Reduced antibody activity against SARS-CoV-2 B.1.617.2 delta virus in serum of mRNA-vaccinated individuals receiving tumor necrosis factor-α inhibitors종양 괴사 인자-α 억제제를 투여받는 mRNA 백신 접종 개인의 혈청에서 SARS-CoV-2 B.1.617.2 델타 바이러스에 대한 항체 활성 감소Clinical and Translational Article Published on 2021-11-182022-09-14 Journal: Med (New York, N.Y.) [Category] SARS, 변종, 진단, 치료법, [키워드] Abstract acute respiratory syndrome administration Alpha Analysis antibody Antibody Response B.1.351 B.1.617.2 BNT162b2 BNT162b2 mRNA vaccine center chronic inflammatory disease Cohort Context coronavirus coronavirus disease COVID-19 dose evaluated Fc effector functions finding function capacity funding immunization Immunocompromised immunocompromised individuals immunogenic Immunosuppression immunosuppressive immunosuppressive drug in healthy individuals individual individuals inhibitor inhibitors Innovation less longitudinal lowest monoclonal antibodies monotherapy mRNA vaccine Necrosis neutralization Neutralizing neutralizing antibody Neutralizing antibody titer Neutralizing titer neutralizing titers NIAID Pfizer populations Prevent Prophylaxis protective immunity receiving recipients reduced reductions in required response SARS-CoV-2 SARS-COV-2 infection serum serum antibody serum antibody response Serum neutralizing antibody severe disease strain supported susceptible tested Therapies therapy threshold TNF inhibitors TNF-α treated tumor necrosis factor-α vaccination Vaccine vaccine dose variant variants variants of concern virus [DOI] 10.1016/j.medj.2021.11.004 PMC 바로가기 [Article Type] Clinical and Translational Article
Prevalence of SARS-CoV-2 antibodies in hemodialysis patients in Senegal: a multicenter cross-sectional study세네갈의 혈액 투석 환자에서 SARS-COV-2 항체의 유병률 : 다기관 횡단면 연구Multicenter Study Published on 2021-11-172022-09-01 Journal: BMC Nephrology [Category] MERS, SARS, 진단, [키워드] Abbott African Analysis antibody Architect Asymptomatic disease biological parameter biological parameters blood sample Blood samples clinical clinical symptom Clinical symptoms collected conducted Contact contact with continent COVID-19 cross-sectional cross-sectional survey dialysis eight General population group Hemodialysis Infection information knowledge lethality rate lowest majority medical records multicenter Multivariate analysis nasal swab objective Patient patients patients with SARS-CoV-2 PCR-confirmed performed population density proportion Randomly Region reported Result SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 seroprevalence seeking selected Senegal seroconvert seropositive Seroprevalence Stata Statistical tests Symptom tested the disease Variability [DOI] 10.1186/s12882-021-02582-w PMC 바로가기 [Article Type] Multicenter Study
Machine Learning–Based Predictive Modeling of Anxiety and Depressive Symptoms During 8 Months of the COVID-19 Global Pandemic: Repeated Cross-sectional Survey StudyOriginal Paper Published on 2021-11-172022-10-31 Journal: JMIR Mental Health [Category] COVID-19, [키워드] Additive Adults affected age Algorithm Analysis Anxiety change Combination complex contributing to COVID-19 COVID-19 pandemic cross-sectional data-driven Depression distress Effect elevated emotion emotional emotional distress exacerbate exhibited explained Factor Factors flexible Gender global pandemic Gradient Health highest highlight identify Impact impacted lowest machine machine learning Measures mental health mental illness Model modeling Month objective pandemic Pandemics predicted prediction Principal component principal component analysis proportion question response Result risk sampling strategy second Sociodemographic characteristics Substance use survey Symptom Symptoms variable variables Variation was used were used [DOI] 10.2196/32876 PMC 바로가기 [Article Type] Original Paper
Monoclonal Antibodies against Nucleocapsid Protein of SARS-CoV-2 Variants for Detection of COVID-19COVID-19 검출을 위한 SARS-CoV-2 변이체의 뉴클레오캡시드 단백질에 대한 모노클로날 항체Article Published on 2021-11-172022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법, [키워드] Alpha antibody applied B.1.1.7 B.1.351 B.1.617.2 best Beta binding activity clinical study coronavirus disease Coronavirus disease 2019 coronavirus strain COVID-19 cross-react cycle threshold demonstrated detection diagnostic tests exhibited FIVE HCoV HCoV-19 human coronavirus infected individual infected individuals lateral flow immunoassay Lateral flow immunoassays LFIA LFIAs limit lowest mAb mAbs mice Mitigation monoclonal antibodies monoclonal antibody mutants New nine nucleocapsid protein P.1 pandemic Pathogens purified Rapid diagnostic test Rapid test respiratory Respiratory pathogens SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variants sensitivity specificity TCID the SARS-CoV-2 variant variants Viral viral variant Viral variants virus wild-type [DOI] 10.3390/ijms222212412 PMC 바로가기 [Article Type] Article
