Comparison five primer sets from different genome region of COVID-19 for detection of virus infection by conventional RT-PCROriginal Article Published on 2020-06-012022-10-31 Journal: Iranian Journal of Microbiology [Category] COVID-19, [키워드] Analysis analytical sensitivity beta-coronavirus caused changes in Characteristics coronavirus country COVID-19 detect envelope evaluated FIVE Genome genomic region high mutation rate identifying material ORF1ab outbreak PCR Positive predictive value prevalent primer primer set primer sets Primers protocol RdRP Region respiratory Reverse transcription-polymerase chain reaction RNA RT-PCR RT-PCR kit SARS-CoV-2 SARS-CoV-2 RNA selected sensitivity significant difference Specific primer specificity spike suggested the SARS-CoV-2 time viral nucleic acid virus virus infection was performed widespread Wuhan, China PMC 바로가기 [Article Type] Original Article
Pharmacologic Treatments and Supportive Care for Middle East Respiratory SyndromeSynopsis Published on 2020-06-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory distress syndrome antivirals benefit cell line clinical conducted convalescent plasma coronavirus Coronavirus infections Corticosteroids CoV Critical database death effective eligibility Evidence interferon Intravenous immunoglobulin membrane MERS MERS patient MERS patients Middle East Middle East respiratory syndrome moderate mortality rate MOST observational study Pharmacologic protocol reduced respiratory respiratory infections retrieved ribavirin RoB searched Severe acute respiratory syndrome suggested supportive care supportive therapies syndrome systematic review Therapies Treatment Trial unique viruses zoonoses [DOI] 10.3201/eid2606.200037 PMC 바로가기 [Article Type] Synopsis
The urgency of utilizing COVID-19 biospecimens for research in the heart of the global pandemicCommentary Published on 2020-06-012022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Asymptomatic biobanking biospecimen build complex confirmed case coronavirus Coronavirus disease 2019 COVID-19 death effort facilitate first outcome function genomic global pandemic help increasingly Infection New York New York City novel coronavirus disease outbreak pandemic pathology Patient positive presenting protocol real time Region regulated reported Research resource robust SARS-CoV-2 SARS-CoV-2 testing social distancing Spread Support tested translational translational medicine university urgency virus while [DOI] 10.1186/s12967-020-02388-8 PMC 바로가기 [Article Type] Commentary
Expert recommendations on blood purification treatment protocol for patients with severe COVID-19Research article Published on 2020-06-012022-10-05 Journal: Chronic Diseases and Translational Medicine [Category] 치료법, [키워드] Acute kidney injury acute respiratory syndrome addition adjust AKI Blood purification Blood purification treatment COVID-19 COVID-19 patient Cytokine storm defined diagnosed disease evaluate expected expert impairment implementation International key factor Middle East MONITOR Mortality outbreak parameter Patient patients with COVID-19 poor prognosis protocol public health emergency recommendation reducing Respiratory system SARS-CoV-2 severe COVID-19 severe disease subsequent syndrome the timing Treatment Treatment protocol World Health Organization Wuhan [DOI] 10.1016/j.cdtm.2020.04.002 [Article Type] Research article
Head and neck oncology during the COVID-19 pandemic: Reconsidering traditional treatment paradigms in light of new surgical and other multilevel risksReview article Published on 2020-06-012022-10-05 Journal: Oral oncology [Category] SARS, 치료법, [키워드] adverse outcomes aerosol generating procedure anticipated Cancer Care Cell COVID-19 COVID-19 infection COVID-19 pandemic deficiency favor Guidance HCW HCWs head head and neck cancer Head and neck oncology Health Health care worker immunosuppressive indicated management mucosal Mucosal squamous cell carcinoma Multilevel risk nosocomial COVID-19 novel Occurrence oncology operative Outbreaks Patient patients Personal protective equipment PPE protocol resource risk risk stratification Safe SARS-CoV-2 surgical Surgical barriers Surgical risk the patient therapy Traditional Transmission Treatment Treatment paradigms [DOI] 10.1016/j.oraloncology.2020.104684 [Article Type] Review article
Efficacy and safety of acupuncture therapy for COVID-19: Retracted A protocol for systematic review and meta-analysisResearch Article Published on 2020-05-292023-06-13 Journal: Medicine [Category] MERS, [키워드] acupuncture Coronavirus disease 2019 protocol systematic [DOI] 10.1097/MD.0000000000020407 PMC 바로가기 [Article Type] Research Article
Acute Neurological Care in the COVID-19 Era: The Pandemic Health System RE silience PROGRAM ( REPROGRAM ) Consortium PathwayNeurology Published on 2020-05-292022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] Acute stroke approach Care clinician condition conditions Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 Efficacy Evidence frontline healthcare worker guidelines healthcare worker highlight Intervention management mitigate neurointervention Neuroinvasive neurological pathway Patient patients Personal protective equipment Personal protective equipment (PPE) positive PPE protocol recommendation reperfusion risk of infection Safety stroke surgery System treated Variation virus [DOI] 10.3389/fneur.2020.00579 PMC 바로가기 [Article Type] Neurology
Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-ReviewCOVID-19 치료에 대한 클로로퀸 및 하이드록시클로로퀸 이독성의 임상적 의미: 미니 리뷰Review Published on 2020-05-292022-09-11 Journal: Frontiers in Public Health [Category] SARS, 치료제, [키워드] auditory Autoimmune diseases Characteristics Chloroquine clinical clinical trial clinical trials COVID-19 COVID-19 infection COVID-19 pandemic damage dose drug dysfunction Effect effective greater hearing loss Hydroxychloroquine hydroxychloroquine treatment Imbalance implication inner ear Intervention lAbel malaria Newborn off-label off-label use ototoxic ototoxicity pregnant women protocol reported sensorineural hearing loss structures suggested survivor tinnitus treated Treatment Trial urgent investigation usual dosage [DOI] 10.3389/fpubh.2020.00252 PMC 바로가기 [Article Type] Review
Prediction of Novel Inhibitors of the Main Protease (M-pro) of SARS-CoV-2 through Consensus Docking and Drug RepositionArticle Published on 2020-05-272022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV 3CL-Pro Algorithm Alprazolam antiviral drug approved drug AutoDock binding mode Carprofen Celecoxib Chymotrypsin-like protease COVID COVID-19 COVID-19 pandemic docked docking drug effective generate Glide high affinity in vitro inhibit inhibitor M-pro novel outbreak perampanel predict predicted prediction protease protocol Replication reposition responsible Sarafloxacin SARS Coronavirus SARS-CoV-2 Scientific community selected Spread the disease Treatment trovafloxacin Virtual screening virus [DOI] 10.3390/ijms21113793 PMC 바로가기 [Article Type] Article
Provision of obstetrics and gynaecology services during the COVID‐19 pandemic: a survey of junior doctors in the UK National Health ServiceOriginal Article Published on 2020-05-272022-10-28 Journal: BJOG : an international journal of obstetrics and [Category] COVID-19, MERS, SARS, [키워드] Abstract acute phase Analysis Antenatal Audit Care clinics coronavirus coronavirus disease Coronavirus disease 2019 COVID‐19 disrupting doffing donning evaluate gynaecology Health Service healthcare majority MOST National National Health Service not affected objective Obstetric obstetrics offered oncology pandemic participant pathway Population PPE protocol Quantitative analysis question reduced reduction in reported response Result Safe setting survey women women's health care [DOI] 10.1111/1471-0528.16313 PMC 바로가기 [Article Type] Original Article