COVID-19 uncertainty and sleep: the roles of perceived stress and intolerance of uncertainty during the early stage of the COVID-19 outbreakResearch Published on 2021-06-142022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] Analysis analyzed applied asleep autonomous China Chinese conducted COVID-19 COVID-19 outbreak COVID-19 pandemic Critical cross-sectional early stage Factor implication Infection intolerance of uncertainty less lockdown measure Mediation analysis outbreak outcomes participant Perceived stress Poor sleep positively correlated provided quarantine Region reported Result robust significantly Stress supplementary material total score Uncertainty about COVID-19 [DOI] 10.1186/s12888-021-03310-2 PMC 바로가기 [Article Type] Research
Viral loads, lymphocyte subsets and cytokines in asymptomatic, mildly and critical symptomatic patients with SARS-CoV-2 infection: a retrospective studySARS-COV-2 감염을 앓고있는 무증상, 경미하고 중요한 증상 환자의 바이러스 부하, 림프구 서브 세트 및 사이토 카인 : 후 향적 연구Comparative Study Published on 2021-06-122022-09-01 Journal: Virology Journal [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission age ANOVA Asymptomatic asymptomatic individual Asymptomatic individuals asymptomatic patient asymptomatic patients attack B cell B cells biological microscope Cell Chi-square Concentration coronavirus coronavirus disease coronavirus disease-2019 correlated COVID-19 Critical Critical case cytokine Cytokines diabetes Diabetes Mellitus disease enrolled Fisher Fisher's exact test flow cytometer Flow cytometric analysis group hospital Hospitalization IFN-α IFN-γ IL-10 IL-2 IL-5 IL-6 IL-8 IL10 IL2 IL4 IL5 IL6 IL8 infected individuals interleukin laboratory characteristics lymphocyte Lymphocyte subset Lymphocytes lymphopenia marker Microscope Mild Mild symptom mild symptoms NK cell NK cells No statistical differences occurred Patient patients patients with COVID-19 Plasma cytokine Pneumonia positively correlated respiratory Respiratory system Result Retrospective study RT-PCR SARS-CoV-2 SARS-COV-2 infection SCS severe acute respiratory syndrome Coronavirus severity of COVID-19 significant difference source of infection sputum statistical difference statistical differences subject subset symptomatic patient Symptomatic patients T cells T lymphocytes throat-swab TNF-α underlying disease underlying diseases variance Viral Viral load viral loads was used with COVID-19 [DOI] 10.1186/s12985-021-01597-x PMC 바로가기 [Article Type] Comparative Study
Unbiased Analysis of Temporal Changes in Immune Serum Markers in Acute COVID-19 Infection With Emphasis on Organ Failure, Anti-Viral Treatment, and Demographic Characteristics장기 실패, 항 바이러스 치료 및 인구 통계 학적 특성에 중점을 둔 급성 코비드 -19 감염에서 면역 혈청 마커의 시간적 변화에 대한 편견없는 분석Immunology Published on 2021-06-112022-08-31 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 진단, [키워드] 48 hour 48 hours Admission age analyzed Biomarker Biomarkers CCL23 CD28 change chemokine chemokines collected condition convalescent plasma correlated Course COVID-19 COVID-19 admission Deceased decorin demographic demographics demonstrated elevated failure GzmB heterogeneity Hydroxychloroquine ICU identification IL-15 IL-18 immune immunological increased expression individual kidney Kidney failure lack LAG3 LAMP3 ligands Longitudinal studies MCP MCP-1 MCP-3 monocyte Mortality Older age pathology pleiotrophin positively correlated programmed death Protein proteomics remdesavir Remdesivir respiratory serum serum levels Serum Marker Seven severity of COVID-19 steroid Steroids target Temporal the disease therapeutic TNFRSF21 Variation VEGF with COVID-19 [DOI] 10.3389/fimmu.2021.650465 PMC 바로가기 [Article Type] Immunology
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral targetSARS-CoV-2 외피 단백질은 급성 호흡곤란 증후군(ARDS)과 유사한 병리학적 손상을 유발하고 항바이러스 표적을 구성합니다.Article Published on 2021-06-102022-09-11 Journal: Cell Research [Category] MERS, SARS, 바이오마커, 변종, 유전자 메커니즘, 진단, 치료제, [키워드] activity acute respiratory distress acute respiratory distress syndrome administration angiotensin Anti-SARS-CoV-2 Activity antiviral target ARDS cation channels cause caused Cell cell death cell types channel inhibitor chemokine chemokines cytokine Cytokine storm Cytokines damages death dominant negative drug target exhibited expressing heterologous expression human Angiotensin-converting enzyme Human angiotensin-converting enzyme 2 in vitro in vivo infected cells Inflammation inhibitor Intravenous administration lung Lungs macrophages membranes mice Molecular biology multi-organ failure Mutation positively correlated Prophylactic Protective Protein purified reduced respiratory distress robust SARS-CoV-2 SARS-CoV-2 envelope SARS-CoV-2-infected cells secretion spleen Support susceptible cell syndrome the SARS-CoV-2 therapeutic transgenic mice Viral Viral load [DOI] 10.1038/s41422-021-00519-4 PMC 바로가기 [Article Type] Article
