Evaluation of safety and immunogenicity of HNVAC, an MDCK-based H1N1 pandemic influenza vaccine, in Phase I single centre and Phase II/III multi-centre, double-blind, randomized, placebo-controlled, parallel assignment studiesClinical Trial Published on 2014-07-312023-06-25 Journal: Vaccine [Category] 신종인플루엔자, [키워드] Cell culture clinical trial H1N1 Influenza pandemic Vaccine [DOI] 10.1016/j.vaccine.2014.05.039 [Article Type] Clinical Trial
Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study케냐에서 단순한 팔수리움 말라리아 성인을 대상으로 한 정맥 주사 아르테순산의 약리학적 평가: 2상 연구Research Published on 2014-07-222024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] artesunate clinical trial dihydroartemisinin intravenous pharmacokinetics Uncomplicated falciparum malaria [DOI] 10.1186/1475-2875-13-281 PMC 바로가기 [Article Type] Research
Phase I / II study of brentuximab vedotin in Japanese patients with relapsed or refractory CD30-positive Hodgkin’s lymphoma or systemic anaplastic large-cell lymphomaOriginal Article Published on 2014-07-012024-09-04 Journal: Cancer science [Category] 대상포진, [키워드] Anaplastic large cell lymphoma brentuximab vedotin clinical trial Hodgkin's lymphoma Japanese patients [DOI] 10.1111/cas.12435 PMC 바로가기 [Article Type] Original Article
The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird methodResearch Article Published on 2014-02-182023-08-28 Journal: BMC Medical Research Methodology [Category] E형 간염, [키워드] clinical trial Cochrane Database of Systematic Reviews heterogeneity Meta-analysis Random effects Trial size type I error [DOI] 10.1186/1471-2288-14-25 PMC 바로가기 [Article Type] Research Article
How experiences become data: the process of eliciting adverse event, medical history and concomitant medication reports in antimalarial and antiretroviral interaction trials경험이 데이터가 되는 방법: 항말라리아 및 항레트로바이러스 상호작용 시험에서 이상반응, 병력 및 병용 약물 보고서를 도출하는 과정Research Article Published on 2013-11-142024-07-27 Journal: BMC Medical Research Methodology [Category] 말라리아, [키워드] clinical trial Elicitation Harm HIV malaria pharmacovigilance Safety social context South Africa Tanzania [DOI] 10.1186/1471-2288-13-140 PMC 바로가기 [Article Type] Research Article
Herpes zoster vaccination in SLE: a pilot study of immunogenicitySLE에서 대상포진 예방접종: 면역원성의 실험 연구Clinical Trial Published on 2013-11-012023-05-31 Journal: The Journal of rheumatology [Category] 대상포진, 두창, 수두, 홍역, [키워드] clinical trial herpes zoster Infection systemic lupus erythematosus Vaccine Zostavax [DOI] 10.3899/jrheum.130170 PMC 바로가기 [Article Type] Clinical Trial
Herpes zoster vaccination in SLE: a pilot study of immunogenicityClinical Trial Published on 2013-11-012023-05-31 Journal: The Journal of rheumatology [Category] 두창, 수두, 홍역, [키워드] clinical trial herpes zoster Infection systemic lupus erythematosus Vaccine Zostavax [DOI] 10.3899/jrheum.130170 PMC 바로가기 [Article Type] Clinical Trial
Experience with monocomponent acellular pertussis combination vaccines for infants, children, adolescents and adults—A review of safety, immunogenicity, efficacy and effectiveness studies and 15 years of field experience모노컴포넌트 무세포 경련 결합 백신에 대한 영유아, 어린이, 청소년 및 성인의 경험 - 안전, 면역원성, 효능 및 효과성 연구 및 15년의 현장 경험 검토journal-article Published on 2013-10-012024-08-01 Journal: Vaccine [Category] 백일해, [키워드] aP vaccine. clinical trial Hydrogen peroxide inactivated pertussis toxoid Statens Serum Institut Whooping cough [DOI] 10.1016/j.vaccine.2013.08.034 [Article Type] journal-article
Comparison of modeling methods to determine liver-to-blood inocula and parasite multiplication rates during controlled human malaria infectionArticle Published on 2013-07-152024-08-28 Journal: Nanoscale [Category] 말라리아, [키워드] clinical trial malaria modeling Plasmodium falciparum qPCR Vaccine
Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases기능성 IL6R 358Ala 대립유전자는 전통적인 IL-6 수용체 신호 전달을 손상시키고 다양한 염증성 질환의 위험에 영향을 미칩니다Research Article Published on 2013-04-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 358Ala Abdominal aortic aneurysm affecting allele analyzed aortic aneurysm approach Arthritis Asp358Ala association Asthma Atrial fibrillation Author balance benefit Cambridge BioResource causal variant CD4+ T cell CD4+ T cells CHD Chronic diseases circulating cleavage clinical trial clinical trials common diseases complex complex diseases Concentration Control copy Coronary heart disease Critical cytokine diabete diabetes etiology Evidence expression functional Genetic genetic association Genetic variation heart disease human disease identify IL-6 IL-6 receptor IL-6 signaling IL-6R IL-6R signaling IL-6R signaling pathway IL6R Immune cell immune cells impairment implicated implication increase increase in independent Inflammatory Inflammatory responses influence interleukin interleukin-6 isoform mechanism membrane-bound molecular mechanism monocyte Monocytes mononuclear cell mononuclear cells Non-synonymous nucleotide Patient PBMCs Peripheral blood Peripheral blood mononuclear cells Phosphorylation polymorphism Population protein level protein levels RA reduce reduced reduction regulated Regulation rheumatoid arthritis risk rs2228145 Signaling sIL-6R single nucleotide Single nucleotide polymorphism soluble IL-6R Stat1 STAT3 Stimulation suggested surface expression surface receptor susceptibility T cells T1D therapeutic intervention therapy These data Transcription transcription factor transcription factors translate Treatment response Type 1 diabetes variant Variation Volunteer [DOI] 10.1371/journal.pgen.1003444 PMC 바로가기 [Article Type] Research Article