Efficacy of two siddha polyherbal decoctions, Nilavembu Kudineer and Kaba Sura Kudineer, along with standard allopathy treatment in the management of mild to moderate symptomatic COVID-19 patients—a double-blind, placebo-controlled, clinical trialRandomized Controlled Trial Published on 2021-08-282022-10-04 Journal: Trials [Category] MERS, SARS, 임상, [키워드] acute respiratory syndrome Adverse adverse effect adverse event age analyzed Arm ARMS assessment Asymptomatic baseline blood biochemical breathlessness C-reactive protein clinical symptom clinical trial Coronavirus-2 cough COVID-19 COVID-19 patient CRP D-dimer diagnosed diarrhea discharge discharged disease double-blind Double-blinded RCT drug ECG Effect effective Efficacy Electrolyte enrolled evaluate event female ferritin Fever hospital Hospital stay ICU IL6 Inflammatory marker intensive care interleukin-6 Kaba Sura Kudineer Kruskal-Wallis test lactate dehydrogenase LDH Liver function main outcome measure male management mean value Medicines Mild Mild to moderate COVID-19 moderate Moderate COVID-19 Nilavembu kudineer not significantly different parameter participant Patient Placebo placebo-controlled primary outcome measure Public health intervention pursuit Randomized recorded recruited reduction in renal function respective treatment Result RT-PCR Safe SARS-CoV-2 SARS-CoV-2 viral load severe symptom Siddha Siddha Medicine significantly statistically significant reduction Sura Symptom symptomatic the patient the placebo group therapy three group Treatment viral epidemics Viral load virus vomiting were recorded while [DOI] 10.1186/s13063-021-05478-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Qualitative Assessment of Early Adverse Effects of Pfizer–BioNTech and Sinopharm COVID-19 Vaccines by Telephone InterviewsArticle Published on 2021-08-262022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] administration Adverse adverse effect Adverse reaction Adverse reactions approach assessment Cohort COVID-19 COVID-19 pandemic COVID-19 vaccines dose Effect enrolled first dose Frequency injection site pain interview Mild no significant difference pandemic participant Pfizer Pfizer–BioNTech Pfizer–BioNTech Qualitative recipient reported second dose Side effect significantly higher Sinopharm telephone treatable vaccination Vaccine Vaccines [DOI] 10.3390/vaccines9090950 PMC 바로가기 [Article Type] Article
Adverse Cardiovascular Effects of Anti-COVID-19 DrugsPharmacology Published on 2021-08-252022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome addition Adverse adverse effect adverse effects Anti-COVID-19 Therapy Arrhythmias cardiovascular cardiovascular comorbidity cardiovascular complication cardiovascular complications cardiovascular diseases coronavirus COVID-19 COVID-19 infection COVID-19 patient death drug drugs Effect global pandemic heart failure higher risk Inflammation Intervention Myocardial infarction myocardial injury myocarditis Patient SARS-CoV-2 stroke therapeutic efficacy Venous Thromboembolism [DOI] 10.3389/fphar.2021.699949 PMC 바로가기 [Article Type] Pharmacology
A General Overview on the Hyperbaric Oxygen Therapy: Applications, Mechanisms and Translational OpportunitiesReview Published on 2021-08-242022-10-30 Journal: Medicina [Category] COVID-19, MERS, SARS, [키워드] adverse effect antimicrobial properties Bioavailability Blood Cancer Clinical management contraindication Coronavirus disease-19 (COVID-19) COVID-19 examined Hyperbaric oxygen therapy hyperbaric oxygen therapy (HBOT) hyperoxia hypoxic immunomodulatory Inclusion indication Inflammatory mechanisms opportunity oxygen Oxygen level Pathologies physiological plethora regions Research Support therapy tissue wound healing [DOI] 10.3390/medicina57090864 PMC 바로가기 [Article Type] Review
A Cross-Sectional Survey Exploring the Impact of the COVID-19 Pandemic on the Cancer Care of Adolescents and Young AdultsArticle Published on 2021-08-222022-10-31 Journal: Current Oncology [Category] COVID-19, MERS, SARS, [키워드] Adolescent adolescents and young adults adverse effect CAD Canada Cancer cancer treatment Care change changes in conducted COVID-19 COVID-19 pandemic Diagnosis diagnostic test Factor health condition healthcare identify Impact implementation majority Mental multiple logistic regression negative and positive oncology P -value pandemic Participants Perspective physical positive Support survey Virtual care was used [DOI] 10.3390/curroncol28040278 PMC 바로가기 [Article Type] Article
