Individual variation of the SARS‐CoV‐2 receptor ACE2 gene expression and regulation
Original Article
[키워드] ACE2
ACE2 binding
ACE2 expression
acute respiratory syndrome
age
all ethnic groups
Asian
binding site
cardiovascular diseases
contributing to
coronavirus
COVID‐19
COVID‐19
Data analysis
decrease
diabetic patient
East Asians
enzyme
eQTLs
Ethnic groups
expression
expression levels
fatality
female
females
Gene Expression
Genes
hormone receptor
host cell receptor
Human
individual variation
individuals
Inflammatory cytokine
loci
majority
male
mice
molecular
negative correlation
Older
pathogen
pathway
Patient
population level
Quantitative
receptor ACE2
reduced
regions
Regulation
Regulatory
SARS‐CoV‐2
SARS‐COV2
Sex
sex hormone
shown
significant decrease
significantly higher
T2D
tissue
transcription factor
Treatment
treatment strategy
upregulated
upregulation
viral infection
virus infection
[DOI] 10.1111/acel.13168 PMC 바로가기 [Article Type] Original Article
[DOI] 10.1111/acel.13168 PMC 바로가기 [Article Type] Original Article