Effect of plasma exchange on COVID-19 associated excess of von Willebrand factor and inflammation in critically ill patients Research Published on 2022-03-212022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] accompanied acute respiratory distress ADAMTS13 Antigen ARDS benefit C-reactive protein clinical parameter COVID-19 Critically ill patient cytokine Effect excess expiratory hospitals immunothrombosis Inflammation Inflammatory Inflammatory cytokine inflammatory state investigated lactate dehydrogenase monocyte chemotactic protein-1 on mechanical ventilation parameter parameters pathogenesis of COVID-19 Patient patients plasma plasma exchange Pneumonia positive reduce reduced reduction resulting sequence severe COVID-19 significant decrease significant increase significantly syndrome therapeutic option therapy vasculature Ventilation von Willebrand factor were assessed [DOI] 10.1038/s41598-022-08853-2 [Article Type] Research
Monitoring respiratory mechanics by oscillometry in COVID-19 patients receiving non-invasive respiratory supportObservational Study Published on 2022-03-212022-10-05 Journal: PLoS ONE [Category] 임상, 치료기술, [키워드] acute respiratory distress Admission affected ARDS changes in Comorbidities Comorbidity complementary COVID 19 patient COVID 19 patients COVID-19 patient COVID-19 patients Deterioration discharge evaluate feasibility feasible hospital identify increasingly information intensive care unit invasive ventilation Italy less lung mechanics management Measures moderate-severe monitoring more difficult NIV Non-invasive respiratory support not correlated Oxygenation parameter Patient patients physiological pilot study receiving recruited respiratory Respiratory mechanics syndrome Treatment Trieste university Ventilation [DOI] 10.1371/journal.pone.0265202 PMC 바로가기 [Article Type] Observational Study
Plasma Markers of Neutrophil Extracellular Trap Are Linked to Survival but Not to Pulmonary Embolism in COVID-19-Related ARDS Patients호중구 세포외 트랩의 혈장 표지자는 COVID-19 관련 ARDS 환자의 생존과 관련이 있지만 폐색전증과는 관련이 없습니다Article Published on 2022-03-172022-09-11 Journal: Frontiers in Immunology [Category] MERS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome Admission Analysis ARDS Biomarker circulating Clinical outcome clinical outcomes collected Comparisons complexes coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression develop Embolism evaluate Extracellular hospital hospitalized COVID-19 patient hospitalized COVID-19 patients Hypothesis immunothrombosis life-threatening lung damage Mann-Whitney test marker microthrombus moderate disease myeloperoxidase NET NETosis NETs neutrophil Neutrophil extracellular trap Neutrophil extracellular traps non-survivor Non-survivors Occurrence Patient patients patients hospitalized plasma Plasma levels Prevent pulmonary Pulmonary embolism recent respiratory distress Respiratory distress syndrome responsible restriction severe COVID-19 patients severe disease severe patients survival survivor syndrome therapeutic target total DNA TRAP were assessed with COVID-19 worsening [DOI] 10.3389/fimmu.2022.851497 PMC 바로가기 [Article Type] Article
A Case Report for Using Methylprednisolone for Severe ARDS Caused by SARS-CoV-2 Delta Variant in a Pediatric Patient With Lennox-Gastaut SyndromeLennox-Gastaut 증후군이 있는 소아 환자에서 SARS-CoV-2 Delta 변이로 인한 중증 ARDS에 대한 Methylprednisolone 사용에 대한 증례 보고서Case Reports Published on 2022-03-142022-09-11 Journal: Journal of Korean medical science [Category] SARS, 변종, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered ARDS B.1.617.2 caused children Comorbidities Comorbidity coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease-19 Coronavirus disease-19 (COVID-19) COVID-19 Delta End-Expiratory Pressure Expiratory Pressure extubation Fever high fever high-dose methylprednisolone hospital increased risk intractable Lennox-Gastaut Syndrome Methylprednisolone neurologic observation Oxygenation pandemic Pediatric patient Pediatric patients Positive end-expiratory pressure report reported required respiratory respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-CoV-2 delta Seizure Seizures severe acute respiratory syndrome Coronavirus severe ARDS Severe case severe cases severe COVID-19 syndrome the SARS-CoV-2 Tidal volume Treatment variant Volume [DOI] 10.3346/jkms.2022.37.e82 PMC 바로가기 [Article Type] Case Reports
