Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from HospitalResearch Published on 2004-10-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory syndrome analyzed antibody caused collected conjunctival convalescence cross-sectional determined discharged patient ELISA enzyme immunoassay immunofluorescence assay Indirect immunofluorescence assay MOST Novel coronavirus occurred Patient polymerase chain polymerase chain reaction positive Prevalence Research RNA SARS SARS-CoV Seroconversion seroconverted serology seropositive serum serum sample severe specimen Stool tested throat swab Two patient Urine Viral RNA virus was determined [DOI] 10.3201/eid1010.040026 PMC 바로가기 [Article Type] Research
Interferon-β 1a and SARS Coronavirus ReplicationResearch Published on 2004-02-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] 2003 acute respiratory syndrome antiviral drugs caused coronavirus Critical death effective effort identify in vitro inhibit Intensive interferon Novel coronavirus outbreak public health Replication SARS SARS Coronavirus therapy Treatment [DOI] 10.3201/eid1002.030482 PMC 바로가기 [Article Type] Research
Viral Discovery and Sequence Recovery Using DNA MicroarraysResearch Article Published on 2003-11-172022-10-28 Journal: PLoS Biology [Category] Coronavirus, [키워드] 2003 acute respiratory syndrome approach CENTRAL cloned Combination conserved coronavirus description detect DNA DNA microarray elements GenBank hybridized identify Infectious disease limitation Microarray new virus Novel coronavirus novel virus outbreak Pathogens physically platform SARS patient SARS virus sequence sequenced viral genome viral sequence virus virus genome [DOI] 10.1371/journal.pbio.0000002 PMC 바로가기 [Article Type] Research Article
Coronavirus-positive Nasopharyngeal Aspirate as Predictor for Severe Acute Respiratory Syndrome MortalityResearch Published on 2003-11-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory syndrome Analysis aspirate caused Chest compared Coronavirus infection death Diagnosis early Epidemic independent intensive care lactate dehydrogenase Lymphocyte count mechanical ventilation mortality rates nasopharyngeal Novel coronavirus Patient positive RT-PCR respiratory RT-PCR SARS virus severe Severe acute respiratory syndrome Shortness of breath significantly more Symptom [DOI] 10.3201/eid0911.030400 PMC 바로가기 [Article Type] Research
Early diagnosis of SARS Coronavirus infection by real time RT-PCRArticle Published on 2003-09-242022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, [키워드] 2003 assay collected develop Diagnosis diagnostic disease onset early early diagnosis early stage evaluate Infection Lancet Modification nasopharyngeal negative control sample negative controls NO Novel coronavirus positive protocol Quantitative quantitative PCR real time real time RT-PCR real-time RT-PCR respiratory Result RNA extraction RT-PCR RT-PCR assay Sample SARS Coronavirus SARS CoV SARS patient SARS-coronavirus sensitivity Serologically severe specimen tested viral RNA extraction [DOI] 10.1016/j.jcv.2003.08.004 PMC 바로가기 [Article Type] Article