A Multiple-Hit Hypothesis Involving Reactive Oxygen Species and Myeloperoxidase Explains Clinical Deterioration and Fatality in COVID-19
Review
[키워드] activate
activated neutrophil
binding
clinical
Clinical deterioration
contribute
coronavirus disease
Coronavirus. COVID-19
COVID-19
COVID-19 patients
Critical
Critically ill
develop
explain
Factor
Free iron
hallmark
hemoglobin
HOCl
immune response
include
infections
Inflammation
Inflammatory
Involving
lung
lung mechanics
mechanism
microvascular injury
Mortality
MPO
myeloperoxidase
myeloperoxidase, HOCl
natural immune response
nitric oxide
oxidative
pathology
preserved
pulmonary hypertension
rapid clinical deterioration
reaction
Reactions
reactive oxygen species
reactive oxygen specy
ROS
severe COVID-19
severe hypoxemia
severe hypoxia
Specy
subsequent
therapeutic strategy
Thromboembolism
tissue damage
tissue injury
understanding
unique
vasoconstriction
[DOI] 10.7150/ijbs.51811 PMC 바로가기 [Article Type] Review
[DOI] 10.7150/ijbs.51811 PMC 바로가기 [Article Type] Review