Characteristic of COVID-19 infection in pediatric patients: early findings from two Italian Pediatric Research NetworksShort Communication Published on 2020-06-032022-10-31 Journal: European journal of pediatrics [Category] COVID-19, MERS, SARS, [키워드] 95% CI adolescents Asymptomatic case sery Characteristics children children with COVID-19 Chronic diseases clinical presentation Comorbidities COVID-19 COVID-19 infection Critical Critical disease diagnosed disease enrolled Europe Evidence hospital Hospitalized hospitals Infant intensive care Italian Italy Mild moderate disease network nine outcome pandemic pediatric Population Region Respiratory Support risk risk factor selected severe cases severe disease severity significantly increased supplementary material treated with COVID-19 [DOI] 10.1007/s00431-020-03683-8 PMC 바로가기 [Article Type] Short Communication
Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO studyArticle Published on 2020-05-292022-11-01 Journal: Diabetologia [Category] COVID-19, MERS, [키워드] 95% CI acute respiratory syndrome Admission age Analysis AST blockers BMI C-reactive protein caused Characteristics Comorbidity Complication conducted Coronavirus-2 covariate COVID-19 COVID-19 patient COVID-19 severity death diabete diabetes Diabetic died discharged Dyspnoea Endpoint feature French Glucose HbA1c hospitalised hypertension independent predictor Infection Inpatient intubation life-threatening Lymphocyte count mechanical ventilation Median BMI men multicentre multivariable analysis multivariable logistic regression Obstructive Participants peer-reviewed performed phenotypic Primary outcome Prognosis Prognostic value RAAS remained reported Result risk of death SARS-CoV-2 Sex significantly supplementary material Therapies tracheal treated Treatment type 2 diabete Univariate analysis virus with COVID-19 [DOI] 10.1007/s00125-020-05180-x PMC 바로가기 [Article Type] Article
Impact of the COVID-19 pandemic on patients suffering from musculoskeletal tumoursOriginal Paper Published on 2020-05-262022-10-29 Journal: International Orthopaedics [Category] COVID-19, MERS, SARS, [키워드] cause caused Chemotherapy complications conducted coronavirus disease COVID-19 COVID-19 pandemic death European evaluate expected FIVE healthcare Impact infiltration life-threatening loss of function malignancy morbidity Musculoskeletal Musculoskeletal tumor Neurovascular oncology Pain pandemic Patient performed physician Physicians question Radiotherapy reduction in Result Sarcoma SARS-CoV-2 SARS-CoV-2 pandemic severe acute respiratory syndrome coronavirus 2 Society supplementary material surgical Treatment tumors tumour [DOI] 10.1007/s00264-020-04636-4 PMC 바로가기 [Article Type] Original Paper
Harnessing the power of novel animal-free test methods for the development of COVID-19 drugs and vaccinesGuest Editorial Published on 2020-05-232022-10-28 Journal: Archives of Toxicology [Category] COVID-19, MERS, SARS, [키워드] accelerated antibody approach approaches biological processe carcinogenicity country COVID-19 Critical drug Drug discovery Efficacy EMA epitope European Medicines Agency feature Health Laboratory limitation Molecular biology Organoid pandemic pathogen predict resource SARS-CoV2 supplementary material Vaccine virus virus infectivity [DOI] 10.1007/s00204-020-02787-2 PMC 바로가기 [Article Type] Guest Editorial
The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-19Article Published on 2020-05-232022-10-28 Journal: The protein journal [Category] COVID-19, SARS, [키워드] acute respiratory syndrome cause caused Coronavirus-2 COVID-19 death disease Effect global pandemic Protein Proteins respiratory SARS CoV-2 supplementary material virus [DOI] 10.1007/s10930-020-09901-4 PMC 바로가기 [Article Type] Article
