Characteristics of Helicase-Primase Inhibitor Amenamevir-Resistant Herpes Simplex VirusAntiviral Agents Published on 2021-07-062024-09-04 Journal: Med Instrum [Category] 대상포진, [키워드] amenamevir Antiviral agents Helicase-primase complex HSV-1 HSV-2 UL5 UL52 [DOI] 10.1128/AAC.00494-21 PMC 바로가기 [Article Type] Antiviral Agents
Targeting TLR4 Signaling to Blunt Viral-Mediated Acute Lung Injury둔기 바이러스 매개 급성 폐 손상에 대한 TLR4 신호 표적화Review Published on 2021-07-022022-09-11 Journal: Frontiers in Immunology [Category] SARS, 치료제, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome addition ALI antiviral agent Antiviral agents antiviral treatments approach ARDS caused circulating Consequences Critical cytokine Cytokine storm DAMPs danger-associated molecular pattern death effective Efficacy HMGB1 Hospitalization Infection Inflammatory response Influenza influenza infection influenza infections initiated innate immune response Interaction lead lethal infection life life threatening Local Lung injury PAMPs Pandemics pathogen pathogen-associated molecular pattern pathogen-associated molecular patterns Pathogens Pattern recognition pattern recognition receptor Pattern recognition receptors predicted PRRs respiratory respiratory distress Respiratory distress syndrome respiratory viral infections SARS-CoV-2 pandemic Signaling strain Symptom syndrome targeting TLR4 Treatment triggered uncontrolled Vaccine Viral viral infection viral infections Viral resistance virus viruses while [DOI] 10.3389/fimmu.2021.705080 PMC 바로가기 [Article Type] Review
A tale of two diseases: Sarcoidosis, COVID-19 and new therapeutic options with dual RAS inhibition and tetanus-diphtheria vaccineResearch article Published on 2021-07-012022-10-05 Journal: Medical Hypotheses [Category] SARS, 치료제, [키워드] ACE2 ACE2 binding Anergy angiotensin antibodies antigenic Antiviral agents ARDS beta coronavirus CD4+ CD4+ T cell CD8+ T cell Cell Combination COVID-19 described dysfunction Hydroxychloroquine immune dysregulation immune response lung Mortality natural killer overcome pathogen problem RAS RAS inhibition Re-infections receptor renin-angiotensin system response responsible sarcoidosis SARS CoV-2 similarity target Tetanus-diphtheria vaccine the disease the patient therapeutic option therapeutic strategy turn Vaccine [DOI] 10.1016/j.mehy.2021.110619 [Article Type] Research article
Antiviral zinc oxide nanoparticles mediated by hesperidin and in silico comparison study between antiviral phenolics as anti-SARS-CoV-2헤스페리딘에 의해 매개되는 항바이러스성 산화아연 나노입자와 항-SARS-CoV-2로서의 항바이러스성 페놀계 물질 간의 in silico 비교 연구Article Published on 2021-07-012022-09-11 Journal: Colloids and surfaces. B, Biointerfaces [Category] SARS, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition Analysis anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity Antiviral antiviral activity antiviral agent Antiviral agents assist caused characterized complementary Compound coronavirus COVID-19 curative death docking score evaluated example HAV Hepatitis hepatitis A hepatitis A virus hesperidin highest in silico Infection Isolation leads measure metabolite molecular docking nutraceutical nutraceuticals pandemic pharmaceutical Potential treatment predicted protocol protocols reducing reducing agent required respiratory responsible RNA viruses Safe SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Side effects synthesis TEM tested Treatment virus Zinc zinc oxide zinc oxide nanoparticles [DOI] 10.1016/j.colsurfb.2021.111724 PMC 바로가기 [Article Type] Article
A toddler diagnosed with severe postinfectious bronchiolitis obliterans and COVID-19 infection중증 폐쇄성 세기관지염 및 COVID-19 감염 진단을 받은 유아Comment Published on 2021-07-012022-09-11 Journal: Pediatric pulmonology [Category] SARS, 치료제, [키워드] Antiviral Antiviral agents Antiviral treatment Asthma benefit Bronchiolitis bronchiolitis obliterans children chronic lung disease Clinical improvement Comorbidities compassionate use Corticosteroids COVID-19 COVID-19 infection COVID-19 pandemic diagnosed Efficacy evaluated incidence Lung disease management morbidity outcome pathophysiologic pediatric pediatric cohort Postinfectious pulmonary conditions reduce Remdesivir SARS-COV-2 infection shown Treatment underlying respiratory condition underlying respiratory conditions [DOI] 10.1002/ppul.25436 PMC 바로가기 [Article Type] Comment
