clinical trial – Page 240 – Communicable Diseases Research

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

MERS-CoV 감염의 붉은털 원숭이 모델에서 예방 및 치료 렘데시비르(GS-5734) 치료

530

Published on 2020-03-242022-09-10
Journal: Proceedings of the National Academy of Sciences of [Category] MERS, SARS, 비임상,

[키워드] 2019-nCoV acute respiratory syndrome Administered animal model animals Antiviral Antiviral treatment antiviral treatments breath Case fatality rate caused clinical benefit clinical disease Clinical signs clinical trial clinical trials coronavirus Coronaviruses CoV infection damage effective Efficacy Fatality rate GS-5734 implementation in vitro inhibited initiated inoculation lung lung lesions Lungs MERS MERS coronavirus MERS-CoV MERS-CoV infection Middle East Middle East respiratory syndrome mouse model nCoV Novel coronavirus prevented Prophylactic provided reduced reduction in Remdesivir Replication respiratory Respiratory disease respiratory tissues rhesus rhesus macaque Severe acute respiratory syndrome severe respiratory disease severity Severity of disease shown Significance Support tested therapeutic therapy Treatment utility virus replication were infected Wuhan Wuhan, China
[DOI] 10.1073/pnas.1922083117 PMC 바로가기 [Article Type] 530

Potential Treatments for COVID-19; a Narrative Literature Review

Review Article

Published on 2020-03-212022-10-27
Journal: Archives of Academic Emergency Medicine [Category] COVID-19,

[키워드] case reports cause clinical trial coronavirus COVID-19 drug therapy literature narrative pandemic Pathogenesis pathway Potential proliferation review SARS-CoV-2 therapy Treatment Vaccine virus WHO World Health Organization
PMC 바로가기 [Article Type] Review Article

Clinical trials on drug repositioning for COVID-19 treatment

Brief Communication

Published on 2020-03-202022-10-28
Journal: Revista Panamericana de Salud Pública [Category] COVID-19,

[키워드] 2019-nCoV approved bevacizumab China Chloroquine clinical clinical trial clinical trials Clinical trials as topic coronavirus Coronavirus infection Coronavirus pneumonia COVID-19 database death disease distribution drug repositioning eligibility criteria ensaios clínicos como assunto ensayos clínicos como asunto facilitate Favipiravir genus Betacoronavirus human immunoglobulin humans Hydroxychloroquine Infecções por Coronavirus infecciones por coronavirus interferons Intervention less limitations mammals Medicine Medicines Methylprednisolone neumonía viral novel coronavirus disease novel coronavirus SARS-CoV-2 oseltamivir outbreak Pandemias Pandemics participant Patient performed Pneumonia viral Pneumonia, viral Remdesivir reported Reposicionamento de medicamentos Reposicionamiento de medicamentos retrieved Ritonavir RNA virus TCM Traditional Chinese medicine Treatment Trial viroses virosis Virus diseases WHO World Health Organization Wuhan
[DOI] 10.26633/RPSP.2020.40 PMC 바로가기 [Article Type] Brief Communication

Concurrent treatment with intratympanic dexamethasone improves facial nerve recovery in Ramsay Hunt syndrome

중이 내 덱사메타손과의 동시 치료는 램지 헌트 증후군에서 얼굴 신경 회복을 개선합니다.

Article

Published on 2020-03-152023-06-02
Journal: Journal of the neurological sciences [Category] 대상포진, 두창, 수두,

[키워드] antiviral therapy clinical trial Intratympanic injection Ramsay Hunt syndrome steroid therapy Systemic administration.
[DOI] 10.1016/j.jns.2020.116678

Concurrent treatment with intratympanic dexamethasone improves facial nerve recovery in Ramsay Hunt syndrome

Article

Published on 2020-03-152023-06-02
Journal: Journal of the neurological sciences [Category] 두창,

[키워드] antiviral therapy clinical trial Intratympanic injection Ramsay Hunt syndrome steroid therapy Systemic administration.
[DOI] 10.1016/j.jns.2020.116678

Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A

인간 T 및 B 세포 반응의 에피토프 매핑 및 세부 특이성: 새로운 후보 혈액 단계 말라리아 백신 P27A

Original Research

Published on 2020-03-102024-08-11
Journal: Frontiers in immunology [Category] 말라리아,

[키워드] adjuvant clinical trial immune response malaria P27A Plasmodium falciparum populations Vaccine
[DOI] 10.3389/fimmu.2020.00412 PMC 바로가기 [Article Type] Original Research

Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review

Review

Published on 2020-02-262022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

[키워드] 2019 novel coronavirus 2019-nCoV acute respiratory syndrome Antiviral Asia Beijing carried China clinical trial Cochrane Library Compound condition criteria database diagnostics drug combination effective Efficacy Evidence global health Google search identify in vitro Intervention item Laboratory management MERS-CoV Middle East novel Novel coronavirus outbreak Phase 1 point-of-care testing kit polymerase chain Potential protocol Rapid Reporting Research resource reverse transcription review RT-PCR RT-PCR kit SARS-CoV Serological assay supported tested Therapeutics treatments Vaccine vaccine candidate vaccine trial were used
[DOI] 10.3390/jcm9030623 PMC 바로가기 [Article Type] Review

Efficacy of Delafloxacin versus Moxifloxacin against Bacterial Respiratory Pathogens in Adults with Community-Acquired Bacterial Pneumonia (CABP): Microbiology Results from the Delafloxacin Phase 3 CABP Trial

델라플록사신과 모키플록사신의 성능: 지역사회 획득 세균성 폐렴(CABP) 성인에서 세균 호흡기 병원체에 대한 미생물학적 결과 - 델라플록사신 3상 CABP 시험

Article

Published on 2020-02-212024-07-31
Journal: Med Instrum [Category] 폐렴구균 감염증,

[키워드] clinical trial community-acquired bacterial pneumonia Delafloxacin Fluoroquinolone
[DOI] 10.1128/AAC.01949-19 PMC 바로가기

Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China

Opinion Article

Published on 2020-02-072022-10-31
Journal: F1000Research [Category] COVID-19, MERS, SARS,

[키워드] 2019-nCoV 2019-nCoV infection ACE2 ACE2-Fc acute respiratory distress angiotensin-converting enzyme 2 approaches biologic block breath build clinical trial compassionate use coronavirus current death develop domain effective therapy effort fused help helping immune system Immunity Immunoglobulin infected individuals infected patient Infection investigators lung mechanism of action monoclonal antibody Mutation Neutralizing neutralizing antibody Novel coronavirus outbreak pandemic pathophysiology Patient patients Prevent producing Protective Protein protein expression provided quarantine receptor recruit Research respiratory viral sequence therapy treat Treatment Vaccine viral escape viral RNA genome virus while Wuhan Wuhan, China
[DOI] 10.12688/f1000research.22211.2 PMC 바로가기 [Article Type] Opinion Article

Plasmodium falciparum pre-erythrocytic stage vaccine development

말라리아 원충 피발열성 예방접종 개발

Review

Published on 2020-02-032024-08-11
Journal: Malaria Journal [Category] 말라리아,

[키워드] clinical trial immune response malaria sporozoite Vaccine vaccine efficacy
[DOI] 10.1186/s12936-020-3141-z PMC 바로가기 [Article Type] Review