Evolution of SARS-CoV-2-Neutralizing Antibodies after Two Standard Dose Vaccinations, Risk Factors for Non-Response and Effect of a Third Dose Booster Vaccination in Non-Responders on Hemodialysis: A Prospective Multi-Centre Cohort StudyArticle Published on 2021-10-302022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI age Antibody titer booster booster vaccination chronic hemodialysis patient chronic hemodialysis patients Cohort Control control group controls COVID-19 determine dosage dose Effect effective Factor healthy control Hemodialysis IgG antibody IgG antibody titer IgG titer immunosuppressive Immunosuppressive medication increase in induce Logistic regression analysis Major Neutralizing Neutralizing antibodies Odds ratio offered Older age participant Patient patients Probability Prospective Protective reduced responders response to vaccination Result risk factor risk factors for non-response SARS-CoV-2 SARS-CoV-2 IgG antibody SARS-CoV-2 vaccination second dose Seven Standard the healthy the patient therapy vaccination vaccine doses virus-neutralizing was used were measured [DOI] 10.3390/jcm10215113 PMC 바로가기 [Article Type] Article
Acute Kidney Injury and Renal Replacement Therapy in COVID-19 Versus Other Respiratory Viruses: A Systematic Review and Meta-AnalysisCOVID-19 Collection Published on 2021-10-302022-10-31 Journal: Canadian Journal of Kidney Health and Disease [Category] COVID-19, [키워드] 95% confidence interval ACE2 Acute kidney injury Admission age AKI Alter angiotensin converting enzyme 2 article articles association calculate Chronic kidney disease conducted coronavirus 2 coronavirus disease-2019 COVID-19 COVID-19 patient COVID-19 patients Critical illness Critically ill Critically ill patient defined Diabetes Mellitus downregulate enzyme estimate exclusion criteria fatal complication Frequency groups heterogeneity Hospitalized hospitalized patient hypertension ICU ICU admission Impact in viral include Influenza inhibitor intensive care Kidney injury Last limitation logistic regression model MERS Meta-analysis Middle East modulation Mortality MOST not significantly different observational study Other Patient patients patients with COVID-19 performed Prospective random effect random intercept receptor renal replacement therapy replacement respiratory respiratory viral infection respiratory virus responsible retrospective review RRT SARS-CoV-2 searched Severity of infection Sex Shock significantly System systematic review Vasopressor virus viruses were infected were used with COVID-19 [DOI] 10.1177/20543581211052185 PMC 바로가기 [Article Type] COVID-19 Collection
Functional Activity of the Complement System in Hospitalized COVID-19 Patients: A Prospective Cohort StudyObservational Study Published on 2021-10-282022-10-04 Journal: Frontiers in Immunology [Category] MERS, SARS, 임상, [키워드] 95% CI Activation activity acute lung injury acute phase Admission Alternative pathway Analysis autopsy studies C1 esterase inhibitor collected complement complement system Concentration confounding factors correlated COVID-19 COVID-19 patient Critically ill death Disease progression disease severities disease severity Factor ficolin-3 Follow-up hospitalized COVID-19 patient hospitalized patient ICU admission implicated in vitro in vivo In-hospital death Inflammation Inflammatory marker IQR lectin pathway male mannose-binding lectin mechanical ventilation median multiple comorbidities no significant difference occurred Pathogenesis pathway Patient PCR-confirmed Primary outcome progression Prospective prospective observational study Protein reduced required Result resulting ROC Curve SARS-CoV-2 SARS-COV-2 infection serum sample severe COVID-19 severe disease significantly significantly lower single-center System the patient threshold Ventilation [DOI] 10.3389/fimmu.2021.765330 PMC 바로가기 [Article Type] Observational Study
Clinical management and outcome differences between first and second waves among COVID-19 hospitalized patients: A regional prospective observational cohortObservational Study Published on 2021-10-282022-10-04 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] adjusted clinical Clinical characteristics Cohort cohort study consecutive patient COVID-19 creatinine D-dimer level discharge Epidemic epidemiological hospital Hospital admission Hospital stay Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient ICU admission IMPROVE management mechanical ventilation Mortality New no significant difference observé Older outbreak outcome PaO2/FiO2 ratio Patient prognostic Prospective reduced required second wave therapeutic Treatment [DOI] 10.1371/journal.pone.0258918 PMC 바로가기 [Article Type] Observational Study
Determinants and Dynamics of SARS-CoV-2 Infection in a Diverse Population: 6-Month Evaluation of a Prospective Cohort Study다양한 인구에서 SARS-CoV-2 감염의 결정 요인 및 역학: 예비 코호트 연구의 6개월 평가Observational Study Published on 2021-10-282022-09-11 Journal: The Journal of Infectious Diseases [Category] MERS, SARS, 임상, 진단, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted odds ratio affected antibodies antibody Asymptomatic asymptomatic infection asymptomatic infections Chain Reaction change Cohort Comorbidities coronavirus correlated COVID-19 determinant Dynamics Dyspnea healthcare worker Healthcare workers hospital humoral Humoral immunity IgG IgG antibodies IgG antibody IgG response IgG responses IgG titer IgG titers Immunoglobulin Immunoglobulin G Increases Infection Longitudinal data longitudinal data analysis magnitude median MOST Multivariable models neurologic Odds ratio participant Participants polymerase chain polymerase chain reaction postacute sequelae of COVID-19 Prolonged Prospective prospective cohort Registration respiratory risk Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 polymerase chain reaction severe acute respiratory syndrome Coronavirus severe symptoms Symptom symptom severity symptomatic symptomatic infection symptomatic infections Symptoms tested trajectory [DOI] 10.1093/infdis/jiab411 PMC 바로가기 [Article Type] Observational Study
It Is Not Just the FEV1 That Matters, but the Personal Goals We Reach Along the Way: Qualitative, Multicenter, Prospective, Observational StudyObservational Study Published on 2021-10-202022-10-04 Journal: Journal of Medical Internet Research [Category] MERS, SARS, 임상, [키워드] app application Asthma asthma control Care Child Consensus COVID-19 pandemic disease effective eHealth expiratory FEV FEV1 Frequency Goal hcp Health home monitoring implementation individuals Intervention IQR Lung function lung function tests median mHealth multicenter objective outcome outpatients participant Patient patient care management pediatric asthma pediatrics perceived benefit Perspective professional Prospective pulmonary care Qualitative Quality improvement receiving reliability remained remote consultations Result secondary Self-management Smartphone spirometry study period survey telemetry Telemonitoring Validity Volume were used [DOI] 10.2196/29218 PMC 바로가기 [Article Type] Observational Study
COVID-19 among Healthcare Workers: A Prospective Serological-Epidemiological Cohort Study in a Standard Care Hospital in Rural Germany의료 종사자 사이의 COVID-19: 독일 시골의 표준 치료 병원에서 전향적 혈청학적-역학적 코호트 연구Communication Published on 2021-10-192022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 진단, 치료기술, [키워드] administration antibody Cohort Contact contribute COVID-19 COVID-19 infections epidemiological Germany group HCW healthcare healthcare worker Healthcare workers hospital Immunity increased risk Infection intensive care intensive care unit management measure outcome pandemic Prevalence prevalence rate prevalence rates primary care Prospective risk risk of COVID-19 risk of infection SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 pandemic Seroprevalence significantly higher staff Standard the SARS-CoV-2 virus spread was determined [DOI] 10.3390/ijerph182010999 PMC 바로가기 [Article Type] Communication
Coronavirus Disease 2019 Vaccine Impact on Rates of Severe Acute Respiratory Syndrome Coronavirus 2 Cases and Postvaccination Strain Sequences Among Health Care Workers at an Urban Academic Medical Center: A Prospective Cohort StudyMajor Articles Published on 2021-10-172022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] acute respiratory syndrome antibody escape mutations Asymptomatic Breakthrough infection Community Confidence intervals confirmed case coronavirus coronavirus 2 Coronavirus disease 2019 COVID-19 COVID-19 vaccine decrease dose dropped first dose genetic diversity Genome HCW HCWs Health care worker Impact infection control infections initial injection isolate Latinx mRNA-1273 Mutation occurred of BNT162b2 Older positive Prevalence Prospective prospective cohort study Rate rate ratio respiratory Result SARS-CoV-2 SARS-CoV-2 infections selection pressure sequence sequenced Spike protein strain urban vaccination Vaccine vaccine doses vaccine trial viral evolution Weekly Whole genome sequencing with COVID-19 worker [DOI] 10.1093/ofid/ofab465 PMC 바로가기 [Article Type] Major Articles
Dynamic metabolic changes measured by indirect calorimetry during the early phase of septic shock: a prospective observational pilot study Research Published on 2021-10-152022-10-05 Journal: European journal of clinical nutrition [Category] 바이오마커, [키워드] Analysis change changed collected criterion dynamic early phase eligible energy Evolution favor Final ICU intensive care lipids metabolic metabolism oxygen Patient Physiology pilot study Prospective Protein Proteins Quotient remained Result score Septic shock significant decrease significantly study period substrate substrates Support surgical time Variation Ventilated [DOI] 10.1038/s41430-021-01012-2 [Article Type] Research
Telehealth-Based Family Conferences with Implementation of Shared Decision Making Concepts and Humanistic Communication Approach: A Mixed-Methods Prospective Cohort StudyArticle Published on 2021-10-142022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] approach clinical encounter communication concept conducted Conference Contact COVID-19 COVID-19 pandemic Decision making distress emotional expression family family conference filtered healthcare help IMPROVE Intention lack Likert scale National pandemic Patient physician Prospective respond Safe Satisfaction satisfaction score shared-decision making Taiwan telehealth the patient therapeutic relationship value verbal [DOI] 10.3390/ijerph182010801 PMC 바로가기 [Article Type] Article