Exploring active ingredients and function mechanisms of Ephedra-bitter almond for prevention and treatment of Corona virus disease 2019 (COVID-19) based on network pharmacologyResearch Published on 2020-11-102022-10-28 Journal: BioData Mining [Category] COVID-19, [키워드] 3CL ACE2 addition AutoDock binding binding activity biological processes caused Chinese Clinical practice collected component components Corona virus COVID-19 CTD disease docked Ephedra-bitter almond Epidemic functional enrichment GeneCard global pandemic immune responses ingredient inhibiting material mechanism molecular molecular docking molecular docking simulation molecular mechanisms of pharmacological action network pharmacology outbreak pathway PPI predicted Prevent Prospective Study protein-protein interaction provided Regulatory Result screened shown Structure supplementary material target targets TCMSP Traditional Chinese medicine treat Treatment virus were used [DOI] 10.1186/s13040-020-00229-4 PMC 바로가기 [Article Type] Research
Attitudes and precaution practices towards COVID-19 among pregnant women in Singapore: a cross-sectional surveyResearch Article Published on 2020-11-102022-10-28 Journal: BMC Pregnancy and Childbirth [Category] COVID-19, [키워드] 95% CI age Antenatal Attitude Attitudes Chinese clinician clinics Complete conducted COVID-19 COVID-19 outbreak cross-sectional cross-sectional survey demographical factor demographics employment frequencies Frequency global pandemic Google greater high risk higher risk independent Linear regression analysis majority measure Mental Multiple Multiple linear regression Neonatal non-infected outcome pandemic platform practices Precaution pregnant pregnant women provided psychological support question response Result Safe severe disease Singapore social distancing socio-demographic supplementary material survey variables was performed women [DOI] 10.1186/s12884-020-03378-w PMC 바로가기 [Article Type] Research Article
EAES Recommendations for Recovery Plan in Minimally Invasive Surgery Amid COVID-19 PandemicEAES Recommendations Published on 2020-11-102022-10-28 Journal: Surgical endoscopy [Category] COVID-19, SARS, [키워드] abdominal wall activity addressed approved clinical setting clinician Community Consensus COVID-19 COVID-19 crisis COVID-19 pandemic defined DelPhi Delphi consensus domains EAES guidance eight Endocrine Evidence Healthcare systems minimally invasive surgery MIS Modification plan priority question recommendation representing Research Result resulting Safe supplementary material surgery surgical was performed [DOI] 10.1007/s00464-020-08131-0 PMC 바로가기 [Article Type] EAES Recommendations
Attitudes and concerns of undergraduate university health sciences students in Croatia regarding complete switch to e-learning during COVID-19 pandemic: a surveyResearch Article Published on 2020-11-102022-10-28 Journal: BMC Medical Education [Category] COVID-19, SARS, [키워드] adjusted affected Attitude average collected Complete coronavirus COVID-19 COVID-19 pandemic Croatia education enrolled Health Science Health Sciences help IMPROVE indicated lack medical education MOST pandemic participant Participants questionnaire reported Result SARS-CoV-2 SARS-COV-2 infection Satisfaction School supplementary material [DOI] 10.1186/s12909-020-02343-7 PMC 바로가기 [Article Type] Research Article
Structured ICU resource management in a pandemic is associated with favorable outcome in critically ill COVID‑19 patientsMain Topic Published on 2020-11-102022-10-29 Journal: Wiener Klinische Wochenschrift [Category] COVID-19, SARS, [키워드] Acute kidney injury acute respiratory syndrome adaptive age cohort study Comorbidity complex coronavirus COVID-19 Critically ill Critically ill patient Date extracorporeal membrane oxygenation Final first symptom Follow-up hospital Hospital stay ICU ICU admission intensive care interquartile range Invasive mechanical ventilation IQR LOS majority male management measure mechanical ventilation median Mortality no significant difference outcome Patient patients positive Rapid receiving required resource resources Result SARS-CoV-2 SARS-CoV‑2 Severity of disease state still hospitalized supplementary material tested therapy Treatment were recorded with COVID-19 [DOI] 10.1007/s00508-020-01764-0 PMC 바로가기 [Article Type] Main Topic
Kinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19: a descriptive studyResearch Article Published on 2020-11-102022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] absorbed antibody Antibody Response Antibody response and qRT-PCR Antibody titer changes in China Clinical course COVID-19 COVID-19 patient detectable enrolled FIVE help hospital Hospitalized IgG IgM Infection kinetic Laboratory lung Lung image N proteins occurred Pathogenesis Patient patients patients with COVID-19 peaked positive RBD Receptor binding domain remained Result returned RNA SARS-CoV-2 serum severe inflammation Stool supplementary material Swab viral infection Viral RNA were assessed Zhejiang [DOI] 10.1186/s12879-020-05549-8 PMC 바로가기 [Article Type] Research Article
Venous thromboembolism and COVID-19: a single center experience from an academic tertiary referral hospital of Northern ItalyObservational Study Published on 2020-11-082022-10-04 Journal: Internal and Emergency Medicine [Category] MERS, 임상, [키워드] Anticoagulants anticoagulation anticoagulation treatment association C reactive protein clinical suspicion co-morbidities conducted correlated COVID-19 patient COVID-19 patients CRP d -dimer defined develop Hospital admission IL-6 Inflammatory inflammatory status information inverse correlation Italy Laboratory tests lactate dehydrogenase LDH magnitude majority male Patient patients Platelet positive correlation predictor preliminary evidence Prevalence pro-inflammatory cytokine Prophylaxis Pulmonary embolism raise Record retrospective risk factor SARS-CoV-2 Serum level significant difference significantly significantly higher single center supplementary material Support susceptibility tertiary referral hospital Thromboembolism thrombosis Venous Thromboembolism Volume VTE [DOI] 10.1007/s11739-020-02550-6 PMC 바로가기 [Article Type] Observational Study
COVID-19 in cancer patients: clinical characteristics and outcome—an analysis of the LEOSS registry암 환자의 COVID-19: 임상 특성 및 결과 - LEOSS 레지스트리 분석Multicenter Study Published on 2020-11-072022-09-10 Journal: Annals of Hematology [Category] MERS, SARS, 치료기술, [키워드] active malignancy Adjusted analysis advanced age age age distribution Analysis analyzed anti-cancer treatments assumed Cancer cancer patient Cancer patients Clinical characteristics Cohort cohort study collected Comorbidities Comorbidity comparable conditions Course COVID-19 death rates determine distribution Endpoint enrolled European feature female higher risk ICU admission Infection LEOSS leukemia lymphoma majority Male sex malignancy mild symptoms Mortality mortality rate open outcome p value pandemic Patient patients primary endpoint Result Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic severe COVID-19 Sex significantly Solid solid tumors supplementary material survey the early SARS-CoV-2 Tumor tumors was performed [DOI] 10.1007/s00277-020-04328-4 PMC 바로가기 [Article Type] Multicenter Study
COVID-19 and the return to head and neck outpatient activity in the United Kingdom: what is the new normal?Short Communication Published on 2020-11-062022-10-31 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID-19, SARS, [키워드] aerosol-generating procedure Air change per hour change clinics COVID-19 cross-sectional equipment flexible head healthcare hour language maintain majority Maxillofacial measure natural ventilation Neck NHS oncologist otolaryngology outpatient clinic participant Patient patient safety patients Protective protocol protocols ranged reduction in Responder Result Risk assessment room salt significant increase speech supplementary material surgical Trust United Kingdom Variation web-based platform [DOI] 10.1007/s00405-020-06458-x PMC 바로가기 [Article Type] Short Communication
Pulmonary embolism in patients with COVID-19: characteristics and outcomes in the Cardio-COVID Italy multicenter studyOriginal Paper Published on 2020-11-032022-10-31 Journal: Clinical Research in Cardiology [Category] COVID-19, [키워드] d-dimer 95% CI Abstract Admission age Anticoagulant association baseline bleeding bleeding event BMI Cardiology Characteristics Chronic kidney disease Coagulopathy Cohort Concentration coronavirus disease COVID-19 COVID-19 patient critically ill patients cubic spline d -dimer death described discharge evaluated Evidence Follow-up hazard heart failure heterogeneous hospitalized COVID-19 patients implication In-hospital death in-hospital mortality incidence investigated Italy less linear males multicenter occur outcome Patient proportion Pulmonary embolism regression analysis Result subject supplementary material Support those without PE Thromboembolism Tocilizumab two subject unit variable Ventilated Ventilation [DOI] 10.1007/s00392-020-01766-y PMC 바로가기 [Article Type] Original Paper