Clinical characteristics and laboratory biomarkers changes in COVID-19 patients requiring or not intensive or sub-intensive care: a comparative study집중치료 또는 준집중치료가 필요한 코로나19 환자의 임상적 특성 및 실험실 바이오마커 변화: 비교 연구Observational Study Published on 2020-12-092022-09-10 Journal: BMC Infectious Diseases [Category] MERS, SARS, 바이오마커, 임상, [키워드] Admission aspartate benefit C-Reactive-Protein Care changes in Characteristics chest X-ray clinical Clinical characteristics clinical picture collected Comorbidities Composite COVID-19 COVID-19 patient COVID-19 patients defined demographic description develop diabete diabetes disease disease severity dry cough Factor Fatality rate Follow-up group had more Hospitalization hypertension ICU identifying include Infectious disease Infectious diseases inflammation marker Intensive intensive care Laboratory laboratory biomarker laboratory findings male median age neutrophil neutrophil count Novel coronavirus observation offer outcome pathological finding pathological findings Patient Pneumonia predisposing factors presence of comorbidity Primary outcome radiological Result Retrospective study risk factor Risk factors SARS-CoV-2 significantly higher Sub-intensive care supplementary material supportive care Swab swabs transaminase transfer transferred Treatment two groups unit worsening [DOI] 10.1186/s12879-020-05647-7 PMC 바로가기 [Article Type] Observational Study
Safely reducing haemodialysis frequency during the COVID-19 pandemicResearch Article Published on 2020-12-072022-10-28 Journal: BMC Nephrology [Category] COVID-19, MERS, SARS, [키워드] approach Biochemistry change Compliance coronavirus COVID 19 COVID-19 COVID-19 pandemic COVID-19 transmission death dialysis fluid overload Frequency Haemodialysis help higher risk hospitalised increases in indication mitigate Mortality outcome Patient patients per protocol Potassium protocol receiving reduced reducing renal Result Safe SARS-CoV-2 SBP selected serum short term sodium statistically significant Systolic blood pressure transfer transferred Transmission treated twice weekly were recorded [DOI] 10.1186/s12882-020-02172-2 PMC 바로가기 [Article Type] Research Article
Inflammatory cytokine depletion in severe coronavirus disease 2019 infectious pneumonia A case report중증 코로나바이러스 감염증 2019 감염성 폐렴에서 염증성 사이토카인 고갈 증례보고Case Reports Published on 2020-12-042022-09-12 Journal: Medicine [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome addition Administered Blood blood gas blood pressure branch Care Case report chest imaging Clinical features clinical manifestation convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 crisis cytokine diagnoses double filtration plasma pheresis dysfunction Fever filtration healthy heart rate high fever homeostatic Inflammatory cytokine inflammatory cytokine depletion Injury intravenous Isolation male maternity non-ICU nonproductive cough oropharyngeal swab parameter Patient patients PCR assay plasma Pneumonia positive reduce mortality referred to Research RT-PCR assay Safe severe acute respiratory syndrome Coronavirus severe coronavirus disease severe COVID-19 specimen SpO2 spontaneous respiration standard supportive care supportive care the patient therapy Tocilizumab transferred Travel Viral pneumonia [DOI] 10.1097/MD.0000000000023449 PMC 바로가기 [Article Type] Case Reports
Teamwork, communication and exchange despite Covid-19 – experiences from a digital elective in human medicine studies as part of the HiGHmed projectArticle Published on 2020-12-032022-11-01 Journal: GMS Journal for Medical Education [Category] Coronavirus, MERS, SARS, [키워드] accompanied acquisition activity carried Course courses data literacy digital teaching digitization of medicine Effect Future Intensive lack Medical informatics Medical studies offer offered offers pandemic promote social interaction stimulate Teamwork transferred [DOI] 10.3205/zma001379 PMC 바로가기 [Article Type] Article
The digital use of simulated patients in times of the corona pandemic – considerations and proposalsArticle Published on 2020-12-032022-11-01 Journal: GMS Journal for Medical Education [Category] Coronavirus, MERS, SARS, [키워드] approach aspect change changed Compliance condition conditions connection constructive alignment COVID 19 education FIVE human simulation Infection prevention Last learning objectives pandemic participant Participants Patient physical question Safety SARS-CoV-2 simulated patient Society Stress Topic transferred [DOI] 10.3205/zma001386 PMC 바로가기 [Article Type] Article
