Challenges of drug-resistant malaria약물 내성 말라리아의 도전 과제Review Article Published on 2014-11-182024-08-13 Journal: Parasite [Category] 말라리아, [키워드] drug resistance malaria Nanotechnology peptides RNAi stem cell [DOI] 10.1051/parasite/2014059 PMC 바로가기 [Article Type] Review Article
A Dual Role for SOX10 in the Maintenance of the Postnatal Melanocyte Lineage and the Differentiation of Melanocyte Stem Cell Progenitors출생 후 멜라닌 세포 계통의 유지와 멜라닌 세포 줄기 세포 전구체의 분화에서 SOX10의 이중 역할Research Article Published on 2013-07-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adult stem cells appear Author cause Cell cell fate cell type Critical differentiation downregulated downstream driving embryogenesis exacerbate examined Express expression Factor growth hair hair follicle haploinsufficiency idea in vivo increased expression leads Lineage maintain maintenance mechanism Melanocyte melanocytes melanogenesis MITF mitigate Mouse models negative regulation observation overexpression pigment portion precursor Premature prevented progenitor raise regulated Regulation Regulatory role Sox10 STEM stem cell stem cells survival sustained target Transcription transcription factor transcription factors [DOI] 10.1371/journal.pgen.1003644 PMC 바로가기 [Article Type] Research Article
MK2-Dependent p38b Signalling Protects Drosophila Hindgut Enterocytes against JNK-Induced Apoptosis under Chronic StressMK2-의존성 p38b 신호는 만성 스트레스 하에서 JNK 유도 세포자멸사로부터 Drosophila Hindgut Enterocytes를 보호합니다Research Article Published on 2011-08-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence addressed affected antimicrobial peptides Apoptosis atrophy Author branch cascade Cell chronic complex component contribute damage damaged descendants Deterioration Diseases Drosophila Elimination Enterocyte enterocytes epithelial epithelium event form genetic analysis Gut Hindgut homeostasis Impaired induce integrity intestinal Intestinal diseases intestinal epithelium intestinal stem cell Intestinal stem cells JNK kinases leads less manifested pathogen Pathogens pathway peptides peptides) Prevent proliferation PROTECT Protective Protein protein kinase replaced REPLACED BY Replenishment required salt Signal transduction stem cell stem cells Stress Stressor stressors subsequent suppresse Trigger triggers upregulated upstream [DOI] 10.1371/journal.pgen.1002168 PMC 바로가기 [Article Type] Research Article
MicroRNome Analysis Unravels the Molecular Basis of SARS Infection in Bronchoalveolar Stem CellsResearch Article Published on 2009-11-132022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] ACE2 Activation acute infectious disease acute respiratory syndrome Basis bronchoalveolar caused CD45 Cell cellular miRNA complex interaction coronavirus SARS-CoV Data analysis Deterioration develop diagnostic Disease progression downregulated downregulation enrichment analysis epithelial evade Factors host cell host–virus interaction immune Infection inflammatory chemokines interact knowledge lung lung failure lung tissue marker microRNA miRNA miRNAs molecular mechanism Mortality observation pathway Protein target pulmonary fibrosis Replication reveal SARS-CoV SARS-CoV infection severe spike Stage STEM stem cell subset suppress target target cell the SARS epidemic Transmission viral genome Viral transmission virus [DOI] 10.1371/journal.pone.0007837 PMC 바로가기 [Article Type] Research Article