Selective inhibitors of Plasmodium falciparum glycogen synthase-3 (PfGSK-3): New antimalarial agents?article Published on 2015-10-312024-09-01 Journal: Cities [Category] 말라리아, [키워드] antimalarial Glycogen synthase kinase-3 inhibitor Paullone Plasmodium Thieno[2,3-b]pyridine [Article Type] article
Parasite clearance after malaria therapy: staying a step ahead of drug resistance말라리아 치료 후 기생충 제거: 약물 내성에 한 발 앞서 나가기Commentary Published on 2015-10-022024-08-13 Journal: BMC Medicine [Category] 말라리아, [키워드] antimalarial Artemisinin combination therapy Falciparum malaria Parasite clearance [DOI] 10.1186/s12916-015-0486-1 PMC 바로가기 [Article Type] Commentary
Use of bacterial surrogates as a tool to explore antimalarial drug interaction: Synergism between inhibitors of malarial dihydrofolate reductase and dihydropteroate synthasearticle Published on 2015-09-302024-09-01 Journal: Family process [Category] 말라리아, [키워드] antimalarial Bacterial surrogate Dihydrofolate reductase DIHYDROPTEROATE SYNTHASE Plasmodium falciparum synergism [Article Type] article
Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotypearticle Published on 2015-09-302024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] antimalarial Drug lead indole Reagent-based diversity [Article Type] article
Synthesis, Docking, In Vitro and In Vivo Antimalarial Activity of Hybrid 4-aminoquinoline-1,3,5-triazine Derivatives Against Wild and Mutant Malaria Parasitesarticle Published on 2015-09-302024-09-01 Journal: Chemical Biology & Drug Design [Category] 말라리아, [키워드] 1,3,5-triazine aminoquinoline antimalarial docking [Article Type] article
The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugsArticle Published on 2015-08-272024-08-29 Journal: International Journal for Parasitology: Drugs and Drug Resistance [Category] 말라리아, [키워드] antimalarial Cipargamin Drug discovery PfATP4 Plasmodium Resistance selection.
Bayesian models trained with HTS data for predicting β-haematin inhibition and in vitro antimalarial activityArticle Published on 2015-08-152024-08-29 Journal: Bioorganic & Medicinal Chemistry [Category] 말라리아, [키워드] antimalarial bayesian statistics Haemozoin in silico screening machine learning malaria β-haematin
Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agentsArticle Published on 2015-08-152024-08-29 Journal: Bioorganic & Medicinal Chemistry [Category] 말라리아, [키워드] antimalarial antiplasmodial Aspartic protease inhibitors Spiropiperidine hydantoins.
Development and validation of a bioanalytical method by LC-MS/MS for the quantification of the LAFIS 10 – an antimalarial candidate – and its pharmacokinetics first evaluationarticle Published on 2015-05-312024-09-01 Journal: Biomedical Chromatography [Category] 말라리아, [키워드] antimalarial Bioanalytical Method Validation LAFIS 10 LC-MS/MS preclinical pharmacokinetics [Article Type] article
New heterocyclic hybrids of pyrazole and its bioisosteres: design, synthesis and biological evaluation as dual acting antimalarial-antileishmanial agentsarticle Published on 2015-04-302024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] 1,3,4-Thiadiazole Antileishmanial antimalarial pyrazole Thiazole Thiazolidinone [Article Type] article