Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle East respiratory syndrome coronavirusResearch Article Published on 2019-07-222022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] adenovirus-based Administered administration airway bind Bronchoalveolar lavage fluid candidate vaccine cause CD8 T cell Cellular immune response cellular receptor diarrhea Dipeptidyl peptidase 4 domain DPP4 exhibited expressing full-length glycoprotein highest humoral IgA antibody IgG antibody immune response immunization intramuscular intranasal intranasal route lung parenchyma measure memory MERS MERS-CoV MERS-CoV infection MERS-CoV S1 MERS-CoV vaccine Middle East N-terminal domain Neutralizing neutralizing antibody Neutralizing antibody titer neutralizing effect Protein Pseudotyped virus renal Respiratory illness respiratory syndrome coronavirus serum spike subunit Superior T cell response therapeutic Vaccine Vaccine development Vaccines vomiting [DOI] 10.1371/journal.pone.0220196 PMC 바로가기 [Article Type] Research Article
Burden and Risk Factors for Coronavirus Infections in Infants in Rural NepalArticles and Commentaries Published on 2018-11-152022-10-31 Journal: Clinical Infectious Diseases: An Official Publicat [Category] Coronavirus, [키워드] 229E 95% CI 95% confidence interval Acute respiratory infection acute respiratory symptom age ARI burden children collected Community conducted coronavirus Epidemiology Factor HKU1 Human illness immunization incidence incidence rate increase increased risk Infant Infants Infection Influenza Neonate Nepal NL63 OC43 peaking per 1000 person-years Poisson regression polymerase chain potential risk proportion Prospective randomized trial Respiratory illness respiratory virus Result risk factor South Asian study period Surveillance Swab symptomatic tested the disease Variation virus while [DOI] 10.1093/cid/ciy317 PMC 바로가기 [Article Type] Articles and Commentaries
Association between semi-quantitative microbial load and respiratory symptoms among Thai military recruits: a prospective cohort study태국 군인 신병의 반정량적 미생물 부하와 호흡기 증상 간의 연관성: 전향적 코호트 연구Research Article Published on 2018-09-142024-07-31 Journal: BMC Infectious Diseases [Category] 폐렴구균 감염증, [키워드] asymptomatic infection Haemophilus influenza Influenza influenza-like illness Multiplex PCR diagnostics Respiratory illness upper respiratory tract infection [DOI] 10.1186/s12879-018-3358-4 PMC 바로가기 [Article Type] Research Article
A Human DPP4-Knockin Mouse’s Susceptibility to Infection by Authentic and Pseudotyped MERS-CoVArticle Published on 2018-08-232022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] antiviral agent Antiviral agents authentic virus biosafety BSL-3 cause Dipeptidyl peptidase 4 expression hDPP4 high mortality rate Human Infection inhibitor locus m336 MERS-CoV mice Middle East mouse model neutralizing monoclonal antibodies Pathogenesis peptide pseudotyped Pseudotyped virus pulmonary disease Respiratory illness respiratory syndrome coronavirus resulting susceptible transgene virus [DOI] 10.3390/v10090448 PMC 바로가기 [Article Type] Article
Event based surveillance of Middle East Respiratory Syndrome Coronavirus (MERS- CoV) in Bangladesh among pilgrims and travelers from the Middle East: An update for the period 2013–2016Research Article Published on 2018-01-162022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] activities Algorithm Awareness Care conducted Control country disease emergence etiology family Fever H1N1 H3N2 Health Healthcare provider help hospital identify Infection influenza A influenza B MERS- CoV MERS-CoV MERS-CoV infection middle Middle East Ministry of Health occurred outbreak Patient PCR peak Prevent real time respiratory Respiratory illness respiratory pathogen respiratory symptom respiratory tract responsible Result returned Saudi Arabia Support Surveillance tested the disease the WHO Transmission viruses [DOI] 10.1371/journal.pone.0189914 PMC 바로가기 [Article Type] Research Article
Molecular characterization of human coronaviruses and their circulation dynamics in Kenya, 2009–2012Research Published on 2016-02-012022-10-28 Journal: Virology Journal [Category] Coronavirus, MERS, [키워드] Acute respiratory infection all age group amplification Analysis analyzed cells characterized children circulation diagnosed distribution eight Evidence FIVE HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 Hospitalization Human human coronavirus human coronaviruses identity Immunity individual Infection information inoculated isolate Kenya MERS-CoV molecular molecular characterization monolayer morbidity nasopharyngeal specimen polymerase positive Prevalence Primers real time Respiratory illness responsible Result RT-PCR sequence homology Sequencing shown specimen specimens strain Strains Variation virus [DOI] 10.1186/s12985-016-0474-x PMC 바로가기 [Article Type] Research
Sparse evidence of MERS-CoV infection among animal workers living in Southern Saudi Arabia during 2012Short Articles Published on 2015-03-032022-10-30 Journal: Influenza and Other Respiratory Viruses [Category] Coronavirus, MERS, [키워드] antibody cause collected conducted Control Evidence examined human serum Kingdom of Saudi Arabia lentiviral MERS-CoV MERS-CoV infection Middle East neutralization neutralized pseudoparticle virus neutralization assays Respiratory illness respiratory syndrome coronavirus Saudi Arabia sera serological evidence Spike protein viral pathogen zoonotic transmission [DOI] 10.1111/irv.12287 PMC 바로가기 [Article Type] Short Articles
Cluster of Middle East Respiratory Syndrome Coronavirus Infections in Iran, 2014Dispatch Published on 2015-02-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] Cluster coronavirus CoV Epidemiology Infection Iran Kerman Province MERS Middle East Middle East respiratory syndrome occurred Patient respiratory Respiratory illness respiratory infections respiratory syndrome coronavirus tested virus transmission viruses [DOI] 10.3201/eid2102.141405 PMC 바로가기 [Article Type] Dispatch
The impact of influenza A(H1N1)pdm09 compared with seasonal influenza on intensive care admissions in New South Wales, Australia, 2007 to 2010: a time series analysisResearch Article Published on 2012-10-122023-05-23 Journal: BMC Public Health [Category] Fulltext, 신종인플루엔자, [키워드] Australia Demand H1N1 hospitalisations Indigenous Influenza intensive care pandemic Pregnancy Respiratory illness [DOI] 10.1186/1471-2458-12-869 PMC 바로가기 [Article Type] Research Article
Co-circulation of Four Human Coronaviruses (HCoVs) in Queensland Children with Acute Respiratory Tract Illnesses in 2004Article Published on 2012-04-232022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] aetiology age ARI assay assigned children circulation clinical impact clinical severity score compared coronavirus detected develop diagnostic different HCoV-229E HCoV-HKU1 HCoV-NL63 HCoV-OC43 Human infectious Patient peaked positive random Real-time PCR reduce respiratory Respiratory illness respiratory specimen respiratory syncytial virus respiratory virus RT-rtPCR Screening serology Severity Score specimen tested tract transcriptase virus were used [DOI] 10.3390/v4040637 PMC 바로가기 [Article Type] Article