Discrimination of SARS-CoV-2 Omicron Sublineages BA.1 and BA.2 Using a High-Resolution Melting-Based Assay: a Pilot StudyArticle Published on 2022-08-312022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome Analysis BA.1 BA.2 Care clinical sample clinical samples continuous monitoring coronavirus COVID-19 Delta determine develop discrimination domain High-resolution high-resolution melting identify L452R mutant Mutation Next-generation sequencing omicron Omicron variant Patient R408 Receptor-binding domain Region replacing RNA SARS-CoV-2 screening method Sensitivity and specificity severe disease significantly spike receptor-binding domain Spread T478K the SARS-CoV-2 time-consuming Transmission variant wild-type [DOI] 10.1128/spectrum.01367-22 PMC 바로가기
Performance of 22 Rapid Lateral Flow Tests for SARS-CoV-2 Antigen Detection and Influence of “Variants of Concern”: Implications for Clinical UseArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome Alpha Antigen clinical collected coronavirus Cutoff cycle threshold detect detection evaluate evaluated exhibited false-positive result False-positive results Flow head-to-head assessment influence Lateral lateral-flow tests less majority NAAT nucleic acid amplification Occurrence Omicron variant Omicron variants other variants Paris performance proportion ranged Rapid reduced required SARS CoV-2 SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 viral sensitivity Sensitivity and specificity specificity symptom onset Test tested variants variants of concern Viral load Viral variants virus VoC [DOI] 10.1128/spectrum.01157-22 PMC 바로가기
Analytical Sensitivity of Eight Different SARS-CoV-2 Antigen-Detecting Rapid Tests for Omicron-BA.1 VariantArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] SARS, 변종, 치료기술, [키워드] Ag-RDT Ag-RDTs analytical sensitivity Antigen-detecting rapid diagnostic tests Biological Breakthrough infection circulating clinical sample comparable COVID-19 cultured virus Delta detect detectable diagnostic diagnostic test duplicate eight Endpoint generate Infection prevention investigated Measures omicron Omicron variant Omicron-BA.1 variant performed positive Rapid Rapid diagnostic test retrospective Retrospective study SARS-CoV-2 SARS-CoV-2 variant sensitivity Seven Test vaccinated individual variant variants of concern VoC VOCs [DOI] 10.1128/spectrum.00853-22 PMC 바로가기
Susceptibility of SARS-CoV-2 Omicron Variants to Therapeutic Monoclonal Antibodies: Systematic Review and Meta-analysisArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibody Antiviral antiviral therapy clinical development Combination combinations conserved COVID-19 Critical Determining disparate effective eight eligible in vitro in vitro activity inactive interquartile range loss of activity measure median monoclonal monoclonal antibody Multidrug resistance Mutation neutralization omicron Omicron variant receptor-binding domains reduced reduction in Region reported review SARS-CoV-2 Spike protein spike receptor-binding domain Standardization susceptibility the median the SARS-CoV-2 therapeutic treating COVID-19 variant variants wild-type [DOI] 10.1128/spectrum.00926-22 PMC 바로가기
Antibody and Memory B-Cell Immunity in a Heterogeneously SARS-CoV-2-Infected and -Vaccinated PopulationArticle Published on 2022-08-302022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] accumulating acute respiratory syndrome Adenovirus antibody B-cell B.1.1.529 Combination coronavirus correlated country determine distribution elicited FIVE help heterogeneous immune immune evasion immune response Immunity individuals Infection less Level majority memory B memory B cells memory B-cell mRNA Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody titers Omicron variant platform Population population immunity prefusion recipient SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant single vaccine spike trimer the vaccine undetectable vaccination Vaccine [DOI] 10.1128/mbio.00840-22 PMC 바로가기
Trends in Confirmed COVID-19 Cases in the Korean Military Before and After the Emergence of the Omicron VariantArticle Published on 2022-08-292022-11-16 Journal: Journal of Korean medical science [Category] SARS, 변종, [키워드] 95% confidence interval acute respiratory syndrome adjusted Analysis analyzed Confirmed confirmed COVID-19 case coronavirus coronavirus disease Coverage COVID-19 COVID-19 incidence emergence Immune escape incidence rate Intensive Interrupted Interrupted time-series analysis Korean Military personnel occurred Occurrence omicron Omicron variant outbreak Patient SARS-CoV-2 SARS-CoV-2 Omicron variant significantly increased Transmissibility trend vaccination was performed [DOI] 10.3346/jkms.2022.37.e260 PMC 바로가기
A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variantsArticle Published on 2022-08-252022-11-15 Journal: eLife [Category] SARS, 변종, 진단, [키워드] antibody BBIBP-CorV booster Breakthrough infection broad-spectrum circulating variants combating COVID-19 COVID-19 vaccine cross-neutralizing antibody develop effective elicited homologous immunogenic immunology inactivated indicate induce Infectious disease Inflammation Microbiology Mutation neutralization omicron Omicron variant pandemic Population RBD SARS-CoV-2 SARS-CoV-2 variant spike receptor-binding domain Test trimeric Vaccine vaccine candidate Vaccines variants viruses with COVID-19 [DOI] 10.7554/eLife.78633 PMC 바로가기
Managing an evolving pandemic: Cryptic circulation of the Delta variant during the Omicron rise진화하는 전염병 관리: 오미크론 상승 중 Delta 변종의 비밀 순환Article Published on 2022-08-252022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Chain Reaction Characteristics circulation decrease Delta delta variant diminishe dominant eliminated Epidemiology expected Increases indicated initial maintain managing morbidity Mutation omicron Omicron variant pandemic polymerase chain polymerase chain reaction Quantitative real time reverse transcriptase Reverse transcriptase quantitative polymerase chain reaction RT-qPCR SARS-CoV-2 side Spread Susceptible-infected-recovered model variant variants variants of concern Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2022.155599 PMC 바로가기 [Article Type] Article
Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Subvariant BA.2 in a Single-Source Community Outbreak단일 출처 커뮤니티에서 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 오미크론 하위 변종 BA.2의 급속한 확산Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed Asia BA.2 sublineage calculated Cluster Community community outbreak coronavirus coronavirus 2 COVID-19 doubling epidemiological epidemiologically Europe genomic Genomic analysis highlight Hong Kong housing estate. individual information involved lockdown measure Mutation omicron Omicron variant outbreak Oxford Nanopore MinION Patient performed Phylogenetic analysis Rapid respiratory SARS-CoV-2 SARS-CoV-2 Omicron variant sequence Sequencing severe acute respiratory syndrome Coronavirus Surveillance Transmissibility unique variant Viral genome sequencing was performed whole-genome sequencing [DOI] 10.1093/cid/ciac203 PMC 바로가기 [Article Type] Article
Rapid Control of Hospital-Based Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Clusters Through Daily Testing and Universal Use of N95 RespiratorsN95 호흡기의 일상적인 테스트와 보편적인 사용을 통한 병원 기반 중증 급성 호흡기 증후군 코로나바이러스 2오미크론 클러스터의 신속한 제어Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Admission Cluster Clusters contagious Control coronavirus coronavirus 2 Daily increase increases in Infection N95 respirator nosocomial Nosocomial infection Nosocomial transmission omicron Omicron variant Prevent Rapid Respirator respiratory risk SARS-CoV-2 Symptom Testing Transmission transmissions Universal variant [DOI] 10.1093/cid/ciac113 PMC 바로가기 [Article Type] Article