T2-mapping increase is the prevalent imaging biomarker of myocardial involvement in active COVID-19: a Cardiovascular Magnetic Resonance studyT2 매핑 증가는 활성 COVID-19에서 심근 관련의 일반적인 이미징 바이오마커입니다: 심혈관 자기 공명 연구Observational Study Published on 2021-06-102022-09-10 Journal: Journal of Cardiovascular Magnetic Resonance [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] Abnormalities abnormality active phase Artery Biomarker cardiovascular Cardiovascular Magnetic Resonance change characterization clinical Cohort collected Comparisons control group Coronary arteries coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 diagnosis COVID-19 patients cTnT decrease Diagnosis disease Early detection edematous enrolled Evidence evidence of Extracellular fraction gadolinium healthy control healthy controls in vivo individual individuals Infection Inflammation IQR Laboratory laboratory characteristics laboratory findings linear correlation median moderate Myocardial myocardial damage Myocardial infarction myocardial injury myocardial involvement myocarditis Observational cohort study Occurrence parameters Patient patients Pericarditis positive linear correlation positively correlated predominant prevalent protocol Quantitative imaging referred to relationship resonance Result retrospective risk risk factor SARS-CoV-2 selected sensitivity Sex supplementary material Symptomatic treatment time interval tissue troponin troponin T Volume volume fraction [DOI] 10.1186/s12968-021-00764-x PMC 바로가기 [Article Type] Observational Study
CT appearances, patterns of progression, and follow-up of COVID-19: evaluation on thin-section CTOriginal Article Published on 2021-06-102022-10-29 Journal: Insights into Imaging [Category] COVID-19, [키워드] absorbed Analysis Chest CT consolidation COVID-19 CT finding Deterioration evaluated exhibited fluctuation Follow-up GGO Hospitalization infectious disease medicine initial interval intervals lesion Multidetector computed tomography observé Patient patients patients with COVID-19 Pneumonia positively correlated progression pulmonary lobe remained Result Viral pneumonia [DOI] 10.1186/s13244-021-01019-0 PMC 바로가기 [Article Type] Original Article
Correlation between interleukin gene polymorphisms and current prevalence and mortality rates due to novel coronavirus disease 2019 (COVID‐2019) in 23 countriesResearch Article Published on 2021-06-102022-11-01 Journal: Journal of medical virology [Category] COVID-19, MERS, SARS, [키워드] Brazil caused China Coronavirus disease 2019 correlated correlation country COVID‐19 Croatia explained Frequency genetic background Genotype Germany Greece IL‐17A IL‐6 India Infection Inflammatory response interleukin Iran Italy Japan loci mortality rate negative correlation Netherlands Norway novel coronavirus disease Poland polymorphism Population positive correlation positively correlated Prevalence recorded Result rs2228145 rs2275913 Russia searched significant negative correlation South Africa Spain Turkey Variation [DOI] 10.1002/jmv.27127 PMC 바로가기 [Article Type] Research Article
Correlation Analysis between the Viral Load and the Progression of COVID-19바이러스 부하와 COVID-19의 진행 사이의 상관관계 분석Research Article Published on 2021-06-082022-09-11 Journal: Computational and Mathematical Methods in Medicine [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] 2019 novel coronavirus acid biochemical blood routine examination C-reactive protein C-reactive protein (CRP clinically collected conversion coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 patient CRP Ct value cycle threshold demonstrated detection determined by Disease progression examined guideline immune response indicated key factor load lymphocyte Lymphocyte count Mild neutrophil neutrophil count novel Novel coronavirus nucleic acid nucleic acid test nucleic acid testing nucleocapsid protein objective Patient Pneumonia positively correlated progression Protein R 2 respiratory respiratory tract specimen respiratory tract specimens Result resulting SARS-CoV-2 Severe case severe COVID-19 severe disease significantly suggested the disease throat swabs underlying diseases Viral Viral load was measured [DOI] 10.1155/2021/9926249 PMC 바로가기 [Article Type] Research Article
Influencing Factors of Psychosocial Stress among Korean Adults during the COVID-19 OutbreakArticle Published on 2021-06-072022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] affected conducted correlated COVID-19 COVID-19 cases COVID-19 pandemic cross-sectional determine Factor Health health belief Health status increase indicated individual knowledge Korean lockdown no difference participant participated positively correlated Psychosocial Psychosocial stress quarantine Resilience [DOI] 10.3390/ijerph18116153 PMC 바로가기 [Article Type] Article
Meteorological factors against COVID-19 and the role of human mobilityResearch Article Published on 2021-06-042022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] compensated correlation country COVID-19 driving Effect effect of temperature Factor Factors fatality FIVE Increasing indirect effect Interaction outbreak positive positively correlated Previous studies Radiation reduce significantly social distancing Spread survival temperature variables virus [DOI] 10.1371/journal.pone.0252405 PMC 바로가기 [Article Type] Research Article