SARS-CoV-2 in diabetic pregnancies: a systematic scoping reviewResearch Published on 2021-08-212022-10-28 Journal: BMC Pregnancy and Childbirth [Category] COVID-19, MERS, [키워드] ACE2 adverse effect approach approaches assumed Care carried changes in CINAHL clinical diabete clinical implication Clinical management Clinical outcome Cochrane Library Collection complex interplay consequence core Course COVID-19 diabete diabetes Diabetes Mellitus Diabetic Digital effective Enzymes Epidemiology Epigenetic Evidence Features fetal gestation group hypoxemic hypoxia increased risk Interaction management mechanism Modification mother Neonatal outcomes pandemic pathophysiological mechanism platelet activation pregnancies Pregnancy pregnant women pro-inflammatory cytokines Prognosis recommendation Result SARS-CoV-2 starting point supplementary material systematic review the SARS-CoV-2 Transmission treat Web of Science women [DOI] 10.1186/s12884-021-03975-3 PMC 바로가기 [Article Type] Research
Adverse Effects on Work and Daily Life Interference among Healthcare Workers after the First and Second ChAdOx1 and BNT162b2 COVID-19 Vaccine DosesArticle Published on 2021-08-192022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Adverse adverse effect age Analysis BNT162b2 BNT162b2 vaccine ChAdOx1 COVID-19 COVID-19 vaccines Daily dose doses Effect Factor first dose General population incidence interaction term Interference life multivariate model no difference participant Participants receiving second second dose Side effect significantly lower the vaccine Vaccinations Vaccine vaccine dose work worker [DOI] 10.3390/vaccines9080926 PMC 바로가기 [Article Type] Article
Codominant IgG and IgA expression with minimal vaccine mRNA in milk of BNT162b2 vaccineesArticle Published on 2021-08-192022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] adverse effect Antenatal BNT162b2 vaccine Breastfeeding COVID-19 COVID-19 vaccination disease dose Efficacy Evidence expression had no human milk IgA IgA level IgG IgG antibody IgG titer Infant Influenza initial lactating mother mRNA mRNA vaccination of BNT162b2 Outcomes research produced profile Protective antibody protective immunity recommendation reported SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody secreted significant increase subsequent Support the vaccine transfer vaccination Vaccine vaccinee viral infection women [DOI] 10.1038/s41541-021-00370-z PMC 바로가기 [Article Type] Article
Understanding and countering the spread of conspiracy theories in social networks: Evidence from epidemiological models of Twitter dataResearch Article Published on 2021-08-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] absence adverse effect approach Compliance COVID-19 pandemic Critical dataset diffusion Diseases early response early stage Effect effective Efficacy Enrollment Epidemic epidemiological Evidence Extended Generalizability less mechanism moderate pandemic public health measure Result searched Spread understanding Validity were used [DOI] 10.1371/journal.pone.0256179 PMC 바로가기 [Article Type] Research Article
Melatonin as a Potential Adjuvant Treatment for COVID-19 beyond Sleep DisordersReview Published on 2021-08-112022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] Activation adjuvant adverse effect anti-SARS-CoV-2 cells change COVID-19 COVID-19 patients COVID-19 progression COVID-19 vaccination Deterioration Disease progression disorder Effect Effects Efficacy Free radicals hyper-inflammation immune cells inhibit Insomnia lack limit Lungs melatonin multiorgan failure Patient patients with COVID-19 physiological effects Potential preclinical data randomized clinical trial reduce Registered resulting risk safety profile Sleep Sleep disturbance sleep quality the SARS-CoV-2 virus therapeutic option tissue treat Treatment Ventilator-induced lung injury [DOI] 10.3390/ijms22168623 PMC 바로가기 [Article Type] Review