COVID-19 patient: a case report소아 코로나19 환자에서 발생한 항MDA5 소아 피부근염의 치명적 결과: 증례 보고Case Reports Published on 2021-01-012022-09-11 Journal: Modern rheumatology case reports [Category] 진단, 치료제, [키워드] addition Admission Anti-MDA5 BAL BAS Bronchoalveolar lavage Case report children COVID-19 Cyclophosphamide dermatomyositis diagnosed died disease drug emphysema health condition hemophagocytic lymphohistiocytosis high mortality rate high risk hospital hypoxemic Hypoxemic respiratory failure Immunoglobulin immunosuppressive immunosuppressive therapy Infection initiated Intensive Interstitial lung disease interstitial lung disease (ILD) intravenous Intravenous immunoglobulin juvenile dermatomyositis Lung disease MDA5 Methylprednisolone outcome Patient performed Pneumomediastinum Pneumothorax poor prognosis positive Real-time PCR real-time RT-PCR referred to Respiratory failure risk risk for disease SARS-CoV-2 SARS-COV-2 infection secondary hemophagocytic lymphohistiocytosis Septic shock severe complications subcutaneous emphysema sulfamethoxazole therapy Tofacitinib Treatment worsening [DOI] 10.1080/24725625.2020.1832755 PMC 바로가기 [Article Type] Case Reports
SARS-CoV-2 Infection and the COVID-19 Pandemic Emergency: The Importance of Diagnostic MethodsReview Published on 2021-01-012023-06-19 Journal: Chemotherapy [Category] MERS, [키워드] antigen test Coronavirus disease 2019 pandemic Real-time PCR serology severe acute respiratory syndrome coronavirus 2 [DOI] 10.1159/000515343 PMC 바로가기 [Article Type] Review
Visual Detection of SARS-CoV-2 RNA by Conventional PCR-Induced Generation of DNAzyme SensorMolecular Biosciences Published on 2020-12-232022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] catalytic Colorimetric assay comparable Conventional correlation COVID-19 COVID-19 cases COVID-19 transmission Ct-value curtail detection develop diagnose diagnosis of SARS-CoV-2 diagnostic DNAZyme Generation gold standard imperative labor-intensive molecular Nasopharyngeal swab PCR polymerase chain Real-time PCR real-time-PCR RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Sensitivity and specificity sensor shown Spearman specimen unmet need Visual [DOI] 10.3389/fmolb.2020.586254 PMC 바로가기 [Article Type] Molecular Biosciences
Manufacturing of convalescent plasma of COVID-19 patients: Aspects of quality코로나19 환자의 회복기 혈장 제조: 품질 측면Research Article Published on 2020-12-222022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] antibody Antibody titer Antibody titers aspect binding antibodies binding antibody Blood confirmation convalescent plasma coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients domain Donor donors ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay feasible Final followed by IgG IL-8 LBP Level median Negative PCR pandemic patient safety PCR test performed Peripheral blood plasma Plasmapheresis Production RBD Real-time PCR Recovered COVID-19 patients resulting RT-PCR S-protein Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 specific antibodies screened selected severely ill COVID-19 patients subsequent the SARS-CoV-2 titer Treatment undergo [DOI] 10.1371/journal.pone.0243967 PMC 바로가기 [Article Type] Research Article
Evaluation of the diagnostic accuracy of a new point-of-care rapid test for SARS-CoV-2 virus detectionSARS-CoV-2 바이러스 검출을 위한 새로운 현장 진료 신속 검사의 진단 정확도 평가Research Published on 2020-12-212022-09-10 Journal: Journal of Translational Medicine [Category] MERS, SARS, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis analyzed coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Descriptive statistics Diagnosis diagnostic Diagnostic accuracy Emergency use evaluated FDA Finder Health Health surveillance IMPROVE Laboratory less management PCR method point-of-care Point-of-care rapid test provide Rapid test real time real time PCR Real-time PCR reference method required respiratory Result retrospective SAME AS SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 testing SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus significantly shorter Spread Standard of care Surveillance test results were used [DOI] 10.1186/s12967-020-02651-y PMC 바로가기 [Article Type] Research
CoV2-ID, a MIQE-compliant sub-20-min 5-plex RT-PCR assay targeting SARS-CoV-2 for the diagnosis of COVID-19COVID-19 진단을 위한 SARS-CoV-2를 표적으로 하는 MIQE 준수 서브-20분 5-plex RT-PCR 분석인 CoV2-IDArticle Published on 2020-12-172022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 변종, 치료기술, 치료제, [키워드] Biological techniques Biotechnology Complete COVID-19 disease COVID-19 negative COVID-19 positive patient D614G mutation detect develop Diagnosis diagnosis of COVID-19 FIVE fluorescence detection Genotype human cell human cells Internal control limit of detection misunderstanding Molecular biology mutant negative patients patients positive patients qPCR test quantification Real-time PCR reduce reliability RNA RNA sample RNA samples robust RT-PCR assay RT-qPCR test SARS-CoV-2 sensitivity significantly single copy target Target genes tested unique Viral viral infections Viral RNA wild type [DOI] 10.1038/s41598-020-79233-x PMC 바로가기 [Article Type] Article
Analysis of the Fatality Rate in Relation to Testing Capacity during the First 50 days of the COVID-19 Epidemic in Italy이탈리아 코로나19 확산 초기 50일 동안 검사능력 대비 치명률 분석Articles Published on 2020-12-152022-09-10 Journal: The American Journal of Tropical Medicine and Hygi [Category] MERS, SARS, 진단, 치료기술, [키워드] affected analyzed ascertainment bias best calculated Capacity Case fatality rate CFR country COVID-19 COVID-19 epidemic COVID-19 pandemic cumulative death deaths decrease detect Distortion early stage early stages evaluate expected facilitated Fatality rate Final highest initial Insufficient Isolation Italian Italy Logistic logistic curves outbreak PCR tests performed positive positive correlation Positive test predicted Rate Real-time PCR relation study period Surveillance Testing the epidemic Transmission widespread [DOI] 10.4269/ajtmh.20-0862 PMC 바로가기 [Article Type] Articles
Clinical features and outcome of maintenance hemodialysis patients with COVID-19 from a tertiary nephrology care center in RomaniaObservational Study Published on 2020-12-132022-10-04 Journal: Renal failure [Category] SARS, 임상, [키워드] Abnormalities Admission analyzed Anemia anticoagulation atherosclerotic Care cause chest X-ray Chronic hemodialysis clinical Clinical characteristics Clinical course Clinical features Comorbidity Coronary heart disease cough COVID-19 Cox regression analysis death Diabetic discharged distress Dyspnea Factor fatigue feature Fever Hemodialysis high mortality rate Hospitalization Hospitalized Hydroxychloroquine increased mortality information Kidney disease Lopinavir–ritonavir lower oxygen saturation median age men Mortality nephropathy outbreak outcome oxygen saturation Patient patients patients died patients hospitalized patients with COVID-19 poor prognosis Prophylactic Real-time PCR Result retrospective Romania serum albumin severity significantly higher single-center study Symptom syndrome systemic glucocorticoids Tocilizumab Treatment Vascular with COVID-19 [DOI] 10.1080/0886022X.2020.1853571 PMC 바로가기 [Article Type] Observational Study