clinical trial – Page 247 – Communicable Diseases Research

Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus

Online Report

Published on 2016-07-012022-10-31
Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS,

Progress and prospects for blood-stage malaria vaccines

혈액 단계 말라리아 백신의 진행 상황과 전망

Review

Published on 2016-06-022024-08-12
Journal: Expert review of vaccines [Category] 말라리아,

[키워드] blood-stage challenge models clinical trial in vitro assays malaria Plasmodium falciparum Vaccine
[DOI] 10.1586/14760584.2016.1141680 PMC 바로가기 [Article Type] Review

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure

심부전의 사망률과 관련된 염색체 5q22의 유전적 변이 발견

Research Article

Published on 2016-05-052022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] acting activate addition African allergic allergy applied approach assays association Asthma Blood Cell chemokine chemokines chromosome clinical trial clinical trials cytokine death dendritic cell dendritic cells determinant development DNA methylation ENhance enhancer region epigenomic Evidence evidence of expressing expression Factor failure Follow-up gene encode Genetic Genetic variant Genome-wide association studies Genome-wide association study genotyping heart heart failure HEK293 high mortality human cell human tissues identify increase increased risk independent induce inhibiting knockdown leads maintain Mast cells maturation Meta-analysis molecular Monocytes Mortality multiple tissues NHLH1 Patient performed polymorphism Population populations Positive selection predicted promote replicated reporter reporter gene responses risk allele subject T helper T-cell therapeutic Therapeutics Therapies transcription factor TSLP turn variant Whole blood
[DOI] 10.1371/journal.pgen.1006034 PMC 바로가기 [Article Type] Research Article

Preparing for future efficacy trials of severe malaria vaccines

Article

Published on 2016-04-072024-08-27
Journal: Vaccine [Category] 말라리아,

[키워드] clinical trial Immunity Sample size severe malaria Vaccine
[DOI] 10.1016/j.vaccine.2016.02.053

Daily consumption of ready-to-use peanut-based therapeutic food increased fat free mass, improved anemic status but has no impact on the zinc status of people living with HIV/AIDS: a randomized controlled trial

바로 사용할 수 있는 땅콩 기반 치료 식품을 매일 섭취하면 무지방 질량이 증가하고 빈혈 상태가 개선되지만 HIV/AIDS 감염자의 아연 상태에는 영향을 미치지 않습니다. 무작위 대조 시험

Research Article

Published on 2016-01-042022-08-09
Journal: BMC Public Health [Category] 임상,

[키워드] adjusted Admission affected AIDS Anemia anemic anemic status ART atomic absorption spectrometry Bio-Impedance Analysis Body body composition body fat body weight both groups clinical trial comparable Concentration conducted Control control group Controlled Controlled clinical trial CRP Daily daily recommended intake deficiency discharge energy fat Fat free mass fat-free mass food group hemoglobin HIV/AIDS Hospitalized Improving Individual dietary Infection iron Malnutrition measure muscle mass on admission patients percentage body fat plasma plasma zinc concentration PLWH positive Randomized controlled trial Randomly ready-to-use therapeutic food receive Recommended Dietary Allowances Registered remained Result Senegal severe malnutrition significantly standard hospital diet status sub-Saharan Africa the patient therapeutic Therapeutic food Treatment was determined was measured were measured Zinc zinc deficiency α1-AGP
[DOI] 10.1186/s12889-015-2639-8 PMC 바로가기 [Article Type] Research Article

Combination of Tenofovir Disoproxil Fumarate and Peginterferon α-2a Increases Loss of Hepatitis B Surface Antigen in Patients With Chronic Hepatitis B

Randomized Controlled Trial

Published on 2016-01-012023-06-18
Journal: Gastroenterology [Category] B형 간염,

[키워드] clinical trial HBeAg seroconversion HBV Virologic response
[DOI] 10.1053/j.gastro.2015.09.043 [Article Type] Randomized Controlled Trial

A phase 2, open-label, multicenter study of the long-term safety of siltuximab (an anti-interleukin-6 monoclonal antibody) in patients with multicentric Castleman disease

Clinical Research Paper

Published on 2015-10-062024-09-02
Journal: Oncotarget [Category] 대상포진,

[키워드] clinical trial interleukin-6 multi-centric Castleman's disease siltuximab
PMC 바로가기 [Article Type] Clinical Research Paper

Efficacy and safety of iota-carrageenan nasal spray versus placebo in early treatment of the common cold in adults: the ICICC trial

Research

Published on 2015-10-052023-08-29
Journal: Respiratory Research [Category] E형 간염,

[키워드] clinical trial common cold Human rhinovirus iota-carrageenan
[DOI] 10.1186/s12931-015-0281-8 PMC 바로가기 [Article Type] Research

Lipid lowering efficacy and safety of Ezetimibe combined with rosuvastatin compared with titrating rosuvastatin monotherapy in HIV-positive patients

HIV 양성 환자에서 로수바스타틴 적정 단독요법과 비교한 에제티미브와 로수바스타틴 병용요법의 지질강하 효능 및 안전성

Research

Published on 2015-06-192022-09-06
Journal: Lipids in Health and Disease [Category] Communicable Disease,

[키워드] addition AIP ALT Antiretroviral therapy API apoA1 ApoB Apolipoprotein B appear AST baseline characteristics C-reactive protein change Characteristics cholesterol clinical symptom Clinical symptoms clinical trial Combination combination treatment develop dose dyslipidemia dyslipidemias Efficacy Efficacy and safety eligible examined Ezetimibe group groups guideline HDL-C High-density lipoprotein High-density lipoprotein cholesterol High-sensitivity C-reactive protein HIV HIV-infected patient HIV-infected patients hsCRP improvement increase in LDL-C Lipid lipid profile Low-density lipoprotein Low-Density Lipoprotein cholesterol Mild minimum monotherapy myalgias not differ Open-label parameter Patient patients with HIV percentage plasma Primary outcome Randomized Result Rosuvastatin Safe Significant statin targets therapy Total cholesterol Transport treatment groups Trial Triglyceride two patients
[DOI] 10.1186/s12944-015-0054-x PMC 바로가기 [Article Type] Research

The case for a typhoid vaccine probe study and overview of design elements

장티푸스 백신 조사 연구의 필요성과 설계 요소 개요

journal-article

Published on 2015-06-012024-07-30
Journal: Vaccine [Category] 살모넬라증,

[키워드] clinical trial Disease burden Salmonella Typhi Trial design typhoid typhoid vaccine Vaccine Vaccine probe study.
[DOI] 10.1016/j.vaccine.2015.03.085 [Article Type] journal-article