COVID-19 Pandemic and Trends in Clinical Trials: A Multi-Region and Global PerspectiveMedicine Published on 2021-12-242022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] calculated clinical clinical development clinical trial COVID-19 COVID-19 pandemic COVID-19 patient database decrease disease Drugs.com effort European Medicines Agency evaluate the effect First wave geographical region negative correlation new drug application Non-COVID-19 non-COVID-19 activity press prevalence of COVID-19 recognize releases reported statistically suggested the mean trend was increased [DOI] 10.3389/fmed.2021.812370 PMC 바로가기 [Article Type] Medicine
Provocation of dry eye disease symptoms during COVID-19 lockdownArticle Published on 2021-12-242022-10-29 Journal: Scientific Reports [Category] Coronavirus, SARS, [키워드] 95% CI age conducted contributed Corneal diseases COVID-19 COVID-19 outbreak cross-sectional demographics diagnosed disease disease symptom dropped elicited female gender First wave incidence information lockdown measure media mental health negative correlation participant questionnaire reported Risk factors SARS-CoV-2 significantly Symptom Symptoms the mean worsening [DOI] 10.1038/s41598-021-03887-4 PMC 바로가기 [Article Type] Article
Quantitative Analysis of SARS-CoV-2 Antibody Status between Patients with Cancer and Healthy Individuals with Extended Vaccination Dosing Intervals in Canada캐나다에서 연장된 백신 접종 간격을 가진 암 환자와 건강한 개인 간의 SARS-CoV-2 항체 상태의 정량적 분석Article Published on 2021-12-242022-09-12 Journal: Current Oncology [Category] SARS, 진단, [키워드] Analysis Anti-spike antibody antibody level AZD1222 binding antibody BNT162b2 Canada Cancer cancer patient Cancer patients Chemotherapy control group cross-sectional demonstrated domain dose Dosing ELISA enrolled enzyme-linked immunosorbent evaluate Extended group healthy hematological Hematological malignancy Humoral immunity IgG antibody individual interval knowledge mRNA-1273 Observed oncology participant Patient Protein response responses SARS-CoV-2 SARS-CoV-2 vaccine second dose serological serum significantly lower solid cancer solid cancer patients status the antibody response the healthy the mean the patient the SARS-CoV-2 therapy Treatment vaccination Vaccine [DOI] 10.3390/curroncol29010006 PMC 바로가기 [Article Type] Article
Evaluation of Hepatic Biochemical Parameters during Antiviral Treatment in COVID-19 PatientsArticle Published on 2021-12-232022-10-28 Journal: Biology [Category] COVID-19, [키워드] addition Admission affecting Alter analyzed Antigen Antiviral antiviral therapy Antiviral treatment antivirals biochemical cholestasis clinical Clinical practice Combination Community complex coronavirus COVID-19 COVID-19 disease diagnosed discharge drug evaluate Evolution hepatic hepatic parameters Hospitalization identify information Kaletra liver Liver damage liver enzyme Liver function Lopinavir/ritonavir observé Occurrence parameter Patient patients patients hospitalized produced producing Registered Repurposed drugs Romania RT-PCR SARS-CoV-2 viral infection SARS-CoV-2 virus Side effects Side-effect simple slight increase statistically target the disease the mean the SARS-CoV-2 virus therapeutic therapy treat treated Treatment [DOI] 10.3390/biology11010013 PMC 바로가기 [Article Type] Article
Immediate and Longer-Term Changes in the Mental Health and Well-being of Older Adults in England During the COVID-19 PandemicResearch Published on 2021-12-222022-10-30 Journal: JAMA Psychiatry [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] 95% CI accompanied age Ageing analyzed Anxiety anxiety symptom assessment Autonomy change changed changes changes in clinically cohort study Control COVID-19 COVID-19 pandemic Depression depressive symptom deteriorate Deterioration England English Evidence exposure finding Generalized greater group Health Immediate Importance increases in individual inequality initial introduced later phase less lockdown loneliness longitudinal longitudinal cohort study Los Angeles lowest measure Mental mental health mental health service National objective Older pandemic participant Participants pleasure Point poor quality Prevalence progressed provided psychological Impact Psychological intervention psychosocial stressor Quality of life regression models Relevance repeated Result Self-realization setting Sex significantly Sociodemographic characteristics Support tested the mean University of California Well-being white women [DOI] 10.1001/jamapsychiatry.2021.3749 PMC 바로가기 [Article Type] Research
