Chronic obstructive pulmonary disease and the COVID-19 pandemic: Reciprocal challengesEditorial Published on 2020-11-012023-07-12 Journal: Respiratory medicine and research [Category] SARS, [키워드] COPD COVID-19 Infection [DOI] 10.1016/j.resmer.2020.100764 PMC 바로가기 [Article Type] Editorial
Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors건강 및 천식, COPD, 비만, 고혈압 및 COVID-19 위험 요소의 조직 및 면역 세포에서 ACE2, CD147, CD26 및 기타 SARS-CoV-2 관련 분자의 분포Article Published on 2020-11-012022-08-31 Journal: Allergy [Category] SARS, 바이오마커, 유전자 메커니즘, 치료제, [키워드] ACE2 Adults age Altered analyzed Asthma atopic dermatitis B cells BAL Blood BMI bronchial epithelial cells Bronchoalveolar lavage fluid BSG caused CD147 CD26 CD4 CD8 clinical presentation co-expression coexpressed Comorbidity contribute COPD correlated COVID-19 COVID-19 children database DCs disease disease status DPP4 epithelial epithelial cells expression expression profile Factor Gender Gene Expression Health healthy children healthy subject healthy subjects human cell human cells hypertension Immune cell immune cells Infection involved lung male material molecular Monocytes mononuclear cell mononuclear cells morbidity Mortality Neutrophils NK cells Novel coronavirus novel coronavirus SARS-CoV-2 obesity Patient PBMC PBMCs performed Peripheral blood Peripheral blood mononuclear cells plasmablasts PPIA PPIB primary human bronchial epithelial cells primary human cell primary human cells receptor reported risk factor Risk factors RNA sequencing SARS receptor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor SARS-CoV-2 receptors severity skin skin biopsies smoking T cell T cells the disease the SARS-CoV-2 tissue tissues TMPRSS2 were expressed Whole blood [DOI] 10.1111/all.14429 PMC 바로가기 [Article Type] Article
The paradoxical effect of IL-6 and implications for the use of Tocilizumab in Covid-19 patientsIL-6의 역설적 효과와 코비드-19 환자에서 토실리주맙 사용에 대한 의미Editorial Published on 2020-11-012022-09-12 Journal: Medical Hypotheses [Category] B형 간염, 진단, [키워드] affected AIDS anti-inflammatory cytokine ARDS chronic obstructive Comorbidity Concentration condition COPD Cytokine storm deaths Deterioration Elevation example explain HIV HIV patients Hypothesis IL-6 implication intensive care units life-threatening Mild Mortality paradoxical pathogen Patient pro-inflammatory progression promote Protective protective effect pulmonary disease respiratory responsible SARS-CoV-2 pandemic shown Treatment Viral diseases viral infections [DOI] 10.1016/j.mehy.2020.110284 PMC 바로가기 [Article Type] Editorial
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platformArticles Published on 2020-11-012022-10-29 Journal: The Lancet. Respiratory Medicine [Category] COVID-19, Fulltext, SARS, [키워드] 95% CI acute respiratory disease acute respiratory syndrome adjusted age analysed Analysis association Asthma calculated category chronic obstructive Cohort combination therapy COPD coronavirus covariates COVID-19 COVID-19 pandemic COVID-19-related death Cox regression model database death description diagnosed disease severity E-value EHR Electronic health record eligible England expected explained finding Follow-up funding hazard ratio Health high-dose ICS hospital HRs ICS ICSs increased risk individual Infection Inhaled inhaled corticosteroid LABA–LAMA LABA–LAMA combination long-acting muscarinic antagonist low-dose Medical Research Council medium dose Observational cohort study Observed office Older OpenSAFELY outcome Patient people with asthma people with COPD platform Prevalence primary care PROTECT pulmonary disease recorded respiratory medication SABA Sex short-acting β agonist smoker Statistics Support were given [DOI] 10.1016/S2213-2600(20)30415-X PMC 바로가기 [Article Type] Articles
Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamideCell Death & Injury Published on 2020-10-302022-10-28 Journal: Bioscience Reports [Category] COVID-19, MERS, SARS, [키워드] activated Activation ADP-ribose Aryl hydrocarbon receptor ATP biochemical Cancer caused cell death chronic obstructive clinical care component COPD Coronaviruses COVID-19 Critical cytokine determine drugs effective Efficacy ENhance enzyme event expression Gene Expression glucocorticoid Glucocorticoids HIV infection homologue Immunity Immunotherapy Indoleamine 2,3-dioxygenase induce information inhibit inhibitor intensive care Kynurenine pathway lung Lung injury NADP nicotinamide nuclear overexpressed PARP pathophysiology Patient patient mortality Poly (ADP-ribose) polymerase polymerase potent Prevent proinflammatory Proinflammatory cytokine pulmonary disease regulate Regulation respiratory syncytial virus RSV sequence silent sirtuin therapeutic use therapy Trial [DOI] 10.1042/BSR20202856 PMC 바로가기 [Article Type] Cell Death & Injury
