Ultraviolet irradiation doses for coronavirus inactivation – review and analysis of coronavirus photoinactivation studiesArticle Published on 2020-05-142022-11-01 Journal: GMS Hygiene and Infection Control [Category] COVID-19, [키워드] Analysis Antiviral effect appear available data caused condition coronavirus COVID-19 determine Disinfection dose evaluated excluded experiment inactivation irradiation limit median MERS-CoV Modification Mutation new SARS-CoV-2 not differ performed Radiation dose reduction required reveal RNA SARS-CoV SARS-CoV-2 selected Spread the SARS-CoV-2 virus ultraviolet ultraviolet irradiation ultraviolet light Ultraviolet radiation UVC variations virus [DOI] 10.3205/dgkh000343 PMC 바로가기 [Article Type] Article
Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular targetOriginal Article Published on 2020-03-172022-10-31 Journal: EXCLI Journal [Category] COVID-19, [키워드] Analysis Antiviral Antiviral effect Compound contribute coronavirus derivative develop effective epidemiological evaluated feature Features HIV HIV-1 protease inhibitor in silico in silico Approach inhibitor Interaction molecular pharmacology molecular target Novel coronavirus other coronaviruses outbreak protease Protease inhibitor PubChem Ritonavir SARS-CoV SARS-CoV-2 SARS-CoV-2 main protease SARS-CoV-2 treatment sequence Structure three group Treatment viral infections [DOI] 10.17179/excli2020-1189 PMC 바로가기 [Article Type] Original Article
Methionine enkephalin inhibits influenza A virus infection through upregulating antiviral state in RAW264.7 cellsArticle Published on 2020-01-012023-06-24 Journal: International immunopharmacology [Category] 신종인플루엔자, [키워드] Antiviral effect influenza A virus Methionine enkephalin Opioid receptor RAW264.7 cell Toll-like receptors [DOI] 10.1016/j.intimp.2019.106032
Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung CellsArticle Published on 2019-11-042022-10-28 Journal: Biomolecules [Category] Coronavirus, [키워드] activities Anti-inflammatory anticancer antiviral activity Antiviral effect bis-benzylisoquinoline alkaloids Cepharanthine Compound coronavirus early stage expression fangchinoline HCoV-OC43 host response Human human coronavirus human coronavirus strain OC43 human lung cells include Infection inhibited mechanism MRC-5 human lung cell N protein natural natural antiviral OC43 pharmacological Replication significantly Stephania suppressed TET tetrandrine these compound Treatment virus infection virus-induced cell death was reduced [DOI] 10.3390/biom9110696 PMC 바로가기 [Article Type] Article
Investigation of Brassica juncea , Forsythia suspensa, and Inula britannica : phytochemical properties, antiviral effects, and safetyResearch Article Published on 2019-09-112023-05-23 Journal: BMC Complementary and Alternative Medicine [Category] Fulltext, 신종인플루엔자, [키워드] Antiviral effect Human safety Medicinal herbs Phytochemical properties [DOI] 10.1186/s12906-019-2670-x PMC 바로가기 [Article Type] Research Article
Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response미생물총 유래 아세테이트는 GPR43-유형 1 인터페론 반응을 통해 호흡기 세포융합 바이러스 감염으로부터 보호Article Published on 2019-07-222022-09-14 Journal: Nature Communications [Category] 유전자 메커니즘, [키워드] Acetate antiviral activity Antiviral effect Bacteria cytotoxicity dependent on Dietary fiber Effect expression IFN-β IFNAR immunology Infection Innate immunity interferon response interferon-stimulated gene intestinal lung lung epithelial cell Lungs mice microbiota morbidity and mortality oral administration promoted PROTECT protective effect pulmonary epithelial cell pulmonary inflammation receptor reduced reduction respiratory syncytial virus RSV SCFA Type type 1 interferon Viral load Virology [DOI] 10.1038/s41467-019-11152-6 PMC 바로가기 [Article Type] Article
Bafilomycin A1 and U18666A Efficiently Impair ZIKV InfectionArticle Published on 2019-06-062023-08-29 Journal: Viruses [Category] E형 간염, [키워드] Antiviral effect Bafilomycin A1 endosomal–lysosomal compartment U18666A viral life cycle Zika virus [DOI] 10.3390/v11060524 PMC 바로가기 [Article Type] Article
The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expressionResearch Article Published on 2019-05-162022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] abundantly expressed activity addition ADP-ribose ADP-ribosylation Affect antiviral activities Antiviral effect antiviral therapy cellular Coronaviridae coronavirus Coronavirus replication Critical disease enzyme expression facilitate host cell host response human cells identify IFN immune response in vivo independent inhibited inhibitor Innate immunity interferon knockdown less macrodomain Macrophage mice Modification monomer murine mutant mutant virus Mutation PARP PARP12 PARP14 PARPs pathogenic Polymer post-translational modification Prevent Protein Regulation Replication required significantly siRNAs target protein These data Togaviridae virulence virus virus infection virus replication Virus-host interaction viruses while wild-type wild-type virus [DOI] 10.1371/journal.ppat.1007756 PMC 바로가기 [Article Type] Research Article
Synthetic surfactin analogues have improved anti-PEDV propertiesResearch Article Published on 2019-04-112022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] activities analogue antiviral activity antiviral drug Antiviral effect Concentration concentrations Critical cytotoxicity derivative determine develop effective evaluated greater groups inhibiting Like linear PEDV Safe surfactin synthetic utility viral membrane virus [DOI] 10.1371/journal.pone.0215227 PMC 바로가기 [Article Type] Research Article
Antiviral effects against influenza A virus infection by a short hairpin RNA targeting the non-coding terminal region of the viral nucleoprotein geneArticle Published on 2019-03-142023-06-23 Journal: The Journal of veterinary medical science [Category] 신종인플루엔자, [키워드] Antiviral effect influenza A virus RNA interference short hairpin RNA Transgenic mouse [DOI] 10.1292/jvms.18-0436 PMC 바로가기