Result of one-year, prospective follow-up of intensive care unit survivors after SARS-CoV-2 pneumoniaResearch Published on 2022-03-092022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] acute respiratory distress syndrome ARDS changed Chest computed tomography clinical cohort of patient Complication CT scan defined deteriorate evaluate Follow-up functional Hospital stay ICU impairment intensive care interquartile range Lung injury male material median median age Most patient Multiorgan dysfunction normalized onset of symptoms participated Patient physical Physical examination Pneumonia Point primary endpoint profile proportion pulmonary Pulmonary function testing Pulmonary functional outcomes Quality of life questionnaire Result resulting risk SARS-CoV-2 SARS-CoV-2 pneumonia severe SARS-CoV-2 single-center supplementary material survived survivor symptom onset Symptoms Trial Trial registration were assessed [DOI] 10.1186/s13613-022-00997-8 PMC 바로가기 [Article Type] Research
Reduced levels of pulmonary surfactant in COVID-19 ARDSArticle Published on 2022-03-082022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 진단, [키워드] adult COVID-19 patients ARDS Biomarkers Bronchoalveolar lavage fluid clinical trial collected COVID-19 COVID-19 patient COVID-19 patients DPPC healthy control healthy controls infrared intubation less Medical research Pathogenesis Patient patient group principal component analysis Spectroscopy subgroups [DOI] 10.1038/s41598-022-07944-4 PMC 바로가기 [Article Type] Article
How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment혈액의 타고난 면역 체계가 COVID-19 유발 ARDS의 전신 병리에 기여하고 치료를 위한 잠재적인 표적을 제공하는 방법Review Published on 2022-03-082022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] Activation Acute kidney injury acute respiratory distress acute respiratory distress syndrome AMY-101 Angiogenesis apoptotic cells ARDS Biomarker bradykinin candidate drug candidate drugs cascade cascade system characterized chemokines Coagulation Coagulation system complement Complement inhibitor complement inhibitors Compound COVID-19 Crosstalk cytokine Cytokines damaged demonstrated dysregulation ecallantide eculizumab Evidence favor ground glass opacities heparin High dose high risk Icatibant IL-6 IL-6 levels in some incidence include Influenza influenza-like symptom Influenza-like symptoms inhibitor initiated Innate innate immune system intensive care treatment Kallikrein lanadelumab lead leukocytes life-threatening LMWH Lung injury mechanical ventilation mechanism moderate MOST oxygen oxygen saturation pandemic pathophysiology Patient patients Phase I plasma plasma proteins Platelets Potential predict Prevent Prognostic value pulmonary damage pulmonary inflammation receptor reduced Regulation respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-CoV-2 infected patient severity Support survival syndrome System systemic target the disease therapeutic option therapeutic options Thromboembolism thrombosis thrombotic Thrombotic complications translated Treatment treatment of COVID-19 Trial Usage Vascular ventilator virus [DOI] 10.3389/fimmu.2022.840137 PMC 바로가기 [Article Type] Review
Harnessing the Natural Toxic Metabolites in COVID-19Review Article Published on 2022-03-072022-10-31 Journal: Evidence-based Complementary and Alternative Medicine : eCAM [Category] COVID-19, [키워드] ACE2 receptor acute respiratory distress ARDS caused Cell China city cough COVID-19 COVID-19 disease COVID-19 symptoms diarrhoea disease Dry Effect evaluated fatigue Fever headache lung natural Novel coronavirus Pain pathophysiology pharmacological SARS-CoV-2 sore throat syndrome toxic toxins Transmission Treatment Wuhan [DOI] 10.1155/2022/3954944 PMC 바로가기 [Article Type] Review Article
Limitations of the ARDS criteria during high-flow oxygen or non-invasive ventilation: evidence from critically ill COVID-19 patientsObservational Study Published on 2022-03-072022-10-04 Journal: Critical Care [Category] MERS, SARS, 임상, [키워드] acute respiratory distress acute respiratory distress syndrome Analysis ARDS Berlin caused change COVID-19 patient criteria Critically ill Critically ill patient Evidence HFNC High-flow oxygen Hypothesis Hypoxemia ICU increase in increasingly indicate inspired oxygen fraction intensive care Invasive mechanical ventilation investigated limitation mechanical ventilation median Mild moderate nasal NIV Non-invasive Non-invasive respiratory support non-invasive ventilation oxygen pandemic PaO Patient prospective observational study provided pulmonary damage Respiratory failure Respiratory function Respiratory Support Result SARS-CoV2 severity single-center Steady state switching syndrome Uppsala University Variation ventilated patient was recorded with COVID-19 [DOI] 10.1186/s13054-022-03933-1 PMC 바로가기 [Article Type] Observational Study
Survival benefit of extracorporeal membrane oxygenation in severe COVID-19: a multi-centre-matched cohort studyArticle Published on 2022-03-032023-06-16 Journal: Intensive care medicine [Category] Fulltext, MERS, [키워드] ARDS COVID-19 ECMO severe respiratory failure [DOI] 10.1007/s00134-022-06645-w PMC 바로가기