Risk factors associated with morbidity and mortality outcomes of COVID-19 patients on the 28th day of the disease course: a retrospective cohort study in BangladeshOriginal Paper Published on 2020-10-292022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, SARS, [키워드] 95% CI age AOR CHD Chronic kidney disease chronic liver disease chronic obstructive CKD CLD Cohort collected Comorbidity conducted COPD Coronary heart disease coronavirus disease Course COVID-19 COVID-19 patient COVID-19 patients Diabetes Mellitus diagnosed Factor hypertension identify Intervention Major majority male malignant disease morbidity morbidity and mortality mortality and outcomes mortality rate mortality risk non-survivor outcome outcomes Patient proportion pulmonary disease questionnaire retrospective cohort study risk risk factor Risk factors smokeless the disease the patient urban [DOI] 10.1017/S0950268820002630 PMC 바로가기 [Article Type] Original Paper
Diagnosis of COVID-19 by analysis of breath with gas chromatography-ion mobility spectrometry – a feasibility studyResearch article Published on 2020-10-242022-10-05 Journal: EClinicalMedicine [Category] 바이오마커, [키워드] 95% CI Accuracy acetone Aldehydes Analysis approach Asthma AUROC Bacterial breath Breath-analysis Breath-testing career Cohort Compound condition conditions Contact COPD COVID-19 COVID-19 diagnostics COVID-19 infection development diagnose Diagnosis diagnosis of COVID-19 differentiation Dortmund Edinburgh Effects Endemic ethanal feasibility finding flu funding Gas chromatography-ion mobility spectrometry GC-IMS Germany health-care healthcare hospital identity Inflammatory Influenza ketones Laboratory marker methanol Multi-variate analysis Multivariate analysis NHS Non-COVID-19 Other participant Patient patients with COVID-19 Pneumonia polymerase chain predictive power prevalence study PROTECT qPCR recruited sensitivity specificity Support supported Swab tested Transcription university VoC with COVID-19 [DOI] 10.1016/j.eclinm.2020.100609 [Article Type] Research article
Prevalence of underlying diseases in died cases of COVID-19: A systematic review and meta-analysisResearch Article Published on 2020-10-232022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Analysis article Asthma cardiovascular disease Cerebrovascular disease conducted COPD COVID-19 COVID-19 cases Critical database diabete diabetes died disease greater Health high mortality rate highest hypertension Liver disease lowest Lung disease malignancy Meta-analysis morbidity and mortality most prevalent comorbidity outcomes people with COVID-19 Population Prevalence protocols reported Result searched Severity of disease systematic review underlying disease was related Web of Science [DOI] 10.1371/journal.pone.0241265 PMC 바로가기 [Article Type] Research Article
Inhaled Corticosteroids and COVID-19 Risk and Mortality: A Nationwide Cohort StudyArticle Published on 2020-10-232022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI adjusted age Analysis assessment association Asthma Case-control case-control study chronic obstructive pulmonary disease Clinical outcome Comorbidities Control COPD coronavirus disease COVID-19 database death evaluate evaluated hospital Hospitalized ICS inhaled corticosteroid insurance Korean not significant outcomes Patient patients with COVID-19 review risk SARS-CoV-2 Sex significantly Steroids susceptibility was performed with COVID-19 [DOI] 10.3390/jcm9113406 PMC 바로가기 [Article Type] Article
The Experience of COPD Patients in Lockdown Due to the COVID-19 PandemicObservational Study Published on 2020-10-232023-07-05 Journal: International journal of chronic obstructive pulmo [Category] SARS, [키워드] COPD COVID-19 lockdown [DOI] 10.2147/COPD.S268421 PMC 바로가기 [Article Type] Observational Study