Predictors of infection, symptoms development, and mortality in people with SARS-CoV-2 living in retirement nursing homes은퇴 요양원에 거주하는 SARS-CoV-2 감염자의 감염, 증상 발생 및 사망률 예측인자Research Article Published on 2021-03-162022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] age Analysis Angiotensin II blocker chi-square test chronic chronic obstructive pulmonary disease Clinical data collected conducted correlated Cox proportional-hazards model death deaths dependent variable develop died Dyspnea enrolled evaluate evidenced Factor Fever foci Gender heparin high mortality hypokinetic disease increased risk Infection lower mortality risk lower risk male malignancies management Mental Disorders Mortality multivariate analyses Multivariate analysis neurological nursing homes Obstructive obstructive pulmonary disease pandemic Pearson Pearson chi-square test predictor predictors pulmonary disease receptor Retrospective study risk SARS-CoV-2 SARS-COV-2 infection Significant Spread Student’s t-test subjects Swab Symptom Symptoms syndrome Treatment variable was used with infection [DOI] 10.1371/journal.pone.0248009 PMC 바로가기 [Article Type] Research Article
A Retrospective Study Assessing the Effect of Diabetes on Mortality in Patients With COVID-19 at a Teaching Hospital in the United KingdomEndocrinology/Diabetes/Metabolism Published on 2021-03-152022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Admission adverse outcome age Assessing Characteristics Clinical characteristics Cohort Coronavirus disease 2019 COVID-19 COVID-19 diagnosis demonstrated diabete diabetes Diabetes Mellitus died Effect evaluated hospital increased mortality Inpatient intensive care Laboratory laboratory-confirmed male mechanical ventilation median age Mortality Multivariate analysis NHS no difference outcome over Patient patients with diabete performed Result Retrospective study Seven significantly increased subgroup analysis Teaching the patient Trust United Kingdom university variable [DOI] 10.7759/cureus.13902 PMC 바로가기 [Article Type] Endocrinology/Diabetes/Metabolism
Effectiveness of glucocorticoids in patients hospitalized for severe SARS-CoV-2 pneumoniaObservational Study Published on 2021-03-122022-10-05 Journal: Medicina clínica [Category] 임상, [키워드] acute respiratory syndrome Admission association Comparative coronavirus Coronavirus 2019 Coronavirus infection disease 2019 (COVID-19) Corticoïdes Corticosteroids Cytokine storm death disease dose Enfermedad por coronavirus 2019 (COVID-19) enrolled Evolution glucocorticoid greater Hospitalization ICU ICU admission include Índice de propensión. Infection intensive care unit less Logistic regression Mortality Multivariate analysis occur Patient patients hospitalized Pneumonia Prednisone Propensity index pulse regimen reported severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severe COVID-19 severe SARS-CoV-2 Síndrome agudo respiratorio severo por coronavirus 2 (SARS-CoV-2) three group treated Treatment was performed [DOI] 10.1016/j.medcli.2020.11.004 PMC 바로가기 [Article Type] Observational Study
Transmission Dynamics of SARS-CoV-2 during an Outbreak in a Roma Community in Thessaly, Greece—Control Measures and Lessons Learned그리스 테살리아의 로마 커뮤니티에서 발생한 SARS-CoV-2의 전파 역학—통제 조치 및 교훈Article Published on 2021-03-112022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age analyses Analysis analyzed asymptomatic transmission attack rates chi-square tests Community Contact tracing control measures coronavirus correlated COVID-19 COVID-19 outbreak COVID-19 symptom COVID-19 symptoms Ct values cycle cycle threshold death declined decrease designation disease spread Dynamics Effectiveness evaluate examined Factor Fisher’s exact test Fisher’s exact tests Greece hospital Hospitalization household household size household transmission identify increased risk index case index cases individual Infection Isolation lesson Logistic regression Logistic regression analyses measure mitigate Multivariate analysis occurred Oropharyngeal oropharyngeal samples outbreak Population screening respiratory risk Risk factors risk of infection RT-PCR SAR SARS-CoV-2 secondary attack rate severe acute respiratory syndrome Coronavirus Spread symptomatic case symptomatic cases tested threshold Transmission Univariate analysis Vulnerable populations was used were recorded with COVID-19 [DOI] 10.3390/ijerph18062878 PMC 바로가기 [Article Type] Article
Antibodies to SARS-CoV-2 and risk of past or future sick leaveSARS-CoV-2에 대한 항체 및 과거 또는 미래의 병가 위험Article Published on 2021-03-042022-09-01 Journal: Scientific Reports [Category] SARS, 진단, [키워드] adjusted odds ratio age antibody confidence interval disease Epidemiology healthy hospital Infection Infectious diseases Karolinska University Hospital Measures Multivariate analysis past Planning Population screening PROTECT Registered risk SARS-CoV-2 SARS-CoV-2 antibodies serum antibody sick subject Trial registration Viral viral antibodies viral antibody [DOI] 10.1038/s41598-021-84356-w PMC 바로가기 [Article Type] Article
