An Elderly COVID-19 Patient with Community-Acquired Legionella and Mycoplasma Coinfections: A Rare Case ReportCase Report Published on 2021-11-212022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] Legionella pneumophila Mycoplasma pneumoniae acute respiratory syndrome Admission Atypical atypical bacteria Bacterial coinfection Care clinical manifestation Coinfection Combination community-acquired pneumonia COVID-19 Critical Diagnosis discharged home effective elderly Health care system hospital Hospital-acquired infection Hospitalization incidence Infection Legionella Legionella pneumophila management MOST Mycoplasma Mycoplasma pneumoniae occurred Patient report reported respiratory pathogen SARS-CoV-2 SARS-CoV-2 patient Screening serological Treatment [DOI] 10.3390/healthcare9111598 PMC 바로가기 [Article Type] Case Report
Comparison of the Results of Five SARS-CoV-2 Antibody Assays before and after the First and Second ChAdOx1 nCoV-19 Vaccinations among Health Care Workers: a Prospective Multicenter Study의료 종사자의 1차 및 2차 ChAdOx1 nCoV-19 백신 접종 전후 5건의 SARS-CoV-2 항체 분석 결과 비교: 전향적 다기관 연구Multicenter Study Published on 2021-11-182022-09-12 Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 진단, [키워드] Abbott acute respiratory syndrome Adverse reaction antibody Antibody titer applied assay assays AstraZeneca Blood ChAdOx1 nCoV-19 changes in Characteristics contributing to coronavirus Efficacy evaluated first dose first vaccination FIVE Genscript IgG immunoassays multicenter study neutralizing antibody participant positive rate Prospective questionnaire reduced Result Roche SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 pandemic SD Biosensor second second dose second vaccination serological serum sample severity Siemens Symptoms titer vaccination Vaccine Virus neutralization [DOI] 10.1128/JCM.01788-21 PMC 바로가기 [Article Type] Multicenter Study
Evaluating Humoral Immunity against SARS-CoV-2: Validation of a Plaque-Reduction Neutralization Test and a Multilaboratory Comparison of Conventional and Surrogate Neutralization AssaysSARS-CoV-2에 대한 체액 면역 평가: 플라크 감소 중화 테스트 및 기존 및 대리 중화 분석의 다중 실험실 비교 검증Research Article Published on 2021-11-172022-09-12 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, [키워드] addition antibody antibody tests approval assays characterized conducted Conventional COVID-19 COVID-19 vaccines death demonstrated ELISA ENhance enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluate Evaluating flow cytometry Health Organization human ACE2 human ACE2 receptor humoral Humoral immunity immune responses Immunity immunoserology include laboratory-confirmed Laboratory-confirmed COVID-19 lentiviral luciferase multitude natural immunity neutralization neutralization test neutralization tests Neutralizing Neutralizing antibodies Neutralizing antibody response offer outlined Patient plaque-reduction neutralization test platform Precision PRNT Protective protective immune response protective immunity pseudotype quantification reference standard SARS-CoV-2 SARS-CoV-2 PRNT SARS-CoV-2-neutralizing antibodies serological Serological assay specificity specimen surrogate Test Vaccine validation World Health Organization [DOI] 10.1128/Spectrum.00886-21 PMC 바로가기 [Article Type] Research Article
Investigating Adherence to COVID-19 Vaccination and Serum Antibody Concentration among Hospital Workers—The Experience of an Italian Private HospitalBrief Report Published on 2021-11-162022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adherence administration anti-S antibodies anti-S antibody antibody approach conducted contraindication COVID-19 cut-off database effective evaluate experience First wave healthcare worker hospital Hospital staff Infection Italian pandemic Private questionnaire receiving SARS-CoV-2 SARS-CoV-2 transmission second dose serological the vaccine vaccination vaccine adherence Vaccine hesitancy was used [DOI] 10.3390/vaccines9111332 PMC 바로가기 [Article Type] Brief Report
Immunoinformatics mapping of potential epitopes in SARS-CoV-2 structural proteinsResearch Article Published on 2021-11-152022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Algorithm Antibody detection antigenic approved assays coronavirus coronavirus disease COVID-19 COVID-19 vaccine diagnostic effective effective vaccine Efficacy epitope epitope-based vaccines experimental evidence experimental validation facilitate Genetic immune immune response immunological Infection Multi-epitope vaccine N protein non-allergenic patients with COVID-19 platform potential immune epitope predict predicted PROTECT reduce risk Safe SARS-CoV SARS-CoV-2 selected serological structural protein structural proteins Support T cell T-cell epitope target the vaccine Vaccine vaccine candidate variants of SARS-CoV-2 [DOI] 10.1371/journal.pone.0258645 PMC 바로가기 [Article Type] Research Article