Model based approach for estimating the dosage regimen of indomethacin a potential antiviral treatment of patients infected with SARS CoV-2SARS CoV-2에 감염된 환자의 잠재적인 항바이러스 치료 인도메타신의 투여 요법을 추정하기 위한 모델 기반 접근 방식Original Paper Published on 2020-05-202022-09-10 Journal: Journal of Pharmacokinetics and Pharmacodynamics [Category] MERS, SARS, 비임상, [키워드] administration anti-inflammatory drug antiviral activity antiviral property Antiviral treatment approach assumption benefit best breath canine Clinical dose Complete coronavirus criteria dosage dose dosing regimen dosing regimens drugs effective evaluated expected Human human SARS-CoV-2 identify In-vitro indomethacin Model Model-based Patient Prospective clinical trial regimen SARS CoV-2 SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 coronavirus SARS-CoV-2 pandemic shown supplementary material the SARS-CoV-2 therapeutic effect Translational model Treatment Viral Viral load [DOI] 10.1007/s10928-020-09690-4 PMC 바로가기 [Article Type] Original Paper
Dynamic interventions to control COVID-19 pandemic: a multivariate prediction modelling study comparing 16 worldwide countriesCovid-19 Published on 2020-05-192022-10-31 Journal: European Journal of Epidemiology [Category] COVID-19, MERS, SARS, [키워드] Admission Analysis basic reproduction number categories Combination Consequences coronavirus country COVID-19 COVID-19 pandemic Critical care death deaths defined develop disease dynamic Dynamic interventions effective efficient Epidemiology Frequency health system Hospitalization ICU Impact implementation Infection Infectious disease intensive care interval Intervention limits measure Measures National NPI NPIs outbreak pandemic Pragmatic Prediction modelling Prevent reduce reduced reduction Region Reproduction number social distancing supplementary material the mean trajectory Transmission while [DOI] 10.1007/s10654-020-00649-w PMC 바로가기 [Article Type] Covid-19
Burden and prevalence of prognostic factors for severe COVID-19 in SwedenCovid-19 Published on 2020-05-182022-10-31 Journal: European Journal of Epidemiology [Category] COVID-19, MERS, SARS, [키워드] age assumption Asthma burden Burden of disease calculated Cancer cardiovascular disease Care chronic obstructive Control COVID-19 Critical care diabete disease effort European Factor finding FIVE Health healthcare increased risk individual individuals Kalmar Local medical condition National pandemic Prevalence prevention Prognostic factor Prognostic factors pulmonary disease ranged resource severe COVID-19 study population supplementary material Support Swedish World Health Organization [DOI] 10.1007/s10654-020-00646-z PMC 바로가기 [Article Type] Covid-19
Rapid response in the COVID-19 pandemic: a Delphi study from the European Pediatric Dialysis Working GroupOriginal Article Published on 2020-05-172022-10-28 Journal: Pediatric Nephrology (Berlin, Germany) [Category] COVID-19, MERS, [키워드] Analysis analyzed approach Care changes in children Chronic kidney disease clinical care conducted COVID-19 COVID-19 pandemic DelPhi develop dialysis Europe European European country Evidence group Guidance Health care system health emergency information knowledge less Local management methodology pandemic pattern pediatric public health crisis Quantitative Rapid real time recommendations Regulation reported response Result specific patient group Spread supplementary material Transmission transplantation working [DOI] 10.1007/s00467-020-04584-6 PMC 바로가기 [Article Type] Original Article
Prevention and management of COVID-19 among patients with diabetes: an appraisal of the literatureReview Published on 2020-05-142022-11-01 Journal: Diabetologia [Category] COVID-19, MERS, SARS, [키워드] addition affected age antiviral therapy blood glucose Community Comorbidity complex interplay Complication coronavirus coronavirus disease COVID-19 COVID-19-related death Critical diabete diabetes disease disease spread Effect equipment glycaemic control Health healthcare immunomodulatory increased risk Inflammatory response Injury insulin investigated knowledge lockdown management measure medication Mild mild illness Most patient Optimising outcome pandemic Patient patients with diabete peer-reviewed predictor prevent disease spread prevention risk SARS-CoV-2 severe COVID-19 severe disease Strategy supplementary material therapy Treatment Vaccine with COVID-19 [DOI] 10.1007/s00125-020-05164-x PMC 바로가기 [Article Type] Review