Tissue Proteomic Analysis Identifies Mechanisms and Stages of Immunopathology in Fatal COVID-19
조직 단백질 분석은 치명적인 covid-19에서 면역 병리학의 메커니즘과 단계를 식별합니다.
Original Research
Published on
Journal: American Journal of Respiratory Cell and Molecular [Category] COVID19(2023년), Fulltext, MERS, SARS, 유전자 메커니즘, 치료기술, 치료제,
Journal: American Journal of Respiratory Cell and Molecular [Category] COVID19(2023년), Fulltext, MERS, SARS, 유전자 메커니즘, 치료기술, 치료제,
[키워드] abundance
Activation
Analysis
Antiviral
antiviral responses
B-cell
Cancer
CD8A
chemotactic factor
Cluster
colony stimulating factor
component
Control tissue
coronavirus
coronavirus disease
correlated
COVID-19
CSF-1
DDX58
death
Deceased
disease stages
Donor
Evidence
Factor
fatal COVID-19
Host
IL-18
illness duration
immunoassay
immunopathology
Inflammation
lung
lymphocyte
Macrophage
macrophages
MCP-3
Meta-analysis
Monocytes
monocytes/macrophage
Mortality
multiplex
occur
organ
Organ Donors
OSM
overlap
parenchymal
pathway
Patient
phenol
plasma
Plasma cells
postmortem examination
postmortem examinations
proapoptotic factor
proapoptotic factors
profiles
Protein
proteomic
proteomics
prothrombotic
provide
provided
pulmonary thrombosis
quantification
RAGE
receptor signaling
reduce
required
S100A12
severity
spleen
Stage
subset
therapeutic target
therapy
thrombosis
tissue
tissues
TRIM21
TYMP
Unsupervised clustering
Viral
Viral RNA
was obtained
were used
[DOI] 10.1165/rcmb.2021-0358OC PMC 바로가기 [Article Type] Original Research
[DOI] 10.1165/rcmb.2021-0358OC PMC 바로가기 [Article Type] Original Research