Competing-risk analysis of coronavirus disease 2019 in-hospital mortality in a Northern Italian centre from SMAtteo COvid19 REgistry (SMACORE)Article Published on 2021-01-132022-10-04 Journal: Scientific Reports [Category] MERS, 바이오마커, 치료제, [키워드] age Analysis Care Clinical outcome Cohort competing coronavirus disease covariate COVID-19 cumulative died discharge discharged Diseases European evaluated function Gray Hospital admission hospitalisation hospitalised hospitalised patient ICU identify in-hospital mortality incidence independent risk factor Infectious diseases intensity IQR IRCCS Italian Italy lombardy male Male sex Matteo Mortality number of comorbidity Older age Patient patients patients with COVID-19 Pavia predicted predictor Regression risk transferred viral infection with COVID-19 [DOI] 10.1038/s41598-020-80679-2 PMC 바로가기 [Article Type] Article
Association Between Clinical Characteristics and Short-Term Outcomes in Adult Male COVID-19 Patients With Mild Clinical Symptoms: A Single-Center Observational StudyMedicine Published on 2021-01-052022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 2019 novel coronavirus age body temperature Care Characteristics Chest computed tomography chest imaging chest imaging study clinical clinical symptom Comorbidities conducted cough COVID-19 COVID-19 patient Critical develop diarrhea discharged disease disease deterioration elevated temperature enrolled fatigue follow-up period headache hemoptysis hospital identification Infection Laboratory test male mild clinical symptoms Mild symptom mild symptoms mobile cabin hospital nasal congestion nausea no significant difference observational study outcome outcomes oxygen saturation Patient performed Peripheral blood peripheral blood oxygen saturation Registration Shortness of breath sore throat sputum production transferred vomiting were recorded [DOI] 10.3389/fmed.2020.571396 PMC 바로가기 [Article Type] Medicine
Early Hemoperfusion for Cytokine Removal May Contribute to Prevention of Intubation in Patients Infected with COVID-19사이토카인 제거를 위한 조기 혈액 관류는 COVID-19에 감염된 환자의 삽관 예방에 기여할 수 있습니다Case Reports Published on 2021-01-012022-09-11 Journal: Blood purification [Category] SARS, 치료제, [키워드] Acute kidney injury acute respiratory distress acute respiratory distress syndrome AKI ARDS Complication Continuous Continuous renal replacement therapy COVID-19 CRRT cytokine Cytokines diagnosed with COVID-19 distress early stage early stages gradually declining Hemoperfusion hospital Hospitalized inflammatory mediator Inflammatory mediators intensive care intensive care unit intubation liver liver failure mediators Mortality multiple organ failure O2 Saturation oxygen oxygen mask Patient patients with COVID-19 Performing Prevent prevented prevention progression reached reduced removal renal renal replacement therapy replacement therapy respiratory distress Respiratory distress syndrome Septic shock syndrome the patient transferred Treatment with COVID-19 [DOI] 10.1159/000509107 PMC 바로가기 [Article Type] Case Reports
Low testosterone levels predict clinical adverse outcomes in SARS-CoV-2 pneumonia patients낮은 테스토스테론 수치는 SARS-CoV-2 폐렴 환자의 임상적 부작용을 예측합니다Article Published on 2021-01-012022-09-11 Journal: Andrology [Category] 바이오마커, [키워드] acute respiratory syndrome adverse outcome affected analyzed association baseline level biochemical Blood blood count C-reactive protein calculated Care Clinical outcome clinical outcomes Cohort cohort of patient condition coronavirus correlation CoV COVID-19 CRP D-dimer death defined diagnostic effective epidemiological data ferritin ferritin levels fibrinogen Gender Globulin group ICU IL-6 increase in Inflammatory inflammatory markers intensity intensive care interleukin interleukin 6 interleukin 6 (IL-6) Lactate lactate dehydrogenase LDH leukocyte Lower Luteinizing Hormone lymphocyte Lymphocyte count male Mantua material men Mortality mortality risk neutrophil neutrophil count pandemic Patient PCT Pneumonia poor prognosis positive predict procalcitonin Prognosis prognostic biomarker Prognostic biomarkers respiratory risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia Sex sex hormone sex hormone-binding globulin Sex hormones SHBG suggested Testosterone the SARS-CoV-2 transfer transferred women worsening [DOI] 10.1111/andr.12821 PMC 바로가기 [Article Type] Article
Tocilizumab for the Treatment of COVID-19-Induced Cytokine Storm and Acute Respiratory Distress Syndrome: A Case Series From a Rural Level 1 Trauma Center in Western PennsylvaniaCOVID-19 유발 사이토카인 폭풍 및 급성 호흡곤란 증후군 치료를 위한 토실리주맙: 서부 펜실베니아의 농촌 1급 외상 센터의 사례 시리즈Case Reports Published on 2021-01-012022-09-12 Journal: Journal of investigative medicine high impact case [Category] Coronavirus, 진단, [키워드] acute respiratory distress acute respiratory syndrome antibody ARDS case sery caused center Clinical improvement coronavirus coronavirus disease Coronavirus-2 cough COVID-19 COVID-19 patient cytokine Cytokine storm dose female Fever hospital Hospitalized Hyperinflammatory syndrome hypoxia ICU ICU admission intensive care interleukin-6 interleukin-6 receptor intravenous Intubated intubation level 1 life-threatening nasal nausea outbreak Oxygen requirement patients treated patients with COVID-19 Pneumonia respiratory Sery Shortness of breath Spread storm supplemental oxygen syndrome therapeutic Tocilizumab transferred transitioned treated worsening Wuhan, China [DOI] 10.1177/23247096211019557 PMC 바로가기 [Article Type] Case Reports