Estimating the effect of timetabling decisions on the spread of SARS-CoV-2 in medium-to-large engineering schools in Canada: an agent-based modelling study캐나다 중대형 공학 학교에서 SARS-CoV-2의 확산에 대한 시간표 결정의 영향 추정: 에이전트 기반 모델링 연구Article Published on 2021-12-212022-09-11 Journal: CMAJ open [Category] 변종, [키워드] activity agent applied Combination conducted Contact Contact tracing Containment Course Coverage COVID-19 pandemic enrolment example Frequency implication Including Intervention involved Laboratory lectures less occurred online delivery outbreak proceed Randomized reduced reducing reduction in risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 variants School Spread Surveillance the mean transition transitioned universities vaccination were infected widespread [DOI] 10.9778/cmajo.20200280 PMC 바로가기 [Article Type] Article
The significant immune escape of pseudotyped SARS-CoV-2 variant Omicron유사형 SARS-CoV-2 변이체 오미크론의 유의미한 면역 탈출Coronaviruses Published on 2021-12-212022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Alpha BA.1 Beta convalescence serum Convalescent patients COVID-19 convalescent patient COVID-19 infection COVID-19 vaccines D614G Delta ED50 elicited finding Gamma Immune escape immune protection in vitro indicated infected with SARS-CoV-2 Lambda lead Mutation neutralization neutralization activity omicron Omicron variant other variant other variants Protein pseudotyped pseudotyped SARS-CoV-2 Pseudotyped virus reference strain SARS-CoV-2 SARS-COV-2 infection sensitivity sera serum sample serum samples Spike protein susceptibility the mean the Spike Vaccine variant variants variants of interest viruses VoC VOCs VOIs was tested [DOI] 10.1080/22221751.2021.2017757 PMC 바로가기 [Article Type] Coronaviruses
Household serial interval of COVID-19 and the effect of Variant B.1.1.7: analyses from prospective community cohort study (Virus Watch)Research Article Published on 2021-12-212022-10-28 Journal: Wellcome Open Research [Category] COVID-19, [키워드] affected analysed Analysis average B.1.1.7 B.1.1.7 variant caused cohort study Community COVID-19 COVID-19 pandemic England English Epidemiology estimate Evidence explain hotspot household illness Increased individual Infection National no significant difference positive positive swab previous study Receptor binding Region reported SARS-CoV-2 Serial interval Spread surveillance data tested the mean Transmissibility UK undergo variant of concern Viral load viral shedding VoC [DOI] 10.12688/wellcomeopenres.16974.2 PMC 바로가기 [Article Type] Research Article
Olfactory dysfunction as a screening tool for mild and moderate cases of COVID-19: a single-center prevalence study of 646 patients in flu clinicOriginal Article Published on 2021-12-202022-10-31 Journal: The Egyptian Journal of Otolaryngology [Category] COVID-19, [키워드] affected age analyzed Anosmia association calculate carried co-morbidity Contact cough COVID-19 COVID-19 infection COVID-19 patients diarrhea dysfunction evaluate female Fever flu Gustatory identify laboratory-confirmed malaise male Mild moderate myalgia nasal olfactory dysfunction Patient patients positive Prevalence prevalence study questionnaire reported Result SARS-CoV-2 single-center smell dysfunction study population Symptom Symptoms the mean was collected [DOI] 10.1186/s43163-021-00186-7 PMC 바로가기 [Article Type] Original Article
Impact of COVID-19 on routine malaria indicators in rural Uganda: an interrupted time series analysis우간다 시골 지역의 일상적인 말라리아 지표에 대한 코로나19의 영향: 중단된 시계열 분석Research Published on 2021-12-202022-10-30 Journal: Malaria Journal [Category] COVID-19, 말라리아, [키워드] absence analysed Analysis changes in collected COVID-19 COVID-19 epidemic COVID-19 pandemic decrease Diagnosis diagnostic disease Effect estimating equation expected expected values expressed Government Impact individual Interrupted lockdown malaria management MONITOR no difference occurred outcomes Patient performed Poisson regression predict Prevalence proportion Rapid diagnostic test RDT RDTs respond Result Rural health supplementary material Surveillance tested the mean Uganda was performed was used were recorded were used [DOI] 10.1186/s12936-021-04018-0 PMC 바로가기 [Article Type] Research