Rapid, Cheap, and Effective COVID-19 Diagnostics for AfricaReview Published on 2021-11-132022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] acute respiratory syndrome African amplification Analysis Antibody testing Antigen article Asymptomatic Contact coronavirus country COVID-19 COVID-19 diagnosis COVID-19 diagnostics COVID-19 pandemic diagnose diagnostic diagnostics English Epidemic estimate Evidence feasibility Google Scholar groups highlight include Infection isothermal isothermal amplification knowledge LAMP management mass infection mitigate molecular molecular assays mortality rate nucleic acid amplification polymerase polymerase chain populations Precision public health measure quarantine Rapid Rapid test recombinase amplification RT-PCR SARS-CoV-2 SARS-CoV-2 RT-PCR searched serological shielding transcriptase utility virus [DOI] 10.3390/diagnostics11112105 PMC 바로가기 [Article Type] Review
Antibody status and cumulative incidence of SARS-CoV-2 infection among adults in three regions of France following the first lockdown and associated risk factors: a multicohort study첫 번째 폐쇄 및 관련 위험 요인에 따른 프랑스 3개 지역 성인의 항체 상태 및 SARS-CoV-2 감염 누적 발생률: 다중 코호트 연구Article Published on 2021-11-102022-09-12 Journal: International Journal of Epidemiology [Category] MERS, SARS, 진단, [키워드] adjusted Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody Cohort confidence interval COVID-19 cumulative ELISA estimate First wave France French General population Identifier identify IgG incidence lockdown Multiple participant Participants positive Primary outcome Randomly Region risk risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection selected serological Seropositivity Seroprevalence smoker the spike protein virus was used [DOI] 10.1093/ije/dyab110 PMC 바로가기 [Article Type] Article
High variability in transmission of SARS-CoV-2 within households and implications for controlResearch Article Published on 2021-11-102022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% CI Accuracy acute respiratory syndrome assumption average calculated coronavirus driven by effort Epidemic estimate estimates Evidence Factors False positive growth high risk high variability household transmission implication include individual infected individual infected individuals likelihood Mitigation pandemic Probability required Result SARS-CoV-2 SARS-CoV-2 antibody test SARS-COV-2 infection SARS-CoV-2 test SARS-CoV-2 transmission secondary attack rate Sensitivity and specificity serological serological test serology specificity Spread These data threshold Transmissibility Transmission transmission of SARS-CoV-2 Utah Variability virus [DOI] 10.1371/journal.pone.0259097 PMC 바로가기 [Article Type] Research Article
Differences in IgG Antibody Responses following BNT162b2 and mRNA-1273 SARS-CoV-2 VaccinesResearch Article Published on 2021-11-102022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, [키워드] age and gender antibodies antibody antibody kinetics Antibody Response average binding domain BNT162b2 BNT162b2 vaccine changes in clinically clinician Cohort COVID-19 COVID-19 pandemic defined difference dosage dose regimen elicited first dose Follow-up human cell IgG IgG antibody IgG response immune system immunization immunosuppressive drugs linear Moderna mRNA mRNA platform mRNA vaccine mRNA-1273 mRNA-1273 vaccine overcome participant peaked Pfizer/BioNTech powerful tool Prospective regimens regression modeling remained response S-protein SARS-CoV-2 SARS-CoV-2 vaccine second dose seroconverted serological Serologically seronegative participants significantly higher Spike protein the SARS-CoV-2 the vaccine titer translated vaccination Vaccine Vaccines virus spike protein was used were measured [DOI] 10.1128/Spectrum.01162-21 PMC 바로가기 [Article Type] Research Article
Development of at-home sample collection logistics for large-scale seroprevalence studies대규모 혈청 유병률 연구를 위한 재택 검체 채취 물류 개발Research Article Published on 2021-11-042022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] Blood Blood samples condition COVID19 development effective effort Engagement enrolled Enrollment Massachusetts methodology pandemic participant Participants populations positive positive feedback Racial recruitment reported Result Safe serological serological survey specimens Study design while [DOI] 10.1371/journal.pone.0258516 PMC 바로가기 [Article Type] Research Article