The Role of Nutrients in Prevention, Treatment and Post-Coronavirus Disease-2019 (COVID-19)Review Published on 2022-02-262022-10-31 Journal: Nutrients [Category] COVID-19, [키워드] acute phase approved ARDS cause characterized Coronavirus disease 2019 COVID COVID-19 COVID-19 pandemic disabling symptoms disease Fever human cell immune response immune system infecting Inflammation long-COVID maintain nutrient Nutritional Supplement pandemic Patient Pneumonia preventing infection prevention role Safe SARS-CoV-2 SARS-CoV-2 virus Shortness of breath Spike protein Support supportive care the disease therapy treat weakened WHO World Health Organization [DOI] 10.3390/nu14051000 PMC 바로가기 [Article Type] Review
Monthlong Intubated Patient with Life-Threatening COVID-19 and Cerebral Microbleeds Suffers Only Mild Cognitive Sequelae at 8-Month Follow-up: A Case ReportCase Reports Published on 2022-02-232023-07-06 Journal: Archives of clinical neuropsychology : the official journal of the National [Category] COVID19(2023년), [키워드] ARDS assessment Case report COVID-19 executive functions rehabilitation [DOI] 10.1093/arclin/acab075 PMC 바로가기 [Article Type] Case Reports
Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implicationsSARS-CoV-2 ARDS의 프로테아제-항-프로테아제 구획화: 치료적 의미Articles Published on 2022-02-222022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome airway airways Alpha alpha-1 antitrypsin ARDS ARDS patients balance circulation cleavage cleaved detectable down-regulated Effect elevated evaluated finding IL-6 IL-6 level IL-6 receptor implication induction inhibitor interleukin interleukin-6 investigated involved less Level lung lung parenchyma moderate NET neutrophil Neutrophil elastase Neutrophils occurred patients plasma protease Proteins receptor antagonist regulate respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-CoV-2 ARDS SARS-COV-2 infection secretion Standard of care syndrome target therapy tissue Tocilizumab tracheal were measured [DOI] 10.1016/j.ebiom.2022.103894 PMC 바로가기 [Article Type] Articles
Elevated plasma levels of epithelial and endothelial cell markers in COVID-19 survivors with reduced lung diffusing capacity six months after hospital discharge병원 배출 6 개월 후 폐 확산 능력 감소 된 Covid-19 생존자에서 상피 및 내피 세포 마커의 혈장 수준 증가Observational Study Published on 2022-02-212022-09-01 Journal: Respiratory Research [Category] MERS, 바이오마커, 임상, 진단, [키워드] abnormality acute disease acute respiratory distress acute respiratory distress syndrome Adhesion Molecule angiopoietin ARDS carbon monoxide Cell Characteristics circulating clinical Clinical characteristics COVID-19 diffusing diffusing capacity discharge disease DLCO Dyspnoea E-selectin elevated endothelial Endothelial cell endothelial marker Endothelial markers epithelial Epithelial markers Follow-up hospital discharge Hospitalization hypertension independent risk factor independent risk factors individuals intercellular intercellular adhesion molecule leukocyte Level lung lung damage Lung function marker multivariate regression analysis observational study Occurrence Older Organizing pneumonia pathophysiology Patient patients plasma Plasma levels Pneumonia Post-COVID Prospective Protease inhibitor Protein Pulmonary embolism pulmonary embolisms reduced respiratory distress Result risk factor Risk factors selectin Sequelae severe COVID-19 severity Severity Score SLPI Smokers spirometry suffered supplementary material survivor Survivors syndrome [DOI] 10.1186/s12931-022-01955-5 PMC 바로가기 [Article Type] Observational Study
Treatment of COVID-19-associated ARDS with mesenchymal stromal cells: a multicenter randomized double-blind trialRandomized Controlled Trial Published on 2022-02-212022-10-04 Journal: Critical Care [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] 95% CI acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome analyzed ANCOVA ARDS assigned baseline cause change Coronavirus-2 Course COVID-19-associated ARDS double-blind double-blind trial Efficacy eligibility enrolled fractional inspired oxygen French Good-manufacturing practice high mortality intravenous intravenous infusion modified intention-to-treat multicenter multicentre NaCl not differ oxygen PaO Patient Placebo placebo group placebo-controlled trial Randomized Randomly receive recipient recruited recruitment Result screened Serious Adverse Event Serious Adverse Events severe acute respiratory syndrome coronavirus-2 significantly stromal cell supplementary material syndrome the primary endpoint Treatment Trial UC-MSC UC-MSCs Umbilical cord-derived mesenchymal stromal cells [DOI] 10.1186/s13054-022-03930-4 PMC 바로가기 [Article Type] Randomized Controlled Trial