Use of chlorhexidine to eradicate oropharyngeal SARS-CoV-2 in COVID-19 patientsCOVID-19 환자에서 구인두 SARS-CoV-2를 근절하기 위한 클로르헥시딘의 사용Randomized Controlled Trial Published on 2021-07-012022-09-11 Journal: Journal of medical virology [Category] SARS, 임상, 치료제, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition antimicrobial agent Antiviral Antiviral agents chlorhexidine Chlorhexidine gluconate Combination control group control patients coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient disease spread Disinfectants dissemination distribution eliminated Epidemiology hospitalized COVID-19 patients investigated laboratory-confirmed Oropharyngeal oropharynx Patient patients presence or absence Primary outcome prospective cohort study Randomized reducing Safe SARS-CoV-2 severe acute respiratory syndrome Coronavirus shedding Spread Standard of care study group Vaccine [DOI] 10.1002/jmv.26954 PMC 바로가기 [Article Type] Randomized Controlled Trial
Clinical efficacy of antiviral agents against coronavirus disease 2019: A systematic review of randomized controlled trialsReview Published on 2021-06-262023-07-01 Journal: Journal of microbiology, immunology, and infection [Category] SARS, [키워드] Antiviral agents COVID-19 Efficacy SARS-CoV-2 [DOI] 10.1016/j.jmii.2021.05.011 PMC 바로가기 [Article Type] Review
Targeting the Conserved Stem Loop 2 Motif in the SARS-CoV-2 GenomeSARS-CoV-2 게놈에서 보존된 줄기 루프 2 모티프 표적화Article Published on 2021-06-242022-09-12 Journal: Journal of Virology [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome Antisense oligonucleotide Antisense oligonucleotides Antiviral Antiviral agents ASO assays astrovirus Cell culture cleavage conserved coronavirus Coronaviruses dose-dependent manner element gapmer Genome inhibit inhibit SARS-CoV-2 LNA loop motif noroviruses occur Occurrence oligonucleotides picornavirus plus-strand RNA virus Replication reporter Research RNA RNA viruses s2m SARS-CoV SARS-CoV-2 Sequence conservation single-stranded positive-sense STEM subgenomic transcript targeting the SARS-CoV-2 therapeutic therapeutic oligonucleotides. UTR variety viral infection [DOI] 10.1128/JVI.00663-21 PMC 바로가기 [Article Type] Article
A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov천연 식물 화합물을 사용한 바이러스 질환에 대한 잠재적 치료에 대한 간단한 개요 : SARS-COV의 경우Review Published on 2021-06-242022-08-31 Journal: Molecules [Category] SARS, 치료제, [키워드] Analysis Antiviral antiviral activity Antiviral agents Antiviral compounds applied bioactive compounds chemical compounds combat complex Compound compounds coronavirus COVID-19 pandemic Culture disease effective Hairy hairy roots help herbal medicine herbal medicines highlight in silico in vitro increase in Infectious disease Infectious diseases life-threatening mechanism molecular molecular docking studies molecular farming natural plant plant compound plant compounds plant extracts plants Potential researcher respiratory diseases shown Treatment Viral Viral diseases viral infections virus viruses [DOI] 10.3390/molecules26133868 PMC 바로가기 [Article Type] Review
Convalescent Plasma for Pregnant Women with COVID-19: A Systematic Literature ReviewCovid-19를 가진 임산부를위한 회복기 혈장 : 체계적인 문헌 검토Review Published on 2021-06-222022-09-10 Journal: Viruses [Category] MERS, 치료제, [키워드] Administered antiviral agent Antiviral agents benefit Case report case reports clinical Clinical improvement clinical trial registries clinical trial registry clinical trials Clinical use convalescent plasma COVID-19 criteria Critical Critically ill database described discharged duplications during pregnancy Effect eligible Elimination Evidence excluded fetus Google Scholar Hyperimmune plasma inclusion criteria information initial search literature morbidity mother Neonates Newborn outcome oxygen preeclampsia pregnancies Pregnancy pregnant women provide rehabilitation reported reporting bias review SARS-CoV-2 SARS-COV-2 infection Science searched severe COVID-19 survival systematic review teratogenic teratogenic effects Treatment treatment of COVID-19 Trial was used Web with COVID-19 [DOI] 10.3390/v13071194 PMC 바로가기 [Article Type] Review