Heteromultivalent topology-matched nanostructures as potent and broad-spectrum influenza A virus inhibitors강력하고 광범위한 스펙트럼의 인플루엔자 A 바이러스 억제제로서의 이종 다가 토폴로지 일치 나노 구조Research Article Published on 2021-01-012022-09-14 Journal: Science Advances [Category] 진단, 치료기술, [키워드] acute respiratory syndrome binding binding site cellular coronavirus Coronavirus infection develop dose Effect host cell membrane Influenza influenza A virus inhibitor inhibitors inhibitory concentration Initially Prevent reduction SARS-CoV-2 synergistic the S protein Toxicity transferred virus virus entry virus propagation [DOI] 10.1126/sciadv.abd3803 PMC 바로가기 [Article Type] Research Article
Determining host factors contributing to disease severity in a family cluster of 29 hospitalized SARS-CoV-2 patients: Could genetic factors be relevant in the clinical course of COVID-19?입원한 29명의 SARS-CoV-2 환자 가족 클러스터에서 질병 중증도에 기여하는 숙주 요인 결정: 유전적 요인이 COVID-19의 임상 경과와 관련이 있을 수 있습니까?Article Published on 2021-01-012022-09-11 Journal: Journal of medical virology [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] age and gender baseline characteristics Clinical characteristics Clinical course Cluster Clusters Comorbidity consecutive patient consecutive patients contributing to coronavirus coronavirus disease coronavirus disease-2019 Course COVID-19 COVID-19 case COVID-19 cases determinant determine Determining Diagnosis disease course disease severity Factor Family cluster feature Genetic genetic mechanism group Hospital stay Hospitalized Host host susceptibility include Infection intensive care intensive care unit investigated Laboratory no difference outcome Patient patients hospitalized patients with SARS-CoV-2 Pneumonia presenting reported risk factor SARS-CoV-2 SARS-COV-2 infection screened severe disease severe pneumonia severity shown significantly significantly higher smoking statistically transferred Treatment two group two groups virus with COVID-19 [DOI] 10.1002/jmv.26106 PMC 바로가기 [Article Type] Article
Successful Treatment of Elderly Male With COVID-19 Infection With Severe Acute Respiratory Distress Syndrome Using Multimodal Therapy, Including Immune Modulation TherapyInfectious Disease Published on 2020-12-312022-10-31 Journal: Cureus [Category] COVID-19, [키워드] accompanied acute respiratory distress Administered antiviral therapy ARDS Computed tomography COVID-19 D-dimer level Deterioration Dexamethasone Diagnosis distal elderly explain Fever glycyrrhizin immune modulation immune modulation therapy Including initiated Injury Intravenous immunoglobulin intubation mechanical ventilation outcome oxygen Oxygenation Pneumonia polymerase chain reaction positive rehabilitation Remdesivir required respiratory Saliva suffered syndrome therapy tracheal transferred Treatment was obtained was performed [DOI] 10.7759/cureus.12402 PMC 바로가기 [Article Type] Infectious Disease
Emergency ventilator for COVID-19Research Article Published on 2020-12-302022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] ARDS Care component COVID-19 COVID-19 emergency COVID-19 pandemic COVID-19 patient death dimensions Emergency exceeded expiratory fatality Final functional hospital initial iteration mechanical ventilation mechanical ventilators organization Patient PEEP PIP positive Region respiratory Safe Support tested transferred treated ventilator was used [DOI] 10.1371/journal.pone.0244963 PMC 바로가기 [Article Type] Research Article
Global Infectious Disease Surveillance and Case Tracking System for COVID-19: Development StudyOriginal Paper Published on 2020-12-222022-10-31 Journal: JMIR Medical Informatics [Category] COVID-19, [키워드] addition affected application Blockchain Care Case report caused center Control country COVID-19 COVID-19 defense development disease transmission Diseases drug treatments effective effort facilitate global public health Health Health authority health care systems help HL7 FHIR hospital include Infectious disease Infectious disease surveillance information interface international collaboration interoperability Intervention labor-intensive laboratory data mechanisms medications new virus objective outcome pandemic Patient patient data patients with COVID-19 physician Physicians prevent disease spread prevention PROTECT provide receive recorded Research researcher respond Result reuse Spread Support Surveillance Symptoms System the disease Therapies this system transferred Transmission Treatment Trial utility virus was used [DOI] 10.2196/20567 PMC 바로가기 [Article Type] Original Paper