ACE2 in the Gut: The Center of the 2019-nCoV Infected PathologyMolecular Biosciences Published on 2021-09-212022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] 2019-nCoV ACE2 angiotensin-converting enzyme 2 biological actions blood pressure caused center contagious coronavirus Diagnosis disorder function gastrointestinal tract Gut host cells indication Lungs pharmacological physiological functions Pneumonia Symptom The 2019-nCoV [DOI] 10.3389/fmolb.2021.708336 PMC 바로가기 [Article Type] Molecular Biosciences
Construction of a Recombinant Porcine Epidemic Diarrhea Virus Encoding Nanoluciferase for High-Throughput Screening of Natural Antiviral ProductsArticle Published on 2021-09-182022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] antioxidant antioxidants Antiviral compounds approved drug caffeic acid Cell clone Compound compounds construction contagious disease dose-dependent manner encoding epidemic diarrhea exhibited expected expressing expression Frame full-length cDNA genetics growth High-throughput screening identify in vitro Infection inhibit lithocholic acid luciferase activity morphology nanoluciferase natural Neonatal nLuc ORF3 oxygen PEDV platform positive correlation predominant produced product recombinant reduce replaced Replication Reverse genetics system screened Screening significantly therapeutic compound turn viral genome virus wild-type [DOI] 10.3390/v13091866 PMC 바로가기 [Article Type] Article
Influence of Population Density for COVID-19 Spread in Malaysia: An Ecological StudyBrief Report Published on 2021-09-182022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] 95% CI Analysis Cluster Clusters Community conducted contagious correlation COVID-19 COVID-19 case COVID-19 incidence COVID-19 infection density determine disease ecological Effect greater hotspot Infectious disease influence Linear regression model lockdowns Malaysia observé pandemic performed Population population density proportion Region Spread spread of COVID-19 Transmission Transmission model urbanization was used [DOI] 10.3390/ijerph18189866 PMC 바로가기 [Article Type] Brief Report
SARS-COV-2 Infection in Children and Red Blood Cell Distribution WidthPediatrics Published on 2021-09-092022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Adults adverse outcome association Blood categories cause Cell children clinical outcomes clinically contagious COVID-19 COVID-19 infection covid-19 outcome predictor COVID‐19 cycle threshold delta variant described distribution Emergency erythrocyte indices explain Hospitalization hypothese illnesses incidence infected children Infection Inflammatory MIS-C Multiple Patient pediatric pediatrics emergency positive prognostic Prognostic factor prognostic role Red red blood cell distribution width (RDW) required sars-cov-2 in children Severity of disease shown significant difference syndrome tested Viral load width [DOI] 10.7759/cureus.17837 PMC 바로가기 [Article Type] Pediatrics
Application of the amplification-free SERS-based CRISPR/Cas12a platform in the identification of SARS-CoV-2 from clinical samplesResearch Published on 2021-09-082022-10-29 Journal: Journal of Nanobiotechnology [Category] COVID-19, SARS, [키워드] amplification application biosensors Cas12a clinical sample contagious COVID-19 CRISPR described diagnostic disease identify nasopharyngeal swab specimen nucleic acid nucleic acids performed platform POCT point of care polymerase chain Quantitative rapid diagnostic assay reverse transcription RNA RNA extract RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA sensitivity Sensitivity and specificity Sliver nanoparticle supplementary material Surface-enhanced Raman scattering [DOI] 10.1186/s12951-021-01021-0 PMC 바로가기 [Article Type] Research
Dynamics of SARS-CoV-2 mutations reveals regional-specificity and similar trends of N501 and high-frequency mutation N501Y in different levels of control measuresSARS-CoV-2 돌연변이의 역학은 다양한 수준의 통제 조치에서 N501 및 고주파 돌연변이 N501Y의 지역 특이성과 유사한 경향을 나타냅니다Article Published on 2021-09-072022-09-10 Journal: Scientific Reports [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptation calculate caused characterized classification combinations contagious contagious disease coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 case COVID-19 cases death disease Dynamics effective evaluate the effect Evolution Frequency Genome Intervention measure molecular evolution Mutation mutations N501Y N501Y mutation normalization NPIs pandemic Prevalence Region regions relative frequency Reproduction number respiratory reveal SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 mutations sequenced severe acute respiratory syndrome Coronavirus Spread temporal dynamics Viral viral adaptation Viral genetics virus Virus evolution [DOI] 10.1038/s41598-021-97267-7 PMC 바로가기 [Article Type] Article
COVID-19 Pandemic Outbreak in the Subcontinent: A Data Driven AnalysisArticle Published on 2021-09-072022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] acute respiratory syndrome affected Analysis antagonistic Bayesian cause China Community contagious coronavirus COVID-19 COVID-19 pandemic Critical disease effective epidemiological data example Experimental result greater growth Human India indicate Infection likelihood modelling infectious disease New coronavirus Numerous observé predict Prevent produced Reproduction number reproduction numbers Research Responding SARS-CoV-2 severity of COVID-19 Spread spread of COVID-19 susceptible virus Wuhan [DOI] 10.3390/jpm11090889 PMC 바로가기 [Article Type] Article
Fast, accurate, point-of-care COVID-19 pandemic diagnosis enabled through advanced lab-on-chip optical biosensors: Opportunities and challengesReviews Published on 2021-09-072022-10-28 Journal: Applied Physics Reviews [Category] COVID-19, [키워드] acute respiratory syndrome approach asymptotic common Concentration contagious coronavirus COVID-19 COVID-19 pandemic detect Diagnosis diagnostic drastic effective examined include Influenza investigated measure MERS Middle East nasal noninvasive opportunity optical pandemic platform POC point-of-care reduce Saliva SARS-CoV-2 SARS-CoV-2 spike protein sensitivity serological samples Spread Symptom management syndrome Urine vaccination viral infection Viral load virion [DOI] 10.1063/5.0022211 PMC 바로가기 [Article Type] Reviews
Knowledge, awareness and practices of Pakistani professionals amid-COVID-19 outbreakClinical Trial Published on 2021-09-022022-10-04 Journal: Scientific Reports [Category] SARS, 임상, [키워드] addressed caused China contagious coronavirus country COVID-19 curative disease effective End evaluate Health care healthcare include indicated individual Infection information Italy Keeping measure media medication Microbiology Molecular biology outbreak pandemic performed persistence preventive measures professional professionals question questionnaire recorded response responses against Self-isolation Spain Spread spread to SPSS software susceptible the disease the SARS-CoV-2 Vaccine virus WHO World Health Organization [DOI] 10.1038/s41598-021-96705-w PMC 바로가기 [Article Type] Clinical Trial
Relaxing restrictions at the pace of vaccination increases freedom and guards against further COVID-19 waves예방 접종 속도에 따라 편안한 제한은 자유를 증가시킵니다.Research Article Published on 2021-09-022022-09-10 Journal: PLoS Computational Biology [Category] 변종, [키워드] addition age analyzed approach average average age benefit children compartmental model Contact Contagion contagious country COVID-19 COVID-19 pandemic COVID-19 vaccination curated death Deceased decrease demographics determine driver Drivers epidemiological European events example Face masks facilitate Factor FIVE Healthcare systems high mortality highlight hygiene ICU ICU patient ICU Patients immune responses Immunity Impact increase increase in Infection Intervention Keeping lifted Local maintain mass vaccination Mild moderate morbidity Mortality observé offer pace Post-infection Prevent preventive measure preventive measures quantified Quantitative reduce reduce mortality reducing reduction reduction in selected Seroprevalence significantly speed Strategy summer susceptibility susceptible Taking union vaccination Vaccinations Vaccine variants Viral viral spread virus variant [DOI] 10.1371/journal.pcbi.1009288 PMC 바로가기 [Article Type] Research Article