MR-proADM as prognostic factor of outcome in COVID-19 patientsCOVID-19 환자에서 예후 인자로서의 MR-proADMArticle Published on 2021-03-042022-09-10 Journal: Scientific Reports [Category] 바이오마커, 치료기술, 치료법, [키워드] Admission affected Analysis assist association AUROC avoidance Bacteria Biomarker clinical clinical assessment clinical phenotype collected Complete COVID-19 patient COVID-19 patients cytokine Cytokines data set death demographic develop disease severity Escalation fungi Hospital admission IL-1B IL-6 IL-8 Inclusion Infectious diseases Inflammatory cytokines intubation Italy MR-proADM Multivariate analysis neutrophil neutrophil count Odds ratio Organ failure orotracheal intubation outcome Pathogenesis Patient Pneumonia Pragmatic Prognosis Prognostic factor Regional Retrospective analysis SARS-CoV-2 SARS-CoV-2 pneumonia scoring system sensitivity Sepsis Septic shock severe disease severity of COVID-19 significantly SOFA score specificity Therapies TNF-α Triaging trials university viruses was performed were measured WHO [DOI] 10.1038/s41598-021-84478-1 PMC 바로가기 [Article Type] Article
Impact of Arterial Stiffness on All-Cause Mortality in Patients Hospitalized With COVID-19 in SpainObservational Study Published on 2021-03-032022-10-05 Journal: Hypertension (Dallas, Tex. : 1979) [Category] SARS, 임상, [키워드] adjusted odds ratio Admission age all-cause mortality analyzed Antihypertensive treatment arterial Arterial stiffness association Blood blood pressure cardiovascular comorbidity Charlson Comorbidity Index Clinical characteristics coronavirus disease COVID-19 defined determinant diastolic died heart failure Hospitalization hypertension Impact In-hospital in-hospital mortality independent males multicenter cohort study Multivariate analysis network nonsurvivors Older Patient patients with COVID-19 predicted Prognostic value pulse pulse pressure. retrospective risk factor Sex significantly Spain Spanish stiffness subject survivor Systolic blood pressure women [DOI] 10.1161/HYPERTENSIONAHA.120.16563 PMC 바로가기 [Article Type] Observational Study
Comparing ICU admission rates of mild/moderate COVID-19 patients treated with hydroxychloroquine, favipiravir, and hydroxychloroquine plus favipiravir하이드록시클로로퀸, 파비피라비르, 하이드록시클로로퀸과 파비피라비르를 병용한 경증/중등도 COVID-19 환자의 ICU 입원률 비교Observational Study Published on 2021-03-012022-09-11 Journal: Journal of infection and public health [Category] 임상, 치료제, [키워드] adjusted Admission age Analysis applied approach city clinics Combination conducted covariate COVID-19 COVID-19 patient diagnosis of COVID-19 disease effect of treatment effect size eligible Favipiravir group HCQ Hospitalized Hydroxychloroquine ICU ICU admission ICU admission rate indicated intensive care intensive care unit Laboratory median age Mild Mild disease mild to moderate Moderate COVID-19 Multivariate analysis no statistically significant difference observational study Patient patients patients hospitalized Pneumonia Probability Propensity score propensity scores ranged reduced risk retrospective sensitivity analysis significantly higher statistically statistically significant difference study period the patient treated Treatment treatment group variable was used Weighting [DOI] 10.1016/j.jiph.2020.12.017 PMC 바로가기 [Article Type] Observational Study
Combination therapy of IFNβ1 with lopinavir-ritonavir, increases oxygenation, survival and discharging of sever COVID-19 infected inpatientsIFNβ1과 로피나비르-리토나비르의 병용 요법은 중증 COVID-19 감염 환자의 산소 공급, 생존 및 퇴원을 증가시킵니다.Article Published on 2021-03-012022-09-11 Journal: International immunopharmacology [Category] 치료제, [키워드] age all-cause mortality Analysis antiviral effects caused clinical study Combination Comorbidity conducted control group coronavirus COVID-19 COVID-19 patient COVID-19 patients COVID-19 treatment death rate defined determine dose during treatment Efficacy hospital hospitalized patient IFN-β1-a immunomodulatory in vitro activity in vivo increase infection with SARS-CoV-2 inflammatory cells inhibit Inpatient intensive care interferon interferon beta Interferon beta-1a International Lopinavir Lopinavir-ritonavir Lopinavir/ritonavir mediator Mortality Multivariate analysis Noninvasive ventilation outcome Oxygenation patients died receiving remained required Retrospective study risk of death Ritonavir SARS-CoV-2 Sex shown significantly standard care survival the disease therapy Treatment virus was done [DOI] 10.1016/j.intimp.2020.107329 PMC 바로가기 [Article Type] Article
The clinical course and prognostic factors of severe COVID-19 in Wuhan, China: A retrospective case-control study중국 우한에서 발생한 중증 코로나19의 임상경과 및 예후인자: 후향적 증례대조 연구Observational Study Published on 2021-02-262022-09-11 Journal: Medicine [Category] 임상, 치료기술, [키워드] 95%CI Analysis baseline BNP C-reactive protein C-reactive protein (CRP case-control study Clinical course conditions coronavirus disease Coronavirus disease 2019 COVID-19 CRP death diagnosed diagnosed with COVID-19 Disease progression Early detection identity independent predictor independent predictors independent risk factor independent risk factors Inpatient Lactate lactate dehydrogenase LDH lymphocyte Multivariate analysis neutrophil Neutrophil-to-lymphocyte ratio NLR peptide prognostic Prognostic factor Prognostic factors progression receiver operating characteristics retrospective Retrospective study Risk factors risk stratification ROC Severe case severe COVID-19 severe patients the disease was used were used Wuhan [DOI] 10.1097/MD.0000000000023996 PMC 바로가기 [Article Type] Observational Study