Racial differences in institutional trust and COVID-19 vaccine hesitancy and refusalResearch Published on 2021-11-162022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] Affect ALP Asian Asians black collected Community conducted COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine dose Government groups identify indicated Local lowest Native Other Participants race Racial receiving refusal Research response Result Scientific community significant difference significantly higher Strategy The United States the vaccine Trust vaccination Vaccine Vaccine hesitancy vaccine refusal was collected Wave [DOI] 10.1186/s12889-021-12195-5 PMC 바로가기 [Article Type] Research
Emergency Care Gap in Brazil: Geographical Accessibility as a Proxy of Response Capacity to Tackle COVID-19Public Health Published on 2021-11-162022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Accessibility addition administration Analysis Brazil Capacity Care claimed country COVID-19 COVID-19 pandemic Department disease distribution ecological Emergency Epidemiology equipment evaluated Gap HCC Health Health Service Health services accessibility health system highest hospital ICU ICUs identify intensive care lowest measure National New coronavirus Nurses pandemic patients with COVID-19 Physicians physiotherapists professional Public public health Region resource response retrieved retrospective South Spatial analysis System technology ventilator was performed were assessed [DOI] 10.3389/fpubh.2021.740284 PMC 바로가기 [Article Type] Public Health
SARS-CoV-2 Infection Prevalence in the Population of South-Eastern PolandArticle Published on 2021-11-152022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] age Cancer Cancer patients correlation COVID-19 COVID-19 outbreak deaths demographic data detect diagnosed Europe European country Frequency Gender group Healthcare systems highest investigated lowest Poland Population positive RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections Sex significantly significantly lower spread to tested viral infection viral nucleic acid virus detection was used Wuhan, China [DOI] 10.3390/diagnostics11112115 PMC 바로가기 [Article Type] Article
Do racial and ethnic disparities in following stay-at-home orders influence COVID-19 health outcomes? A mediation analysis approachResearch Article Published on 2021-11-112022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] accounted African American Analysis approach Asian association Compliance control variables COVID-19 COVID-19 pandemic demographics determinant Effects examined greater magnitude Health highest infection rate Last lowest median mediation Mediation analysis Mediation effect outcome outcomes Population quantified Racial reducing response Result significantly statistically subject Travel United States white [DOI] 10.1371/journal.pone.0259803 PMC 바로가기 [Article Type] Research Article
Immunosuppressants in Liver Transplant Recipients With Coronavirus Disease 2019: Capability or Catastrophe?—A Systematic Review and Meta-AnalysisMedicine Published on 2021-11-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age Analysis Cardiopulmonary carried Chronic kidney disease CKD Comorbidities Comorbidity Complete coronavirus coronavirus disease COVID-19 database diabetes diagnosis of COVID-19 disease disorders eight heterogeneity hypertension Immunosuppressant Immunosuppression immunosuppressive immunosuppressive therapy inhibitor key consideration less liver liver transplant lowest mammalian Meta-analysis MMF Mortality mortality rate obesity organ pooled rate Prognosis Rapamycin recipient regimen rejection replaced review risk SARS-CoV-2 searched selected severe disease severity significantly Steroids survival the disease the patient therapy Transplant with COVID-19 Withdrawal [DOI] 10.3389/fmed.2021.756922 PMC 바로가기 [Article Type] Medicine
The association between first and second wave COVID-19 mortality in Italy이탈리아의 첫 번째와 두 번째 파도 Covid-19 사망률 사이의 연관성Research Published on 2021-11-112022-09-10 Journal: BMC Public Health [Category] MERS, SARS, 변종, [키워드] Analysis association Community COVID-19 COVID-19 mortality COVID-19 outbreak cubic cubic spline Epidemiology First wave greater implementation initial investigated Italy lowest magnitude measure Mortality mortality data mortality rate outbreak Outbreaks public health Result SARS-CoV-2 second wave Spread study period successive wave successive waves vaccination variant was related Waves [DOI] 10.1186/s12889-021-12126-4 PMC 바로가기 [Article Type] Research