Efficacy of diammonium glycyrrhizinate combined with vitamin C for treating hospitalized COVID-19 patients: a retrospective, observational studyObservational Study Published on 2022-02-212022-10-05 Journal: QJM: An International Journal of Medicine [Category] COVID19(2023년), SARS, 임상, [키워드] Acute liver injury acute respiratory distress acute respiratory syndrome Admission adopted Analysis approach ARDS assigned caused Cohort combination treatment Complication coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients decrease Deterioration determine group groups help hospitalized COVID-19 incidence rate medical treatments myocardial injury NK cell observé pandemic Participants Patient patients with COVID-19 Perspective propensity score matching PSM recruited response retrospective SARS-CoV-2 shown syndrome therapy Tongji Hospital Treatment Vitamin C was used [DOI] 10.1093/qjmed/hcab184 PMC 바로가기 [Article Type] Observational Study
Naïve Human Macrophages Are Refractory to SARS-CoV-2 Infection and Exhibit a Modest Inflammatory Response Early in InfectionArticle Published on 2022-02-212022-10-28 Journal: Viruses [Category] COVID-19, COVID19(2023년), Fulltext, SARS, 신종인플루엔자, [키워드] absence acute respiratory distress ARDS COVID-19 patients cytokine cytokine level cytokine response Cytokine storm Cytokines driven by excessive secretion expression external gene Factor H1N1 H5N1 Heterologous highly pathogenic Human human monocyte-derived macrophage hyperinflammation IFN-α IFN-β Infectivity Influenza Influenza virus influenza viruses Involvement M gene Macrophage macrophages MDM notable pathogenic Plaque assay Proinflammatory cytokine proteome qRT-PCR refractory replicated Replication response SARS-CoV-2 SARS-COV-2 infection semiquantitatively stimulated susceptible syndrome TCID virus were assessed [DOI] 10.3390/v14020441 PMC 바로가기 [Article Type] Article
High procalcitonin levels associated with increased intensive care unit admission and mortality in patients with a COVID-19 infection in the emergency department응급실에서 COVID-19 감염 환자의 집중 치료실 입원 및 사망률 증가와 관련된 높은 Procalcitonin 수준Research Article Published on 2022-02-212022-09-10 Journal: BMC Infectious Diseases [Category] COVID19(2023년), Fulltext, MERS, SARS, 바이오마커, [키워드] 105 patient 105 patients 95% CI 95% confidence interval acute respiratory distress acute respiratory distress syndrome adjusted Admission age Analysis ARDS assist association AUC Bacterial bacterial coinfections Biomarker Biomarkers C-reactive protein C-reactive protein (CRP calculate center clinical decision Comorbidities Comorbidity Confirmed COVID-19 infection COVID-19 COVID-19 infection COVID-19 infections CRP D-dimer Decision making decision making process defined develop elevated emergency department Erasmus Final final analysis hospital discharge Hospital mortality hyperinflammation ICU ICU admission in-hospital mortality intensive care intensive care unit Logistic regression Mortality multivariable model Netherlands Odds ratio outcome Patient patients with COVID-19 PCT physician Primary outcome procalcitonin procalcitonin level reached required respiratory distress Respiratory distress syndrome Result retrospective cohort study Severe COVID-19 Infection severe COVID-19 infections Sex significantly supplementary material syndrome were measured [DOI] 10.1186/s12879-022-07144-5 PMC 바로가기 [Article Type] Research Article
The Use of a Video-Assisted Intubating Stylet Technique in a Critically Ill and Contagious COVID-19 PatientCase Report Published on 2022-02-182022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] acute respiratory distress addition airway airway management ARDS Case report Consensus contagious COVID-19 COVID-19 patient Critically ill demonstrated effective equipment Ill infected with COVID-19 intubate intubating intubating stylet intubation Laryngoscopy Patient risk of COVID-19 Safe severe hypoxia Stylet syndrome technique tracheal tracheal intubation Treatment ventilatory support [DOI] 10.3390/healthcare10020388 PMC 바로가기 [Article Type] Case Report
Pitfalls of Early Systemic Corticosteroids Home Therapy in Older Patients with COVID-19 PneumoniaBrief Report Published on 2022-02-172022-10-31 Journal: Geriatrics [Category] COVID-19, [키워드] acute respiratory distress Administered Admission age ARDS benefit Care Clinical outcome clinical outcomes Control corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 determine early phase ECT Effectiveness enrolled Escalation home home therapy Hospitalization Hospitalized ICU in-hospital mortality median no difference older patient older people pandemic PaO Patient Pneumonia progression progression of disease reducing SARS-COV-2 infection significant difference SOFA score subject syndrome systemic the disease transfer with COVID-19 [DOI] 10.3390/geriatrics7010021 PMC 바로가기 [Article Type] Brief Report