clinical trial – Page 239 – Communicable Diseases Research

A Review of SARS-CoV-2 and the Ongoing Clinical Trials

Review

Published on 2020-04-102022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS,

[키워드] 2019 novel coronavirus 2019-nCoV ACE2 affecting alleviate antibody antimalarial antiviral drug antiviral immune response approach boost categories Characteristics clinical Clinical data Clinical features clinical study clinical trial clinical trials coronavirus COVID-19 COVID-19 pandemic Data analysis disease drugs dysregulated effective endosomal entry pathway epidemiological Epidemiology Favipiravir feature global pandemic Healthcare system high variability Hydroxychloroquine Immunotherapy Inflammatory responses initial initiated interfere MERS-CoV Middle East molecular outbreak pandemic pathology Pneumonia rapid response replicase respiratory syndrome coronavirus review SARS-CoV SARS-CoV-2 tested therapeutic therapeutic agent therapeutic potential Treatment Trial Vaccine viral replication virulent virus virus infection virus replication Wuhan Wuhan, China
[DOI] 10.3390/ijms21072657 PMC 바로가기 [Article Type] Review

COVID-19: A Brief Overview of the Discovery Clinical Trial

Opinion

Published on 2020-04-102022-10-28
Journal: Pharmaceuticals [Category] COVID-19,

[키워드] antivirals Chloroquine clinical clinical trial COVID-19 curative drug European favor Hydroxychloroquine Lopinavir/ritonavir outbreak Remdesivir repurposing SARS-CoV-2 Treatment urgency WHO
[DOI] 10.3390/ph13040065 PMC 바로가기 [Article Type] Opinion

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

Research

Published on 2020-04-092022-10-05
Journal: Nature [Category] SARS, 신약개발, 치료제,

A new clinical trial to test high-dose vitamin C in patients with COVID-19

Letter

Published on 2020-04-072022-11-01
Journal: Critical Care [Category] Coronavirus, SARS,

[키워드] clinical trial High-dose vitamin C patients with COVID-19
[DOI] 10.1186/s13054-020-02851-4 PMC 바로가기 [Article Type] Letter

Antiviral therapy in management of COVID-19: a systematic review on current evidence

Review Article

Published on 2020-04-062022-10-27
Journal: Archives of Academic Emergency Medicine [Category] COVID-19,

A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19)

Infectious Disease

Published on 2020-04-062022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] ACE ACE2 Angiotensin-converting enzyme ARDS Basic science Biochemistry can be used candidate CDC center Chloroquine clinical Clinical course Clinical practice clinical trial Comprehensive Control Coronavirus disease 2019 Corticosteroid COVID-19 COVID19 described diagnostic discharge disease course epidemiological evaluate evaluated Evolution experiment explain Factor Frequency global pandemic H1N1 hindrance hospital ibuprofen Infection information inhibitors limitation literature literature review LOPINAVIR AND RITONAVIR management manuscript media MERS Micronutrient mRNA-1273 vaccine multiple parameter nonsteroidal anti-inflammatory drug NSAIDS outbreak pandemic Phylogeny presentation Prophylaxis Public health interventions remdesivir (GS-5734) review risk factor SARS-CoV-2 self-quarantine severe acute respiratory infection Spread statistical Stratification Symptom the SARS-CoV-2 virus the WHO therapy Treatment viral genome virion Vitamin C
[DOI] 10.7759/cureus.7560 PMC 바로가기 [Article Type] Infectious Disease

Driving forces for COVID-19 clinical trials using chloroquine: the need to choose the right research questions and outcomes

Letter

Published on 2020-04-062022-10-28
Journal: Revista da Sociedade Brasileira de Medicina Tropic [Category] COVID-19, MERS, SARS,

[키워드] clinical trial COVID-19 outcome Research question
[DOI] 10.1590/0037-8682-0155-2020 PMC 바로가기 [Article Type] Letter

Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths

Review

Published on 2020-04-022022-10-30
Journal: Nutrients [Category] COVID-19, SARS,

[키워드] 25-hydroxyvitamin D acute respiratory distress acute respiratory distress syndrome (ARDS) addition age anti-inflammatory cytokines ascorbic acid Cathelicidin chronic disease clinical trial Comorbidity Concentration concentrations conducted contribute Controlled trial coronavirus COVID-19 COVID-19 pandemic Cytokine storm death deficiency dose Epidemiology evaluate Health include infected with COVID-19 Inflammation Influenza knowledge Lungs measure mechanism mechanisms Observational observational study occurred outbreak Pneumonia prevention pro-inflammatory cytokine Public quarantine raise recommendations reduce reduced reducing reported respiratory tract infection Respiratory tract infections risk risk of COVID-19 risk of infection risk of infections solar radiation southern hemisphere Treatment UVB viral replication Vitamin C Vitamin D Vitamin D supplementation
[DOI] 10.3390/nu12040988 PMC 바로가기 [Article Type] Review

Minimum costs to manufacture new treatments for COVID-19

Research article

Published on 2020-04-012022-10-05
Journal: Journal of Virus Eradication [Category] 신약개발, 치료법,

Clinical observation and management of COVID-19 patients

Commentary

Published on 2020-03-252022-10-31
Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS,