Methodological Analysis: Randomized Controlled Trials for Pfizer and Moderna COVID-19 Vaccines방법론적 분석: Pfizer 및 Moderna COVID-19 백신에 대한 무작위 대조 시험Article Published on 2021-07-012022-09-11 Journal: Journal of pediatric health care : official public [Category] SARS, 임상, [키워드] Analysis appraisal Cambridge Care Casp CASP critical appraisals checklist checklist Community conducted Controlled coronavirus COVID-19 COVID-19 disease critical appraisal determine develop distribution Efficacy Health Health care item methodology Moderna morbidity and mortality MOST New York outcome Pfizer Population populations positive question Randomized randomized control trial Randomized controlled trial Randomized controlled trials RCT RCTs reduce Reporting reporting guidelines. rigor rigorous analysis scored skill Standard the vaccine Vaccinations Vaccine Vaccine hesitancy [DOI] 10.1016/j.pedhc.2021.04.001 PMC 바로가기 [Article Type] Article
The Reward Re-Training protocol: A novel intervention approach designed to alter the reward imbalance contributing to binge eating during COVID-19Randomized Controlled Trial Published on 2021-07-012022-10-05 Journal: The International journal of eating disorders [Category] 임상, [키워드] activities activity Alter approach assessment baseline binge eating characterized conditions conducted contributing to COVID-19 COVID-19 pandemic Critical disorder eating disorders Efficacy elevated engage estimate evaluate feasibility Follow-up group therapy include individual Intervention loneliness palatable participant protocol Randomized Randomized controlled trial RCT reduced reducing Registered response reward. RRT social isolation Symptom Symptoms target targets therapy Treatment [DOI] 10.1002/eat.23528 PMC 바로가기 [Article Type] Randomized Controlled Trial
CariesCare International adapted for the pandemic in children: Caries OUT multicentre single-group interventional study protocolStudy Protocol Published on 2021-07-012022-10-28 Journal: BMC Oral Health [Category] COVID-19, Fulltext, SARS, [키워드] activities Aerosols baseline calculated Care Cary CCI children Clinical data Comprehensive Conservative care country COVID-19 COVID-19 pandemic Dental care Dental caries dental practitioner diagnose Effectiveness Health help Intervention lesion management multicenter study multicentre outcome outcome assessment outcomes pandemic Patient Patient satisfaction personalised progression Questionnaires RCT reduced reducing Remote Consultation risk Sample size severity shifting shown Study protocol supplementary material Support Symptoms the patient tooth Trial [DOI] 10.1186/s12903-021-01674-1 PMC 바로가기 [Article Type] Study Protocol
A literature review of consent declines and consent withdrawals in randomized controlled trials conducted during the COVID-19 pandemicCOVID-19 전염병 동안 수행된 무작위 대조 시험에서 동의 거부 및 동의 철회에 대한 문헌 검토Review Published on 2021-07-012022-09-11 Journal: Journal of postgraduate medicine [Category] SARS, 임상, [키워드] analysed conducted Consent Consent declines consent withdrawal Control Controlled trial controls COVID-19 COVID-19 pandemic COVID-19 RCT COVID-19 RCTs Decline evaluated filtered interim analysis literature review Missing data Non-COVID-19 observational studies pandemic participant primary outcome measure Primary outcome measures proportion protocols Randomized Randomized controlled trial RCT RCTs screened searched significant difference significantly lower Topic Vaccine Withdrawal [DOI] 10.4103/jpgm.JPGM_77_21 PMC 바로가기 [Article Type] Review
The effect of tocilizumab on COVID-19 patient mortality: A systematic review and meta-analysis of randomized controlled trials코로나19 환자 사망률에 대한 토실리주맙의 효과: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-07-012022-09-12 Journal: International immunopharmacology [Category] SARS, 임상, 진단, [키워드] 28-day mortality 95% CI addition Admission AEs assigned benefit clinical Clinical efficacy Cochrane Library control group control groups COVID-19 COVID-19 patient Efficacy and safety eight enrolled Enrollment help ICU ICU admission Infection initial intensive care mechanical ventilation Meta-analysis Mortality no significant difference Patient patients with COVID-19 Placebo Primary outcome randomization Randomized controlled trial RCT RCTs receiving reduce registry risk Safe SARS-CoV-2 searched serious AE Standard of care subgroup analysis survival systematic review Tocilizumab Treatment treatment group treatment-emergent adverse event two group WHO [DOI] 10.1016/j.intimp.2021.107602 PMC 바로가기 [Article Type] Meta-Analysis
Evaluating the methodology of studies conducted during the global COVID-19 pandemic: A systematic review of randomized controlled trials전 세계 COVID-19 대유행 기간 동안 수행된 연구 방법론 평가: 무작위 대조 시험의 체계적인 검토Article Published on 2021-07-012022-09-11 Journal: Journal of integrative medicine [Category] SARS, 임상, [키워드] acute respiratory syndrome allocation concealment Blinding China Chongqing clinical care Clinical research Cochrane Handbook collected Comparisons conducted Consistency construction Controlled trial coronavirus disease Coronavirus disease 2019 Coronavirus pneumonia Coronavirus-2 COVID-19 COVID-19 RCT COVID-19 RCTs criteria data extraction deficiencies deficiency Descriptive statistics deviation disease eligible epidemic disease epidemic diseases Evaluating Evidence Excerpta Medica database exclusion exclusion criteria FIVE for inclusion global pandemic Guidance Handbook help implementation IMPROVE Inclusion information Infrastructure medRxiv Methodological quality methodology nCoV network Novel coronavirus novel coronavirus pneumonia outcome outcomes pandemic participant platform positive protocol provided Randomized controlled trial Randomized controlled trials RCT RCTs recruitment reported Repository Research researchers resulting review RTC Sample size Science Screening searched selective Seven Severe acute respiratory syndrome Severe acute respiratory syndrome-related coronavirus-2 Support systematic review systematic reviews therapeutic Therapeutic evidence. treating COVID-19 Treatment trials utility Variability Version VIP was done [DOI] 10.1016/j.joim.2021.03.003 PMC 바로가기 [Article Type] Article
Ivermectin and mortality in patients with COVID-19: A systematic review, meta-analysis, and meta-regression of randomized controlled trials코로나19 환자의 이버멕틴과 사망률: 무작위 대조 시험의 체계적인 검토, 메타 분석 및 메타 회귀Meta-Analysis Published on 2021-07-012022-09-11 Journal: Diabetes & metabolic syndrome [Category] SARS, 신약개발, 임상, [키워드] age Analysis benefit certainty of evidence ClinicalTrials control group coronavirus COVID-19 database databases decreased mortality diabete diabetes double-blinded hypertension inception intervention group Ivermectin Meta-analysis meta-regression Mortality Patient patients with COVID-19 Placebo placebo-controlled Primary outcome Randomized controlled trial RCT RCTs reduction reported required risk risk ratio SARS-CoV-2 sensitivity analysis severe COVID-19 Sex Standard of care statistical significance subgroup analysis systematic literature search systematic review therapy was performed was reduced [DOI] 10.1016/j.dsx.2021.102186 PMC 바로가기 [Article Type] Meta-Analysis
Effect of Tocilizumab in Reducing the Mortality Rate in COVID-19 Patients: A Systematic Review with Meta-AnalysisArticle Published on 2021-07-012022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] Analysis Anti-inflammatory drugs Characteristics COVID-19 COVID-19 mortality COVID-19 patients critical and severe patients critically ill patients Effect Effectiveness Efficacy evaluate group identify IMV Inconclusive Mechanic Meta-analysis Mortality mortality rate observational studies observational study Odds ratio outcome parameter patients treated performed Rate RCT RCTs recovery reducing reduction reveal review searched Seven ST alone Standard Standard therapy statistically significant subject survival TCZ therapy Tocilizumab treated [DOI] 10.3390/jpm11070628 PMC 바로가기 [Article Type] Article
Efficacy and safety of remdesivir in COVID-19 caused by SARS-CoV-2: a systematic review and meta-analysisSARS-CoV-2로 인한 COVID-19에서 렘데시비르의 효능 및 안전성: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-06-242022-09-11 Journal: BMJ Open [Category] SARS, 치료제, [키워드] 95% CI Analysis applied article benefit caused Clinical improvement clinical pharmacology Cochrane Central Cochrane review control group controlled trials COVID-19 decrease Effectiveness Efficacy eligibility eligible Evidence faster immunology Meta-analysis Methodological quality moderate Mortality no difference outcome participant patients Perspective Primary outcome randomised controlled trial RCT RCTs registration number Remdesivir Respiratory failure respiratory infections risk risk of bia RNA polymerase inhibitor screened secondary outcome Secondary outcomes Serious Adverse Event Serious Adverse Events shown Significant significant decrease Standard of care systematic review Treatment treatment of COVID-19 was done was performed was used with COVID-19 [DOI] 10.1136/bmjopen-2020-048416 PMC 바로가기 [Article Type] Meta-Analysis
A multi-center phase II randomized clinical trial of losartan on symptomatic outpatients with COVID-19Research article Published on 2021-06-172022-10-05 Journal: EClinicalMedicine [Category] 임상, [키워드] 1:1 95% CI ACE2 Adverse affected all-cause hospitalization analyzed angiotensin receptor blocker ARBs Arm Biotechnology blinded Cell clinically Community contributing to COVID-19 did not reduce disease disrupting Dyspnea Effects Efficacy enrolled enzyme event event rate expected finding functional funding Genomics glomerular filtration rate hospital Hospitalization hospitalizations likelihood losartan Lung injury Mild mitigate multicenter not differ outcome Outpatient outpatients participant Participants partnership Patient Placebo placebo-controlled Primary outcome proportion RAAS Randomized randomized clinical trial RCT Replication SARS-CoV-2 virus secondary significantly statistically Support supported symptom onset symptomatic symptomatic COVID-19 disease temperature treat Treatment treatment group Trial viral entry Viral load was reduced were blinded with COVID-19 [DOI] 10.1016/j.eclinm.2021.100957 [Article Type] Research article