Impact of Porcine Epidemic Diarrhea on Performance of Growing PigsResearch Article Published on 2015-03-132022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] addition ADG average average daily gain cause contribute decrease disease effort epidemic diarrhea evaluate feed conversion ratio feed intake help Impact impair indicated Infection information Measures Mortality outbreak performance pig Production quantification retrospective cohort study significantly the disease virus was performed [DOI] 10.1371/journal.pone.0120532 PMC 바로가기 [Article Type] Research Article
Sparse evidence of MERS-CoV infection among animal workers living in Southern Saudi Arabia during 2012Short Articles Published on 2015-03-032022-10-30 Journal: Influenza and Other Respiratory Viruses [Category] Coronavirus, MERS, [키워드] antibody cause collected conducted Control Evidence examined human serum Kingdom of Saudi Arabia lentiviral MERS-CoV MERS-CoV infection Middle East neutralization neutralized pseudoparticle virus neutralization assays Respiratory illness respiratory syndrome coronavirus Saudi Arabia sera serological evidence Spike protein viral pathogen zoonotic transmission [DOI] 10.1111/irv.12287 PMC 바로가기 [Article Type] Short Articles
Investigating the introduction of porcine epidemic diarrhea virus into an Ohio swine operationCase Report Published on 2015-02-152022-10-28 Journal: BMC veterinary research [Category] Coronavirus, MERS, [키워드] addition affected cause caused collected component coronavirus country Critical disease effective effort epidemic diarrhea epidemiological Evidence Feed highlight initiated limit Measures Mortality naïve Neonatal outbreak PEDV pellet positive provided RT-PCR Spread spread to stages Surveillance swine tested the United State The United States Transmission Vaccine virus [DOI] 10.1186/s12917-015-0348-2 PMC 바로가기 [Article Type] Case Report
Successful recovery of MERS CoV pneumonia in a patient with acquired immunodeficiency syndrome: A case reportArticle Published on 2014-11-292022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, [키워드] Case report cause CMV, cytomegalovirus CoV CT, Computed tomography diagnosed East ELISA, enzyme linked immunosorbent assay HIV HIV patient HIV, Human immunodeficiency virus Human immunodeficiency interferon MERS MERS coronavirus MERS CoV, Middle East Respiratory Syndrome Coronavirus middle morbidity and mortality outcome Patient PJP, pneumocystis jirovecii pneumonia Pneumonia reported respiratory ribavirin RT-PCR, Reverse transcription polymerase chain reaction severe pneumonia severity shedding TMP/SX, trimethoprim/sulfamethoxazole Treatment were used with HIV [DOI] 10.1016/j.jcv.2014.11.030 PMC 바로가기 [Article Type] Article
A Thermolabile Aldolase A Mutant Causes Fever-Induced Recurrent Rhabdomyolysis without Hemolytic Anemia열불안정성 알돌라제 A 돌연변이는 용혈성 빈혈 없이 발열로 인한 재발성 횡문근 융해증을 유발합니다Research Article Published on 2014-11-132022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accumulated affected ALDOA Aldolase arginine arginine supplementation betaine cause chaperones Cytokines deficiency Deleterious Dexamethasone droplet erythrocytes Exacerbation expand febrile glycerol hemolytic hemolytic anemia high temperature homozygous mutation illnesses in vitro Lipid lipid droplets mechanism myoblast myoblasts Myoglobinuria Myopathy Patient Protein Recurrent reduced reported rescued rhabdomyolysis severe disease thermolability tissue specific Treatment triggered was increased [DOI] 10.1371/journal.pgen.1004711 PMC 바로가기 [Article Type] Research Article
The avian coronavirus spike proteinArticle Published on 2014-10-172022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Gammacoronavirus affecting Amino acid attachment protein avian coronavirus binding cause Cell Cell culture cells circulating contagious coronavirus disease effort focus Host IBV in vivo Infectious Bronchitis Virus Infectious bronchitis virus IBV Intervention organ other tissue Pathogenesis Protective reproductive respiratory tract S1 domain serotype spike Spike protein Spike proteins strain therapeutic tissue tissue tropism tissues tropism Variation virus [DOI] 10.1016/j.virusres.2014.10.009 PMC 바로가기 [Article Type] Article