Decreased complement C3 levels are associated with poor prognosis in patients with COVID-19: A retrospective cohort study보체 C3 수치 감소는 COVID-19 환자의 나쁜 예후와 관련이 있습니다: 후향적 코호트 연구Observational Study Published on 2020-12-012022-09-12 Journal: International immunopharmacology [Category] MERS, SARS, 임상, 진단, [키워드] Admission analyzed breath Chest complement Complement C3 Complement pathway coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Decreased died discharged effective enrolled Factors greater hospital humoral Humoral immune Humoral immunity IgA IgE IgG IgM immune Immunoglobulin In-hospital death incidence Inflammatory indicators inhibition leukocyte Lymphocyte subsets management multivariable logistic regression Multivariable regression non-survivor Older age Patient performed poor prognosis retrospective cohort study risk factor Risk factors significantly survival survival group Survivors therapeutic transferred [DOI] 10.1016/j.intimp.2020.107070 PMC 바로가기 [Article Type] Observational Study
In-Hospital Mortality and Prediction in an Urban U.S. Population With COVID-19Infectious Disease Published on 2020-11-302022-10-31 Journal: Cureus [Category] COVID-19, [키워드] age alanine aminotransferase Aspartate transaminase calculator Chronic kidney disease clinical factor Cohort Complete Coronavirus disease 2019 Course COVID-19 COVID-19 infection COVID-19 patient COVID-19 test criterion CT scan defined demographic factor determine discharged electronic medical record eligible excluded Factor globe identify in-hospital mortality information Laboratory Laboratory tests Mortality Nasopharyngeal swab Negative predictive value New observation operator or chest X-ray outcome pandemic Patient Platelet Population positive prediction radiologic risk Risk factors risk stratification Robert Sample size score calculator sensitivity specificity study period subset the disease The United States transferred university urban USA variable was performed were excluded while White blood cell wood [DOI] 10.7759/cureus.11786 PMC 바로가기 [Article Type] Infectious Disease
Clinical and radiographic characteristics, management and short-term outcomes of patients with COVID-19 in Wenzhou, ChinaResearch Article Published on 2020-11-132022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] Admission antiviral drugs Biochemistry C-reactive protein Characteristics Chest China clinical Clinical characteristics Clinical features Computerized tomography confirmed COVID-19 case Coronavirus disease 2019 cough COVID-19 COVID-19 patient demographics Department Diagnosis diarrhea discharged distress Dizziness epidemiological history Epidemiology examined Fever headache hospital Hospitalization Infectious disease Isolation Laboratory tests management muscular nucleic acid tests observation outcome outcomes Oxygen therapy Patient patients patients with COVID-19 Prognosis Radiographic Radiographic characteristics recruited Result routine test SARS-CoV-2 severe cases Shortness of breath sore throat Symptom transferred treated Treatment viral disease was performed Wuhan [DOI] 10.1186/s12879-020-05528-z PMC 바로가기 [Article Type] Research Article
Efficacy and safety of sofosbuvir/ ledipasvir in treatment of patients with COVID-19; A randomized clinical trialCOVID-19 환자 치료에서 소포스부비르/레디파스비르의 효능 및 안전성; 무작위 임상 시험Randomized Controlled Trial Published on 2020-11-102022-09-11 Journal: Acta bio-medica : Atenei Parmensis [Category] 임상, 치료제, [키워드] accelerated adverse effect adverse effects adverse event assigned Care clinical clinical response clinical trial clinical trials comparable control group Course COVID-19 diarrhea drug discontinuation Efficacy and safety event faster Gastrointestinal Gastrointestinal events group groups hospital Hospitalization ICU Mild mild to moderate Mild to moderate COVID-19 Moderate COVID-19 Mortality mortality rate Most patients nausea not different occurred Open-label Patient patients provided randomized clinical trial receive Sample size Side effect Standard of care time transferred Treatment treatment of COVID-19 vomiting vomiting and diarrhea were assessed [DOI] 10.23750/abm.v91i4.10877 PMC 바로가기 [Article Type] Randomized Controlled Trial
Coronavirus-Associated Coagulopathy: Lessons From SARS-CoV1 and MERS-CoV for the Current SARS-CoV2 PandemicInternal Medicine Published on 2020-11-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome appear assist chest imaging clinical condition Clinical course clinician Coagulopathies Consensus Conservative management coronavirus coronavirus disease COVID-19 COVID-19-associated coagulopathy current Cytokine storm discharged home Effects elevated endothelial evaluate female Fever form Hospital stay hypercoagulability Hypothyroidism incidence Inflammation Inflammatory marker initial initiated intra-alveolar intubation left upper lobe lesson low molecular weight main pulmonary artery management manuscript mechanical ventilation MERS-CoV Middle East multifactorial nasopharyngeal nonproductive cough Pathogenesis pathophysiology Patient patients PCR test pro-inflammatory state Prophylactic recommendation remained respiratory syndrome coronavirus risk SARS virus SARS-CoV2 SARS-CoV2 infection SARS-CoV2- Seven stroke suggested systemic anticoagulation the timing therapeutic anticoagulation thrombosis Thrombotic complications tomography transferred while worsened [DOI] 10.7759/cureus.11310 PMC 바로가기 [Article Type] Internal Medicine