Increasing accessibility in COVID-19 clinical trialsNews Published on 2020-05-012022-10-05 Journal: The Lancet. Microbe [Category] 임상, [키워드] clinical trial COVID-19 Increasing [DOI] 10.1016/S2666-5247(20)30015-X [Article Type] News
Does the COVID-19 outbreak identify a broader need for an urgent transformation of cancer clinical trials research?Correspondence Published on 2020-05-012022-10-05 Journal: Contemporary clinical trials [Category] SARS, 임상, [키워드] Cancer Cancer disparities clinical trial clinical trials COVID-19 COVID-19 outbreak identify [DOI] 10.1016/j.cct.2020.105997 [Article Type] Correspondence
Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patientsReview Published on 2020-05-012022-10-28 Journal: Theranostics [Category] COVID-19, MERS, SARS, [키워드] addition administration approved benefit carrier caused cells clinical trial Concentration coronavirus 2 COVID-19 disease drug drug delivery systems drugs effective expected globe help immune indication Infection Infectious disease intranasal investigated mucosal nanomedicine noninvasive offer overcome peptide pulmonary diseases reported respiratory SARS-CoV-2 Side effect SIREN siRNA specific treatment theranostic nanoparticles therapeutic therapeutic agent treating COVID-19 patient Treatment response Vaccines while World Health Organization [DOI] 10.7150/thno.46691 PMC 바로가기 [Article Type] Review
Secondary Impact of the COVID-19 Pandemic on Patients With Heart FailureArticle Published on 2020-05-012023-07-14 Journal: Circulation. Heart failure [Category] SARS, [키워드] clinical trial coronavirus heart failure poverty social isolation Telemedicine [DOI] 10.1161/CIRCHEARTFAILURE.120.007219
Cardiovascular Impairment in COVID-19: Learning From Current Options for Cardiovascular Anti-Inflammatory TherapyCardiovascular Medicine Published on 2020-04-302022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] addition Algorithm Anti-inflammatory therapy cardiovascular cardiovascular anti-inflammatory therapy cardiovascular disease cardiovascular diseases cardiovascular impairment caused China clinical trial clinical trials Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients current Cytokine storm Direct Drug screening Efficacy and safety ENhance feature global pandemic high risk IL-1β IL-6 impairment in vitro Inflammation Inflammatory learning management mechanism mitigate MODS multiple organ dysfunction occurred option outcomes pathway positive preclinical study proceed profiles Prognosis Protective reduce SARS-CoV-2 Severe case syndrome Th1 Th2 response TNF-α translation Treatment treatments of COVID-19 viral infection [DOI] 10.3389/fcvm.2020.00078 PMC 바로가기 [Article Type] Cardiovascular Medicine
COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?Research Perspective Published on 2020-04-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, MERS, SARS, [키워드] ACE-2 age aging angiotensin-converting enzyme 2 antibiotic Antibiotics association Azithromycin Beta-galactosidase CD26 cellular China clinical trial Compound Corona virus COVID-19 COVID-19 disease COVID-19 infection disease doxycycline drug Drug repurposing FDA-approved drugs functional host receptor Hydroxy-chloroquine Hypothesis IL-6 inhibit inhibitor marker MERS Middle East mortality rate Other pandemic Patient preventing the transmission prevention prevention of COVID-19 profiles protein synthesis quercetin question Rapamycin respiratory resulting SARS-CoV-2 SASP senescence senolytic drug therapy Side-effect Spread Treatment viral replication virus zoonotic [DOI] 10.18632/aging.103001 PMC 바로가기 [Article Type] Research Perspective
Indications regarding the management of interventional clinical trials with drugs during the current COVID-19 emergency in ItalyEditorial Published on 2020-04-302022-10-05 Journal: ESMO open [Category] SARS, 임상, [키워드] clinical trial clinical trials COVID-19 COVID-19 emergency drug indication Italy management oncology SARS-CoV2 [DOI] 10.1136/esmoopen-2020-000782 [Article Type] Editorial
Confronting Covid-19 by exploring the possibility of vaccinating with live SARS-CoV-2 virus itself, via a route that would reduce the incidence of pulmonary complications폐 합병증 발병률을 줄이는 경로를 통해 살아있는 SARS-CoV-2 바이러스 자체의 예방 접종 가능성을 탐색하여 Covid-19에 맞서기Opinion Article Published on 2020-04-292022-09-11 Journal: F1000Research [Category] MERS, SARS, 비임상, [키워드] Aerosols airway animal model animal models breath bypassing can be used cats cellular clinical trial components conducted Contagiosity Course digestive digestive tract Effectiveness experiment ferret ferrets hamsters help Hope immune responses Immune status incidence infections inoculation intra-peritoneal lead leads less live SARS-CoV-2 Lungs macaques matter priority profiles pulmonary complication pulmonary complications Pulmonary pathology recipient recipients reduce reduced released resulting risk route SARS-CoV-2 SARS-CoV-2 virus serological Skin test step subjects tested the SARS-CoV-2 virus vaccination vector Viral viral replication virus Volunteer [DOI] 10.12688/f1000research.23480.1 PMC 바로가기 [Article Type] Opinion Article
Clinical characteristics of 145 patients with corona virus disease 2019 (COVID-19) in Taizhou, Zhejiang, ChinaOriginal Paper Published on 2020-04-282022-10-29 Journal: Infection [Category] COVID-19, MERS, SARS, [키워드] age anorexia average bilateral pneumonia body mass index center Characteristics Chest China clinical Clinical characteristics Clinical data clinical trial common Comorbidity Corona corona virus disease 2019 COVID-19 Diabetes Mellitus diarrhea Dizziness dry cough Dyspnea electronic medical records enrolled Epidemiology fatigue Fever ground-glass opacity hospitalized patient ill patient ill patients imaging examination Invasive mechanical ventilation men nasal obesity objective Older outcomes Oxygen therapy Patient patients with comorbidity Pneumonia proportion Public Result retrospective SARS-CoV-2 severely ill patient severely ill patients single center Standard deviation Symptom Treatment Virus Disease was performed with COVID-19 Zhejiang [DOI] 10.1007/s15010-020-01432-5 PMC 바로가기 [Article Type] Original Paper
Addressing COVID‐19 Drug Development with Artificial IntelligenceEssay Published on 2020-04-272022-10-28 Journal: Advanced Intelligent Systems (Weinheim an Der Bergstrasse, Germany) [Category] COVID-19, [키워드] acute respiratory syndrome antibodies antibody approach approaches artificial artificial intelligence cause clinical trial Combination combination therapies combination therapy composed coronavirus COVID-19 COVID‐19 development drug drug combination Drug development Drug screening Efficacy effort ENhance evaluated Healthcare system identify Inc include Infectious disease intelligence Moderna Multiple outcomes pandemic pathogen Phase I regimen repurposed therapies SARS‐CoV‐2 severe acute respiratory syndrome coronavirus 2 sustained therapy timeline Treatment turn Vaccine Vaccine development Vaccines virus widespread [DOI] 10.1002/aisy.202000070 PMC 바로가기 [Article Type] Essay