Alterations in Nerve-Evoked Bladder Contractions in a Coronavirus-Induced Mouse Model of Multiple SclerosisResearch Article Published on 2014-10-132022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] agonist alteration ATP Bethanechol bladder bladder dysfunction bladder strips blocked cause changes in CNS Combination contractile contraction controls Demyelination disease EFS help male mice Model mouse mucosa Multiple multiple sclerosis muscarinic neurodegenerative not significantly different pathologic pathological change performed physiological receptor receptors reduced removal respond restored Result resulting sclerosis significantly significantly increased Symptom tension underlie urgency urinary frequency Urinary tract [DOI] 10.1371/journal.pone.0109314 PMC 바로가기 [Article Type] Research Article
Coronavirus-induced ER stress response and its involvement in regulation of coronavirus–host interactionsArticle Published on 2014-10-072022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] activated activating Activation anti-apoptotic Apoptosis Apoptotic cell death ATF6 autophagy cause Cell coronavirus Coronavirus infection coronavirus protein cross-talk Degradation disturbance Endoplasmic reticulum ER stress eukaryotic cells Evidence facilitate homeostasis induce infected cells innate immune response Innate immunity Interaction involved knowledge Modification modulate occur pathological conditions pathway Pathways physiological pro-apoptotic pro-inflammatory cytokines pro-inflammatory response Protein protein synthesis Regulation Replication shown signaling pathway signaling pathways transcriptional translation transmembrane unfolded protein response UPR [DOI] 10.1016/j.virusres.2014.09.016 PMC 바로가기 [Article Type] Article
Beclin 1 Is Required for Neuron Viability and Regulates Endosome Pathways via the UVRAG-VPS34 ComplexBeclin 1은 뉴런 생존에 필요하고 UVRAG-VPS34 복합체를 통해 엔도솜 경로를 조절합니다Research Article Published on 2014-10-022022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] activity addition animal model assembly autophagosome autophagy Beclin 1 Brain cause cell line cellular characterized Complete complex complexes conditions Coordinate deficiency disease Diseases Disruption distribution EEA1 endocytosis endosome Endosomes Evidence failure function Genetic human disease impair impairment implicated in addition to in vivo Infectious disease Interaction involved leads maintain mammalian maturation membrane molecular mechanism mutant neurodegeneration neurodegenerative Neuron neuronal neurons nucleation organelle overexpressed p40 pathway Pathways phosphatidylinositol phosphatidylinositol 3-kinase physiological PI3K Previous studies previous study Protein recent recruit recruitment regulate Regulation required rescued reveal RUBICON survival tumorigenesis UVRAG viability [DOI] 10.1371/journal.pgen.1004626 PMC 바로가기 [Article Type] Research Article
Infection with MERS-CoV Causes Lethal Pneumonia in the Common MarmosetResearch Article Published on 2014-08-212022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] addition Analysis animal model cause common Comorbidities comparable complicate demonstrated different time point Dipeptidyl peptidase 4 disease Disease model Efficacy evaluate expression Extensive humans immune inflammatory pathways Interaction intranasal lack lesion lethal lung marmoset marmoset model MERS-CoV MERS-CoV infection Middle East Mild modeling moderate disease MOST ocular Pathogenesis post inoculation potential therapeutic agent predicted Protein receptor required respiratory syndrome coronavirus rhesus RNAseq robust severe disease severe pneumonia severity spike glycoprotein the disease translated treated treatment strategy Vaccine Viral load virus entry was tested while [DOI] 10.1371/journal.ppat.1004250 PMC 바로가기 [Article Type] Research Article